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Peer-reviewedCC BY-NC-NDThe Japanese dental science review

Laser-assisted remineralization of dental hard tissues: A scoping review.

  1. 1Department of Restorative Dentistry, Faculty of Dentistry, Ordu University, Ordu, Türkiye.
  2. 2Department of Restorative Dentistry, Faculty of Dentistry, Antalya Bilim University, Antalya, Türkiye.
  3. 3Department of Periodontology, Faculty of Dentistry, Antalya Bilim University, Antalya, Türkiye.

Abstract

The non-invasive management of early carious lesions has increased the clinical importance of remineralization strategies. This scoping review aims to comprehensively map the laser systems, remineralizing agents, application protocols, and reported efficacy outcomes in laser-assisted remineralization. A literature search was conducted on March 15, 2026, in PubMed, Scopus, and Web of Science. English full-text original studies investigating laser-assisted remineralization were screened, and reference lists were hand-searched. The review was conducted in accordance with JBI methodology and the PRISMA-ScR guideline. A total of 41 studies published between 2016 and 2026 that met the inclusion criteria were included. Peer-reviewed English full-text original studies evaluating laser-agent combinations in in vitro and clinical settings were included, while reviews, case reports, animal studies, and studies with unclear protocols were excluded. The effectiveness of laser-assisted remineralization varies depending on the laser type, agent type, and application sequence. CO₂ and Er:YAG lasers were most commonly used in combination with fluoride and CPP-ACP agents. However, the predominance of in vitro studies and methodological heterogeneity may limit the clinical generalizability of the findings.

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BibTeX
@article{ozyilmaz2026laserassisted,
  title = {{Laser-assisted remineralization of dental hard tissues: A scoping review.}},
  author = {Hatice Ozyilmaz and Beyza Dalkilic and Barış Ufuk Dalkilic},
  journal = {The Japanese dental science review},
  year = {2026},
  month = oct,
  doi = {10.1016/j.jdsr.2026.10.002},
  url = {https://europepmc.org/article/MED/42999681},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Laser-assisted remineralization of dental hard tissues: A scoping review.
AU  - Hatice Ozyilmaz
AU  - Beyza Dalkilic
AU  - Barış Ufuk Dalkilic
PY  - 2026
DA  - 2026/10/30
JO  - The Japanese dental science review
DO  - 10.1016/j.jdsr.2026.10.002
UR  - https://europepmc.org/article/MED/42999681
AB  - The non-invasive management of early carious lesions has increased the clinical importance of remineralization strategies. This scoping review aims to comprehensively map the laser systems, remineralizing agents, application protocols, and reported efficacy outcomes in laser-assisted remineralization. A literature search was conducted on March 15, 2026, in PubMed, Scopus, and Web of Science. English full-text original studies investigating laser-assisted remineralization were screened, and reference lists were hand-searched. The review was conducted in accordance with JBI methodology and the PRISMA-ScR guideline. A total of 41 studies published between 2016 and 2026 that met the inclusion criteria were included. Peer-reviewed English full-text original studies evaluating laser-agent combinations in in vitro and clinical settings were included, while reviews, case reports, animal studies, and studies with unclear protocols were excluded. The effectiveness of laser-assisted remineralization varies depending on the laser type, agent type, and application sequence. CO₂ and Er:YAG lasers were most commonly used in combination with fluoride and CPP-ACP agents. However, the predominance of in vitro studies and methodological heterogeneity may limit the clinical generalizability of the findings.
SN  - 1882-7616
SN  - 2213-6851
ER  -