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Peer-reviewedCC BY 4.0Frontiers in Reproductive Health

Case Report: Monochorionic triamniotic triplet pregnancy following single vitrified-warmed blastocyst transfer

  • Artem A. Aksenenko1
  • Tatyana A. Kodyleva1
  • Polina O. Patskova1
  • Alla A. Gavisova1
  • Gennadiy T. Sukhikh2
  1. 1Department of Preservation and Restoration of Reproductive Function, National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov, Ministry of Health of the Russian Federation, Moscow, Russia
  2. 2National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov, Ministry of Health of the Russian Federation, Moscow, Russia
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Abstract

Monochorionic triamniotic triplet pregnancy following single embryo transfer is an exceptionally rare outcome of assisted reproductive technology. We report a monochorionic triamniotic triplet pregnancy following transfer of a single vitrified-warmed blastocyst. Fertilization was performed by intracytoplasmic sperm injection, with no assisted hatching, trophectoderm biopsy or preimplantation genetic testing. Initial transvaginal ultrasound 21 days after embryo transfer demonstrated a singleton intrauterine pregnancy. At 8 weeks and 1 day of gestation, three viable embryos were identified within a monochorionic triamniotic pregnancy. The pregnancy remained uncomplicated, with appropriate growth of all three fetuses, and three live female infants were delivered at 35 weeks of gestation. This case adds to the limited number of reported monochorionic triamniotic triplet pregnancies following single embryo transfer and is distinguished by transfer of a day-6 vitrified-warmed blastocyst that re-expanded from grade 2BB after warming to 6BB before transfer, without assisted hatching, trophectoderm biopsy or preimplantation genetic testing.

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Cite

BibTeXRIS
BibTeX
@article{aksenenko2026case,
  title = {{Case Report: Monochorionic triamniotic triplet pregnancy following single vitrified-warmed blastocyst transfer}},
  author = {Artem A. Aksenenko and Tatyana A. Kodyleva and Polina O. Patskova and Alla A. Gavisova and Gennadiy T. Sukhikh},
  journal = {Frontiers in Reproductive Health},
  year = {2026},
  month = oct,
  doi = {10.3389/frph.2026.1977805},
  url = {https://doi.org/10.3389/frph.2026.1977805},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Case Report: Monochorionic triamniotic triplet pregnancy following single vitrified-warmed blastocyst transfer
AU  - Artem A. Aksenenko
AU  - Tatyana A. Kodyleva
AU  - Polina O. Patskova
AU  - Alla A. Gavisova
AU  - Gennadiy T. Sukhikh
PY  - 2026
DA  - 2026/10/12
JO  - Frontiers in Reproductive Health
DO  - 10.3389/frph.2026.1977805
UR  - https://doi.org/10.3389/frph.2026.1977805
AB  - Monochorionic triamniotic triplet pregnancy following single embryo transfer is an exceptionally rare outcome of assisted reproductive technology. We report a monochorionic triamniotic triplet pregnancy following transfer of a single vitrified-warmed blastocyst. Fertilization was performed by intracytoplasmic sperm injection, with no assisted hatching, trophectoderm biopsy or preimplantation genetic testing. Initial transvaginal ultrasound 21 days after embryo transfer demonstrated a singleton intrauterine pregnancy. At 8 weeks and 1 day of gestation, three viable embryos were identified within a monochorionic triamniotic pregnancy. The pregnancy remained uncomplicated, with appropriate growth of all three fetuses, and three live female infants were delivered at 35 weeks of gestation. This case adds to the limited number of reported monochorionic triamniotic triplet pregnancies following single embryo transfer and is distinguished by transfer of a day-6 vitrified-warmed blastocyst that re-expanded from grade 2BB after warming to 6BB before transfer, without assisted hatching, trophectoderm biopsy or preimplantation genetic testing.
SN  - 2673-3153
ER  -