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Peer-reviewedLicence not statedNature

Tandem repeat variation shapes immune cell type-specific gene expression

  • Hope A. Tanudisastro1,2,3,4,5
  • Anna S. E. Cuomo6,7,8,9,10,5
  • Ben Weisburd11,12,13
  • Matthew J. Welland6,7,5
  • Eleanor Spenceley8,9,10,5
  • Michael Franklin6,7,5
  • Angli Xue8,9,10,5
  • Hao Lawrence Huang8,9,10,5
  • Blake Bowen8,9,10,14
  • Jianan Fan8,9,10,15
  • Oscar A. Dong16,15
  • Albert Henry8,9,10,5
46 more authors
  • Peter C. Allen8,9,10,17
  • Kristof Wing18,19,20,21
  • Owen Tang22,23,24,25
  • Michael Gray22,23,24,21
  • Andre L. M. Reis8,26,21
  • Jonathan Margoliash27,5
  • Nehir E. Kurtas28,29,5
  • Jeffrey M. Pullin30,5
  • Arthur S. Lee28,29,5
  • Harrison Brand28,29,5
  • Michael Harper6,7,5
  • Katalina Bobowik6,7,5
  • Michael A. Silk6,7,5
  • Amy Miniter6,7,5
  • John F. Marshall6,7,31
  • Vivian Bakiris6,7,32
  • Bindu Swapna Madala6,7,33
  • Caitlin Uren6,7,5
  • Caitlin Bartie8,9,10,34
  • Rachael A. McCloy8,9,10,15
  • Anne Senabouth8,9,10,13
  • Harriet Dashnow35,34
  • Liam G. Fearnley36,37,38,5
  • Alejandro Martin-Trujillo39,5
  • Egor Dolzhenko40,5
  • Zhen Qiao8,26,5
  • Stuart M. Grieve5
  • Tung Nguyen22,23,24,25
  • Eyal Ben‐David17
  • Ling Chen5
  • Kyle Kai‐How Farh14
  • Michael E. Talkowski28,29,34
  • Stephen I. Alexander23,5
  • Owen M. Siggs8,26,5
  • Leonhard Gruenschloss6,7,5
  • Hannah Nicholas6,7
  • Jennifer Piscionere6,7
  • Cas Simons6,7
  • Chris Wallace30
  • Melissa Gymrek27
  • Ira W. Deveson8,26
  • Alex William Hewitt18,19,20
  • Gemma Alexandra Figtree22,23,24
  • Katrina M. de Lange6,7
  • Joseph E. Powell8,9,10
  • Daniel G. MacArthur
40 affiliations
  1. 1Centre for Population Genomics, Garvan Institute of Medical Research, and UNSW Sydney, Sydney, New South Wales, Australia. [email protected]
  2. 2Centre for Population Genomics, Murdoch Children's Research Institute, Melbourne, Victoria, Australia. [email protected]
  3. 3Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia. [email protected]
  4. 4Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia. [email protected]
  5. 5Garvan Institute of Medical Research
  6. 6Centre for Population Genomics, Garvan Institute of Medical Research, and UNSW Sydney, Sydney, New South Wales, Australia
  7. 7Centre for Population Genomics, Murdoch Children's Research Institute, Melbourne, Victoria, Australia
  8. 8Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia
  9. 9Garvan-Weizmann Centre for Cellular Genomics, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
  10. 10UNSW Cellular Genomics Futures Institute, University of New South Wales, Sydney, New South Wales, Australia
  11. 11Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA
  12. 12Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA
  13. 13Broad Institute
  14. 14Menzies Institute for Medical Research
  15. 15Kolling Institute of Medical Research
  16. 16Faculty of Science, University of Sydney, Sydney, New South Wales, Australia
  17. 17University of California, San Diego
  18. 18Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, Australia
  19. 19Department of Ophthalmology, Royal Hobart Hospital, Hobart, Tasmania, Australia
  20. 20Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia
  21. 21Broad Institute of MIT and Harvard
  22. 22Charles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia
  23. 23Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia
  24. 24Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, New South Wales, Australia
  25. 25University of Cambridge
  26. 26Genomics and Inherited Disease Program, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
  27. 27Department of Medicine, University of California, San Diego, CA, USA
  28. 28Massachusetts General Hospital, Boston, MA, USA
  29. 29The Broad Institute of MIT and Harvard, Cambridge, MA, USA
  30. 30MRC Biostatistics Unit, University of Cambridge, Cambridge, UK
  31. 31University of Colorado
  32. 32The Walter and Eliza Hall Institute of Medical Research
  33. 33Pacific Biosciences of California
  34. 34University of Sydney
  35. 35Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA
  36. 36Bruce Lefroy Centre, Murdoch Children's Research Institute, Parkville, Victoria, Australia
  37. 37Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia
  38. 38Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
  39. 39Department of Genetics and Genomics Sciences and Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA
  40. 40Pacific Biosciences of California, Menlo Park, CA, USA
Open at sourceDOICite

