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Peer-reviewedLicence not statedGenetics in medicine : official journal of the American College of Medical Genetics

Implementing a Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease in a Diverse Cohort

  • Marwan Hamed1
  • Mohammadreza Naderian1
  • Hana Bangash1
  • Valentina Hernandez2
  • Gabriel Q. Shaibi3
  • Meliksah Arslan1
  • Seyedmohammad Saadatagah1
  • Alborz Sherafati1
  • Alexandra Miller1
  • Arailym Kamzabek1
  • Oluwateniayo Ogunsan1
  • Blake Goff4
18 more authors
  • Brittney Davis4
  • Cynthia Prows5
  • James J. Cimino6
  • Josh Cortopassi6
  • Leah Kottyan5
  • Mark Beasley7
  • Nita Limdi6
  • Qiping Feng8
  • Robb Rowley9
  • Sharice Wood10
  • Wei-Qi Wei8
  • Yuan Luo11
  • Teri A. Manolio9
  • Daniel Schaid12
  • Pedro J. Caraballo13
  • Robert Freimuth14,15
  • Richard R. Sharp15,16
  • Iftikhar J. Kullo17
17 affiliations
  1. 1Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA
  2. 2Mountain Park Health Center, Phoenix, AZ, USA
  3. 3Center for Health Promotion and Disease Prevention, Arizona State University, Phoenix, AZ, USA
  4. 4Department of Neurology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
  5. 5Divisions of Human Genetics and Patient Services, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA
  6. 6Department of Biomedical Informatics and Data Science, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
  7. 7Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA
  8. 8Department of Biomedical Informatics and Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
  9. 9National Human Genome Research Institute, Division of Genomic Medicine, Bethesda, MD, USA.
  10. 10The Center for Autoimmune Genomics and Etiology, Division of Human Genetics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA
  11. 11Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
  12. 12Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA
  13. 13Department of Medicine, Mayo Clinic, