PreprintAll rights reservedbioRxiv
An age-preserving neuronal iSpheroid platform for modeling human aging and Alzheimer disease
- 1Salk Institute for Biological Studies
Related
- Aberrant neuronal cell cycle re-entry induces late-onset Alzheimer's disease relevant neuropathological and gene expression changes
- AAV-DJ enables efficient, function-preserving neuronal transduction for circuit interrogation in human cortical and thalamic organoids
- Autolysosomal acidification impairment as a mediator for TNFR1 induced neuronal necroptosis in Alzheimer's disease
- Single-Nucleus Profiling Reveals Neuronal Metabolic Collapse During the Transition to Alzheimer's Disease Dementia
- BNIP3L/NIX-mediated mitophagy limits Alzheimer disease pathology and preserves neuronal function
BibTeX
@misc{alsolami2026agepreserving,
title = {{An age-preserving neuronal iSpheroid platform for modeling human aging and Alzheimer disease}},
author = {S. Alsolami and M. Wang and T. Sarraf Sabedot and U. Singh and B. Kirk and L. Mitchell and M. Hernandez and N. Skvir and C. Bowman and K. Oiwa and R. Agarwal and M. Mahmoudi and M. S. Cuoco and E. MacDonald and S. Cranston and R. Lucciola and D. Boassa and J. R. Herdy and J. R. Jones and K. Yoshikiyo and J. Mertens and J. Martinez-Trujillo and L. Jaremko and G. J. Murphy and F. H. Gage},
howpublished = {bioRxiv},
year = {2026},
month = sep,
doi = {10.64898/2026.09.30.755853},
url = {https://www.biorxiv.org/content/10.64898/2026.09.30.755853v1},
}
RIS
TY - UNPB
TI - An age-preserving neuronal iSpheroid platform for modeling human aging and Alzheimer disease
AU - S. Alsolami
AU - M. Wang
AU - T. Sarraf Sabedot
AU - U. Singh
AU - B. Kirk
AU - L. Mitchell
AU - M. Hernandez
AU - N. Skvir
AU - C. Bowman
AU - K. Oiwa
AU - R. Agarwal
AU - M. Mahmoudi
AU - M. S. Cuoco
AU - E. MacDonald
AU - S. Cranston
AU - R. Lucciola
AU - D. Boassa
AU - J. R. Herdy
AU - J. R. Jones
AU - K. Yoshikiyo
AU - J. Mertens
AU - J. Martinez-Trujillo
AU - L. Jaremko
AU - G. J. Murphy
AU - F. H. Gage
PY - 2026
DA - 2026/09/30
PB - bioRxiv
DO - 10.64898/2026.09.30.755853
UR - https://www.biorxiv.org/content/10.64898/2026.09.30.755853v1
ER -