Peer-reviewedCC BY-NC-ND中国当代儿科杂志
Evolution of treatment strategies and risk-stratified management of patent ductus arteriosus in preterm infants
- 1Department of Neonatal Intensive Care Unit, Children's Hospital, Zhejiang University School of Medicine/National Clinical Research Center for Children and Adolescents' Health and Diseases, Hangzhou 310052, China
Abstract
Patent ductus arteriosus is a common cardiovascular problem in preterm infants, particularly those born very preterm. Persistent left-to-right shunting may cause pulmonary overcirculation, left-sided volume overload, and systemic hypoperfusion, yet simply promoting anatomical ductal closure has not been shown to improve major clinical outcomes. Management has increasingly shifted from routine closure toward selective intervention guided by hemodynamic effects and clinical risk. This review summarizes the applicability of different management strategies, the boundaries of current evidence, and a risk-stratified management approach, providing reference for clinical decision-making and future research.
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BibTeX
@article{taixiang2026evolution,
title = {{Evolution of treatment strategies and risk-stratified management of patent ductus arteriosus in preterm infants}},
author = {LIU Tai-Xiang and SHI Li-Ping and CHEN Zheng},
journal = {中国当代儿科杂志},
year = {2026},
month = oct,
doi = {10.7499/j.issn.1008-8830.2606113},
url = {https://doi.org/10.7499/j.issn.1008-8830.2606113},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Evolution of treatment strategies and risk-stratified management of patent ductus arteriosus in preterm infants
AU - LIU Tai-Xiang
AU - SHI Li-Ping
AU - CHEN Zheng
PY - 2026
DA - 2026/10/23
JO - 中国当代儿科杂志
DO - 10.7499/j.issn.1008-8830.2606113
UR - https://doi.org/10.7499/j.issn.1008-8830.2606113
AB - Patent ductus arteriosus is a common cardiovascular problem in preterm infants, particularly those born very preterm. Persistent left-to-right shunting may cause pulmonary overcirculation, left-sided volume overload, and systemic hypoperfusion, yet simply promoting anatomical ductal closure has not been shown to improve major clinical outcomes. Management has increasingly shifted from routine closure toward selective intervention guided by hemodynamic effects and clinical risk. This review summarizes the applicability of different management strategies, the boundaries of current evidence, and a risk-stratified management approach, providing reference for clinical decision-making and future research.
SN - 1008-8830
SN - 2096-9228
ER -