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Peer-reviewedCC BYCureus

Anaesthetic Considerations for Twin Delivery in a Patient With Osteogenesis Imperfecta Type III: A Case Report.

  • Sneha E Eapen1
  • Bronte Bang Ting Jong2
  • Leonard Wei Wen Loh1
  1. 1Department of Anesthesiology, Singapore General Hospital, Singapore, SGP.
  2. 2Department of Anaesthesia, Ministry of Health, Singapore, SGP.
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Abstract

Osteogenesis imperfecta is an uncommon, inherited connective tissue disease, which is rare in pregnancy and presents multiple challenges to perinatal and anaesthetic care. Caesarean section in these patients is complex, often performed preterm and demands careful coordination between multiple disciplines. A 27-year-old woman at 26 weeks' gestation of a spontaneous twin pregnancy presented for elective caesarean section for worsening respiratory failure. General anaesthesia with total intravenous anaesthesia was used in view of anticipated prolonged surgery and difficult regional anaesthesia. The delivery was largely uneventful, and the patient recovered without major complications. The twins experienced multiple complications of prematurity. This case highlights the importance of multidisciplinary planning in achieving favourable maternal and foetal outcomes in high-risk pregnancies.

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Cite

BibTeXRIS
BibTeX
@article{eapen2026anaesthetic,
  title = {{Anaesthetic Considerations for Twin Delivery in a Patient With Osteogenesis Imperfecta Type III: A Case Report.}},
  author = {Sneha E Eapen and Bronte Bang Ting Jong and Leonard Wei Wen Loh},
  journal = {Cureus},
  year = {2026},
  month = oct,
  doi = {10.7759/cureus.118667},
  url = {https://europepmc.org/article/MED/42953519},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Anaesthetic Considerations for Twin Delivery in a Patient With Osteogenesis Imperfecta Type III: A Case Report.
AU  - Sneha E Eapen
AU  - Bronte Bang Ting Jong
AU  - Leonard Wei Wen Loh
PY  - 2026
DA  - 2026/10/27
JO  - Cureus
DO  - 10.7759/cureus.118667
UR  - https://europepmc.org/article/MED/42953519
AB  - Osteogenesis imperfecta is an uncommon, inherited connective tissue disease, which is rare in pregnancy and presents multiple challenges to perinatal and anaesthetic care. Caesarean section in these patients is complex, often performed preterm and demands careful coordination between multiple disciplines. A 27-year-old woman at 26 weeks' gestation of a spontaneous twin pregnancy presented for elective caesarean section for worsening respiratory failure. General anaesthesia with total intravenous anaesthesia was used in view of anticipated prolonged surgery and difficult regional anaesthesia. The delivery was largely uneventful, and the patient recovered without major complications. The twins experienced multiple complications of prematurity. This case highlights the importance of multidisciplinary planning in achieving favourable maternal and foetal outcomes in high-risk pregnancies.
SN  - 2168-8184
ER  -