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Peer-reviewedCC BY 4.0PLOS One

Herbal or conventional medicine? A cross-sectional study of Jordanian university students’ preferences for cold and flu treatment

  1. 1Department of Pediatrics, Family Medicine, and Gynecology, Faculty of Medicine, Yarmouk University, Irbid, Jordan
  2. 2Department of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan

Abstract

Background: University students frequently self-manage common cold and influenza symptoms using herbal remedies, pharmaceutical treatments, or both. However, evidence regarding treatment preferences among Jordanian university students remains limited. Objective: To assess treatment preferences and factors associated with four outcomes: first-line treatment choice, timing of treatment initiation, response to perceived herbal treatment failure, and medication-obtaining behavior. Methods: An observational cross-sectional study was conducted in Jordan among 1,797 undergraduate students from 16 April to 16 September 2025 using a confidential, de-identified Arabic online questionnaire. Descriptive statistics and multinomial logistic regression were used to evaluate the four outcomes. Adjusted odds ratios (aORs) with 95% confidence intervals (CIs) were reported. Results: Combined therapy was the most common first-line choice (44.5%), and 42.5% initiated treatment on the same day. Female participants had higher odds of preferring combined therapy than males (aOR = 2.55, 95% CI: 1.64–3.96; p < 0.001), whereas medical-field students had lower odds of same-day treatment initiation (aOR = 0.55, 95% CI: 0.42–0.72; p < 0.001). After perceived herbal treatment failure, 50.7% switched to pharmaceutical treatments; reliance on doctor-prescribed treatments was associated with lower odds of continuing herbal remedies (aOR = 0.38, 95% CI: 0.27–0.51; p < 0.001) or combining herbal and pharmaceutical treatments (aOR = 0.56, 95% CI: 0.45–0.70; p < 0.001). Regarding medication-obtaining behavior, 28.2% purchased pharmaceutical treatments without a prescription based on personal experience, and medical-field students had higher odds of this behavior (aOR = 1.76, 95% CI: 1.39–2.23; p < 0.001). Conclusions: Treatment decisions reflected frequent combined self-care and were associated with sex, field of study, symptoms, prescription-related behavior, and treatment beliefs. Targeted health education may support more informed and rational self-care among university students.

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BibTeX
@article{almagableh2026herbal,
  title = {{Herbal or conventional medicine? A cross-sectional study of Jordanian university students’ preferences for cold and flu treatment}},
  author = {Mohammad Al-magableh and Abdulrhman H.M. Muhaisen and Rama M. Ateir and Shatha A. Abu_Eraq and Hanan O. Hamed and Sama M. Al Atoum and Reem Bani Amer and Soha S. AlShirah},
  journal = {PLOS One},
  year = {2026},
  month = sep,
  doi = {10.1371/journal.pone.0358179},
  url = {https://doi.org/10.1371/journal.pone.0358179},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Herbal or conventional medicine? A cross-sectional study of Jordanian university students’ preferences for cold and flu treatment
AU  - Mohammad Al-magableh
AU  - Abdulrhman H.M. Muhaisen
AU  - Rama M. Ateir
AU  - Shatha A. Abu_Eraq
AU  - Hanan O. Hamed
AU  - Sama M. Al Atoum
AU  - Reem Bani Amer
AU  - Soha S. AlShirah
PY  - 2026
DA  - 2026/09/15
JO  - PLOS One
DO  - 10.1371/journal.pone.0358179
UR  - https://doi.org/10.1371/journal.pone.0358179
AB  - Background: University students frequently self-manage common cold and influenza symptoms using herbal remedies, pharmaceutical treatments, or both. However, evidence regarding treatment preferences among Jordanian university students remains limited. Objective: To assess treatment preferences and factors associated with four outcomes: first-line treatment choice, timing of treatment initiation, response to perceived herbal treatment failure, and medication-obtaining behavior. Methods: An observational cross-sectional study was conducted in Jordan among 1,797 undergraduate students from 16 April to 16 September 2025 using a confidential, de-identified Arabic online questionnaire. Descriptive statistics and multinomial logistic regression were used to evaluate the four outcomes. Adjusted odds ratios (aORs) with 95% confidence intervals (CIs) were reported. Results: Combined therapy was the most common first-line choice (44.5%), and 42.5% initiated treatment on the same day. Female participants had higher odds of preferring combined therapy than males (aOR = 2.55, 95% CI: 1.64–3.96; p < 0.001), whereas medical-field students had lower odds of same-day treatment initiation (aOR = 0.55, 95% CI: 0.42–0.72; p < 0.001). After perceived herbal treatment failure, 50.7% switched to pharmaceutical treatments; reliance on doctor-prescribed treatments was associated with lower odds of continuing herbal remedies (aOR = 0.38, 95% CI: 0.27–0.51; p < 0.001) or combining herbal and pharmaceutical treatments (aOR = 0.56, 95% CI: 0.45–0.70; p < 0.001). Regarding medication-obtaining behavior, 28.2% purchased pharmaceutical treatments without a prescription based on personal experience, and medical-field students had higher odds of this behavior (aOR = 1.76, 95% CI: 1.39–2.23; p < 0.001). Conclusions: Treatment decisions reflected frequent combined self-care and were associated with sex, field of study, symptoms, prescription-related behavior, and treatment beliefs. Targeted health education may support more informed and rational self-care among university students.
SN  - 1932-6203
ER  -