Peer-reviewedCC BYProceedings of the National Academy of Sciences of the United States of America16 Oct 2026

Dystrophic changes of nigrostriatal axons harboring a SYNJ1 Parkinson’s mutation suggest catastrophic failure of endocytic mechanisms

Yumei Wu¹
Peng Xu¹
James Moran²
C. Shan Xu²
Kenneth J. Hayworth²
Mian Cao¹
Lin Shao²
D. James Surmeier²
Harald F. Hess²
Pietro De Camilli¹

¹Departments of Neuroscience and of Cell Biology, Program in Cellular Neuroscience, Neurodegeneration, and Repair and HHMI, Yale School of Medicine , ,
², ,

Reprogramming the gut–brain axis in neurodegeneration: comparative microbiome, metabolite, immunometabolic, polyphenol, probiotic, and epigenetic mechanisms in Alzheimer’s and Parkinson’s diseases
Yu Jie Cheng, Mei Ping Tao, Kexin Qian +1
Frontiers in Aging Neuroscience23 Oct 2026Peer-reviewedCC BYFull textMolecular biology & gene regulationDOAJ
Functional improvement of dystrophic muscle by utrophin gene editing
Trinath Ghosh, SK Tousif Ahamed, Junchao Xu +6
Molecular therapy. Advances1 Oct 2026Peer-reviewedCC BYFull textMolecular biology & gene regulationEurope PMCEurope PMCPMC
Anti–Receptor Activator of Nuclear Factor-κB Ligand Improves Muscle Dysfunction and Strengthens Bone in Laminin-α2–Deficient dy2J/dy2J Dystrophic Mice
Zineb Bouredji, Anthony Facchin, Dounia Hamoudi +5
American Journal of Pathology29 Oct 2026Peer-reviewedCC BY1 citedMolecular biology & gene regulationHAL
Melanoma of the Scalp Harboring a Novel AGFG1::ERBB4 Fusion: A Case Report With Clinicopathologic and Genomic Characterization.
Xu Cao, Hong Yu, Kenneth L Muldrew +6
Genes, chromosomes & cancer1 Oct 2026Peer-reviewedCC BYFull textMolecular biology & gene regulationEurope PMCPMC
Mitochondrial protein import stress in Parkinson’s disease: the TOM/TIM–PINK1/Parkin–DELE1/HRI axis linking mitochondrial proteostasis to neuronal death
Bo Pang, Xin Li, Yunlong Sun +1
Frontiers in cell and developmental biology16 Oct 2026Peer-reviewedCC BYFull textGeneral biochemistryEurope PMC

Cite

BibTeX

@article{wu2026dystrophic,
  title = {{Dystrophic changes of nigrostriatal axons harboring a SYNJ1 Parkinson’s mutation suggest catastrophic failure of endocytic mechanisms}},
  author = {Yumei Wu and Peng Xu and James Moran and C. Shan Xu and Kenneth J. Hayworth and Mian Cao and Lin Shao and D. James Surmeier and Harald F. Hess and Pietro De Camilli},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year = {2026},
  month = oct,
  url = {https://europepmc.org/article/PMC/PMC13663811},
  note = {CC BY},
}

RIS

TY  - JOUR
TI  - Dystrophic changes of nigrostriatal axons harboring a SYNJ1 Parkinson’s mutation suggest catastrophic failure of endocytic mechanisms
AU  - Yumei Wu
AU  - Peng Xu
AU  - James Moran
AU  - C. Shan Xu
AU  - Kenneth J. Hayworth
AU  - Mian Cao
AU  - Lin Shao
AU  - D. James Surmeier
AU  - Harald F. Hess
AU  - Pietro De Camilli
PY  - 2026
DA  - 2026/10/16
JO  - Proceedings of the National Academy of Sciences of the United States of America
UR  - https://europepmc.org/article/PMC/PMC13663811
SN  - 0027-8424
SN  - 1091-6490
ER  -

Related

Cite