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Cite

BibTeXRIS
BibTeX
@article{tanudisastro2026tandem,
  title = {{Tandem repeat variation shapes immune cell type-specific gene expression}},
  author = {Hope A. Tanudisastro and Anna S. E. Cuomo and Ben Weisburd and Matthew J. Welland and Eleanor Spenceley and Michael Franklin and Angli Xue and Hao Lawrence Huang and Blake Bowen and Jianan Fan and Oscar A. Dong and Albert Henry and Peter C. Allen and Kristof Wing and Owen Tang and Michael Gray and Andre L. M. Reis and Jonathan Margoliash and Nehir E. Kurtas and Jeffrey M. Pullin and Arthur S. Lee and Harrison Brand and Michael Harper and Katalina Bobowik and Michael A. Silk and Amy Miniter and John F. Marshall and Vivian Bakiris and Bindu Swapna Madala and Caitlin Uren and Caitlin Bartie and Rachael A. McCloy and Anne Senabouth and Harriet Dashnow and Liam G. Fearnley and Alejandro Martin-Trujillo and Egor Dolzhenko and Zhen Qiao and Stuart M. Grieve and Tung Nguyen and Eyal Ben‐David and Ling Chen and Kyle Kai‐How Farh and Michael E. Talkowski and Stephen I. Alexander and Owen M. Siggs and Leonhard Gruenschloss and Hannah Nicholas and Jennifer Piscionere and Cas Simons and Chris Wallace and Melissa Gymrek and Ira W. Deveson and Alex William Hewitt and Gemma Alexandra Figtree and Katrina M. de Lange and Joseph E. Powell and Daniel G. MacArthur},
  journal = {Nature},
  year = {2026},
  month = oct,
  doi = {10.1038/s41586-026-10438-2},
  url = {https://doi.org/10.1101/2024.11.02.621562},
}
RIS
TY  - JOUR
TI  - Tandem repeat variation shapes immune cell type-specific gene expression
AU  - Hope A. Tanudisastro
AU  - Anna S. E. Cuomo
AU  - Ben Weisburd
AU  - Matthew J. Welland
AU  - Eleanor Spenceley
AU  - Michael Franklin
AU  - Angli Xue
AU  - Hao Lawrence Huang
AU  - Blake Bowen
AU  - Jianan Fan
AU  - Oscar A. Dong
AU  - Albert Henry
AU  - Peter C. Allen
AU  - Kristof Wing
AU  - Owen Tang
AU  - Michael Gray
AU  - Andre L. M. Reis
AU  - Jonathan Margoliash
AU  - Nehir E. Kurtas
AU  - Jeffrey M. Pullin
AU  - Arthur S. Lee
AU  - Harrison Brand
AU  - Michael Harper
AU  - Katalina Bobowik
AU  - Michael A. Silk
AU  - Amy Miniter
AU  - John F. Marshall
AU  - Vivian Bakiris
AU  - Bindu Swapna Madala
AU  - Caitlin Uren
AU  - Caitlin Bartie
AU  - Rachael A. McCloy
AU  - Anne Senabouth
AU  - Harriet Dashnow
AU  - Liam G. Fearnley
AU  - Alejandro Martin-Trujillo
AU  - Egor Dolzhenko
AU  - Zhen Qiao
AU  - Stuart M. Grieve
AU  - Tung Nguyen
AU  - Eyal Ben‐David
AU  - Ling Chen
AU  - Kyle Kai‐How Farh
AU  - Michael E. Talkowski
AU  - Stephen I. Alexander
AU  - Owen M. Siggs
AU  - Leonhard Gruenschloss
AU  - Hannah Nicholas
AU  - Jennifer Piscionere
AU  - Cas Simons
AU  - Chris Wallace
AU  - Melissa Gymrek
AU  - Ira W. Deveson
AU  - Alex William Hewitt
AU  - Gemma Alexandra Figtree
AU  - Katrina M. de Lange
AU  - Joseph E. Powell
AU  - Daniel G. MacArthur
PY  - 2026
DA  - 2026/10/28
JO  - Nature
DO  - 10.1038/s41586-026-10438-2
UR  - https://doi.org/10.1101/2024.11.02.621562
SN  - 0028-0836
SN  - 1476-4687
ER  -