Variable resistance to spot form net blotch disease at a barley chromosome 7 H locus
- 1Centre for Crop and Disease Management, School of Molecular and Life Sciences, Curtin University
Abstract
Five genetically diverse barley lines were crossed to a modern susceptible cultivar to investigate resistance genes and their allelic variation in response to spot form net blotch. Doubled haploid populations were phenotyped at three growth stages, revealing quantitative trait loci (QTLs) on six of the seven barley chromosomes. A major dominant susceptibility locus on the long arm of chromosome 7 H was present in all populations, with the phenotypic variance explained (PVE) at the heading stage, for example, ranging from 22 to 48%, while being absent in one population except at heading. Genetic mapping separated the locus into three distinct genetic windows, suggesting the presence of different resistance genes, or conversely structural rearrangements or other factors affecting QTL positions. Eleven minor QTLs were evident at different developmental stages, with PVE values ranging from 6 to 14%. Several of these increased in effect size towards heading, coincident with reduced significance of the major 7 H locus, suggestive of epistasis or phased gene expression. The interplay between the minor loci and the 7 H locus further demonstrates the genetic complexity of Pyrenophora teres f. maculata–barley interactions and provides novel genes which may be combined for effective resistance.
Related
- Multi-isolate GWAS identifies broad-spectrum and isolate-specific resistance-associated loci for Septoria tritici blotch in synthetic hexaploid wheat.
- Base editing of EIF4E creates novel resistance alleles against bymoviruses in winter barley
- Microbial succession in casing layer shapes bacterial blotch disease associated communities in cultivated white button mushroom: From casing layer to disease
- Engineering an Exo70 integrated domain of a barley NLR for improved blast resistance
- Genome-wide characterisation of leaf rust resistance loci in an Eastern European barley collection.
BibTeX
@article{dinh2026variable,
title = {{Variable resistance to spot form net blotch disease at a barley chromosome 7 H locus}},
author = {Hoan Dinh and Mariano J. Muria-Gonzalez and Julie A. Lawrence and Nola K. D’Souza and Shota Morikawa and Elzette Palmiero and Simon R. Ellwood},
journal = {Scientific Reports},
year = {2026},
month = sep,
doi = {10.1038/s41598-026-70764-3},
url = {https://doi.org/10.1038/s41598-026-70764-3},
note = {CC BY},
}
RIS
TY - JOUR
TI - Variable resistance to spot form net blotch disease at a barley chromosome 7 H locus
AU - Hoan Dinh
AU - Mariano J. Muria-Gonzalez
AU - Julie A. Lawrence
AU - Nola K. D’Souza
AU - Shota Morikawa
AU - Elzette Palmiero
AU - Simon R. Ellwood
PY - 2026
DA - 2026/09/01
JO - Scientific Reports
DO - 10.1038/s41598-026-70764-3
UR - https://doi.org/10.1038/s41598-026-70764-3
AB - Five genetically diverse barley lines were crossed to a modern susceptible cultivar to investigate resistance genes and their allelic variation in response to spot form net blotch. Doubled haploid populations were phenotyped at three growth stages, revealing quantitative trait loci (QTLs) on six of the seven barley chromosomes. A major dominant susceptibility locus on the long arm of chromosome 7 H was present in all populations, with the phenotypic variance explained (PVE) at the heading stage, for example, ranging from 22 to 48%, while being absent in one population except at heading. Genetic mapping separated the locus into three distinct genetic windows, suggesting the presence of different resistance genes, or conversely structural rearrangements or other factors affecting QTL positions. Eleven minor QTLs were evident at different developmental stages, with PVE values ranging from 6 to 14%. Several of these increased in effect size towards heading, coincident with reduced significance of the major 7 H locus, suggestive of epistasis or phased gene expression. The interplay between the minor loci and the 7 H locus further demonstrates the genetic complexity of Pyrenophora teres f. maculata–barley interactions and provides novel genes which may be combined for effective resistance.
SN - 2045-2322
ER -