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Peer-reviewedCC BYJournal of surgical case reports

Acute crystalline lens opacification following intracameral phenylephrine during retinal detachment surgery requiring unplanned phaco-vitrectomy.

  • Ananth Ranjit1
  • Panagiotis Tsoutsanis1,2
  • Konstantinos Kaprinis1
  1. 1Department of Ophthalmology, Northern Care Alliance NHS Foundation Trust, Rochdale Infirmary, Whitehall St, Rochdale OL12 0NB, United Kingdom.
  2. 2School of Medical Sciences, Faculty of Biology, Medicine and Healthy, The University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PL, United Kingdom.
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Abstract

Intracameral phenylephrine is commonly used during intraocular surgery to facilitate pupillary dilation. Previous reports have described transient anterior capsule and cortical lens discolouration following intracameral phenylephrine administration. We describe a case of acute crystalline lens opacification developing immediately following intracameral phenylephrine administration during pars plana vitrectomy for rhegmatogenous retinal detachment. The resultant loss of retinal visualization necessitated conversion to an unplanned phaco-vitrectomy. Vitreoretinal surgeons should be aware of this rare but potentially significant complication when using intracameral phenylephrine in phakic eyes.

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Cite

BibTeXRIS
BibTeX
@article{ranjit2026acute,
  title = {{Acute crystalline lens opacification following intracameral phenylephrine during retinal detachment surgery requiring unplanned phaco-vitrectomy.}},
  author = {Ananth Ranjit and Panagiotis Tsoutsanis and Konstantinos Kaprinis},
  journal = {Journal of surgical case reports},
  year = {2026},
  month = oct,
  doi = {10.1093/jscr/rjag978},
  url = {https://europepmc.org/article/MED/42948478},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Acute crystalline lens opacification following intracameral phenylephrine during retinal detachment surgery requiring unplanned phaco-vitrectomy.
AU  - Ananth Ranjit
AU  - Panagiotis Tsoutsanis
AU  - Konstantinos Kaprinis
PY  - 2026
DA  - 2026/10/27
JO  - Journal of surgical case reports
DO  - 10.1093/jscr/rjag978
UR  - https://europepmc.org/article/MED/42948478
AB  - Intracameral phenylephrine is commonly used during intraocular surgery to facilitate pupillary dilation. Previous reports have described transient anterior capsule and cortical lens discolouration following intracameral phenylephrine administration. We describe a case of acute crystalline lens opacification developing immediately following intracameral phenylephrine administration during pars plana vitrectomy for rhegmatogenous retinal detachment. The resultant loss of retinal visualization necessitated conversion to an unplanned phaco-vitrectomy. Vitreoretinal surgeons should be aware of this rare but potentially significant complication when using intracameral phenylephrine in phakic eyes.
SN  - 2042-8812
ER  -