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Peer-reviewedCC BY 4.0International Journal of Molecular Sciences

Natural Bioactive Compounds in Cosmeceuticals: Challenges and Future Perspectives

  1. 1Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario Monte S. Angelo, Via Cintia, 80126 Naples, Italy

Abstract

The global cosmetic market is experiencing dramatic growth, and it is shifting significantly toward the use of natural substances rather than synthetic ingredients in cosmetic formulations. Natural bioactive compounds, obtained from plants, are used in the modern cosmetic industry in order to enhance skin appearance and provide biological bene-fits. These compounds include flavonoids, terpenoids, steroids, fatty acids, and vitamins with anti-aging, antioxidant, anti-inflammatory, and antimicrobial properties. Most previous studies have focused on plant extracts and their general effects on human skin, without bridging the gap between systematic classification of bioactive compounds and their cosmetic applications. Therefore, the aim of this article is to provide a novel framework for bioactive compounds which are utilized in cosmeceuticals. Additionally, it discusses biological activities of each compound associated with skin well-being, its applications in the cosmetic industry, as well as its general challenges and limitations in cosmetic formulations.

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BibTeX
@article{tehrani2026natural,
  title = {{Natural Bioactive Compounds in Cosmeceuticals: Challenges and Future Perspectives}},
  author = {Firoozeh Kavosh Tehrani and Marco Masi},
  journal = {International Journal of Molecular Sciences},
  year = {2026},
  month = oct,
  doi = {10.3390/ijms27219709},
  url = {https://www.mdpi.com/1422-0067/27/21/9709},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Natural Bioactive Compounds in Cosmeceuticals: Challenges and Future Perspectives
AU  - Firoozeh Kavosh Tehrani
AU  - Marco Masi
PY  - 2026
DA  - 2026/10/29
JO  - International Journal of Molecular Sciences
DO  - 10.3390/ijms27219709
UR  - https://www.mdpi.com/1422-0067/27/21/9709
AB  - The global cosmetic market is experiencing dramatic growth, and it is shifting significantly toward the use of natural substances rather than synthetic ingredients in cosmetic formulations. Natural bioactive compounds, obtained from plants, are used in the modern cosmetic industry in order to enhance skin appearance and provide biological bene-fits. These compounds include flavonoids, terpenoids, steroids, fatty acids, and vitamins with anti-aging, antioxidant, anti-inflammatory, and antimicrobial properties. Most previous studies have focused on plant extracts and their general effects on human skin, without bridging the gap between systematic classification of bioactive compounds and their cosmetic applications. Therefore, the aim of this article is to provide a novel framework for bioactive compounds which are utilized in cosmeceuticals. Additionally, it discusses biological activities of each compound associated with skin well-being, its applications in the cosmetic industry, as well as its general challenges and limitations in cosmetic formulations.
SN  - 1422-0067
ER  -