How Effective Is Saline Solution Infiltration During Coaxial Needle Withdrawal in Reducing the Incidence of Pneumothorax in CT-Guided Lung Biopsies?
- 1University Hospital of Parma, Via Gramsci 14, 43126 Parma, PR, Italy.
- 2Areteion Hospital, National and Kapodistrian University of Athens, 76, Vas. Sophias Ave, 11528 Athens, Greece.
Abstract
Background/Objectives: This study evaluates whether saline infiltration during coaxial needle withdrawal reduces the incidence of pneumothorax (PTX) in CT-guided lung biopsies, potentially enhancing procedural safety. Methods: A retrospective analysis of 200 consecutive CT-guided core needle biopsies (18G) was conducted using our hospital's Radiology Department database. All procedures were performed between February 2022 and December 2024 by a single operator with 20 years of experience. Patients were divided into two groups: Group A (100 patients), receiving 10 mL of 0.9% saline solution during coaxial needle withdrawal, and Group B (100 patients), in whom no saline was infiltrated. Descriptive and inferential statistical analyses were used to assess the relationship between saline infiltration and the incidence of PTX. Results: PTX occurred in 24% of Group B patients versus 7% in Group A (p = 0.001). Multivariate analysis identified saline infiltration as a significant protective factor, even in high-risk patients (e.g., those with emphysema or in lateral decubitus). The odds ratio (OR = 0.18; 95% CI: 0.07-0.48) indicates that saline infiltration significantly reduces the risk of PTX. Conclusions: Infiltration of 10 mL of saline during coaxial needle withdrawal significantly reduces the incidence of PTX in CT-guided lung biopsies, offering a simple and effective strategy to enhance patient safety.
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BibTeX
@article{viviano2026effective,
title = {{How Effective Is Saline Solution Infiltration During Coaxial Needle Withdrawal in Reducing the Incidence of Pneumothorax in CT-Guided Lung Biopsies?}},
author = {Giulia Viviano and Ganyat Adenike Ralitsa Adebanjo and Giorgio Concari and Chiara Martini and Giuseppe Pedrazzi and Miltos Krokidis and Massimo De Filippo},
journal = {Diagnostics (Basel, Switzerland)},
year = {2026},
month = sep,
doi = {10.3390/diagnostics16193080},
url = {https://europepmc.org/article/MED/42882235},
note = {CC BY},
}
RIS
TY - JOUR
TI - How Effective Is Saline Solution Infiltration During Coaxial Needle Withdrawal in Reducing the Incidence of Pneumothorax in CT-Guided Lung Biopsies?
AU - Giulia Viviano
AU - Ganyat Adenike Ralitsa Adebanjo
AU - Giorgio Concari
AU - Chiara Martini
AU - Giuseppe Pedrazzi
AU - Miltos Krokidis
AU - Massimo De Filippo
PY - 2026
DA - 2026/09/22
JO - Diagnostics (Basel, Switzerland)
DO - 10.3390/diagnostics16193080
UR - https://europepmc.org/article/MED/42882235
AB - Background/Objectives: This study evaluates whether saline infiltration during coaxial needle withdrawal reduces the incidence of pneumothorax (PTX) in CT-guided lung biopsies, potentially enhancing procedural safety. Methods: A retrospective analysis of 200 consecutive CT-guided core needle biopsies (18G) was conducted using our hospital's Radiology Department database. All procedures were performed between February 2022 and December 2024 by a single operator with 20 years of experience. Patients were divided into two groups: Group A (100 patients), receiving 10 mL of 0.9% saline solution during coaxial needle withdrawal, and Group B (100 patients), in whom no saline was infiltrated. Descriptive and inferential statistical analyses were used to assess the relationship between saline infiltration and the incidence of PTX. Results: PTX occurred in 24% of Group B patients versus 7% in Group A (p = 0.001). Multivariate analysis identified saline infiltration as a significant protective factor, even in high-risk patients (e.g., those with emphysema or in lateral decubitus). The odds ratio (OR = 0.18; 95% CI: 0.07-0.48) indicates that saline infiltration significantly reduces the risk of PTX. Conclusions: Infiltration of 10 mL of saline during coaxial needle withdrawal significantly reduces the incidence of PTX in CT-guided lung biopsies, offering a simple and effective strategy to enhance patient safety.
SN - 2075-4418
ER -