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Peer-reviewedCC BYGels (Basel, Switzerland)

Blackcurrant (R. nigrum) Pomace Extract-Loaded Hydrogels: A Sustainable Alginate-Inulin Matrix for Polyphenol Delivery.

  • Diāna Brūvere1
  • Ance Bārzdiņa1,2
  • Renārs Broks3
  • Rudīte Koka3
  • Renāte Teterovska1,2
  1. 1Department of Applied Pharmacy, Faculty of Pharmacy, Rīga Stradiņš University, LV-1007 Riga, Latvia.
  2. 2Baltic Biomaterials Centre of Excellence, Riga Technical University, P. Valdena Str. 3, LV-1048 Riga, Latvia.
  3. 3Department of Biology and Microbiology, Rīga Stradiņš University, LV-1007 Riga, Latvia.
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Abstract

Blackcurrant (Ribes nigrum) is rich in polyphenols and is known for its antioxidant and anti-inflammatory properties, yet its processing byproducts (pomace) remain underutilized. This study aimed to develop and characterize R. nigrum pomace extract-loaded alginate-inulin hydrogel for potential topical application, thus promoting the valorization of R. nigrum pomace extract. Comparative extract analysis demonstrated that the pomace extract contained the highest levels of total polyphenols (71.0 mg GAE/g dried extract) and tannins (21.8%) and exhibited the most promising antibacterial activity (MIC 3.1-6.3 mg/mL), although its antiradical activity was relatively lower than that of juice and berry extracts. Furthermore, the obtained hydrogels were structurally stable and provided a gradual release of polyphenols at pH 5.5, with 80% released within 24 h. Incorporation of R. nigrum pomace extract increased the swelling of the hydrogels and improved viscoelastic recovery. Overall, the findings highlight the potential of R. nigrum pomace as a sustainable bioactive component in alginate-inulin hydrogel systems for potential topical applications in wound care.

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Cite

BibTeXRIS
BibTeX
@article{bruvere2026blackcurrant,
  title = {{Blackcurrant (R. nigrum) Pomace Extract-Loaded Hydrogels: A Sustainable Alginate-Inulin Matrix for Polyphenol Delivery.}},
  author = {Diāna Brūvere and Ance Bārzdiņa and Renārs Broks and Rudīte Koka and Renāte Teterovska},
  journal = {Gels (Basel, Switzerland)},
  year = {2026},
  month = oct,
  doi = {10.3390/gels12100929},
  url = {https://europepmc.org/article/MED/42929963},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Blackcurrant (R. nigrum) Pomace Extract-Loaded Hydrogels: A Sustainable Alginate-Inulin Matrix for Polyphenol Delivery.
AU  - Diāna Brūvere
AU  - Ance Bārzdiņa
AU  - Renārs Broks
AU  - Rudīte Koka
AU  - Renāte Teterovska
PY  - 2026
DA  - 2026/10/15
JO  - Gels (Basel, Switzerland)
DO  - 10.3390/gels12100929
UR  - https://europepmc.org/article/MED/42929963
AB  - Blackcurrant (Ribes nigrum) is rich in polyphenols and is known for its antioxidant and anti-inflammatory properties, yet its processing byproducts (pomace) remain underutilized. This study aimed to develop and characterize R. nigrum pomace extract-loaded alginate-inulin hydrogel for potential topical application, thus promoting the valorization of R. nigrum pomace extract. Comparative extract analysis demonstrated that the pomace extract contained the highest levels of total polyphenols (71.0 mg GAE/g dried extract) and tannins (21.8%) and exhibited the most promising antibacterial activity (MIC 3.1-6.3 mg/mL), although its antiradical activity was relatively lower than that of juice and berry extracts. Furthermore, the obtained hydrogels were structurally stable and provided a gradual release of polyphenols at pH 5.5, with 80% released within 24 h. Incorporation of R. nigrum pomace extract increased the swelling of the hydrogels and improved viscoelastic recovery. Overall, the findings highlight the potential of R. nigrum pomace as a sustainable bioactive component in alginate-inulin hydrogel systems for potential topical applications in wound care.
SN  - 2310-2861
ER  -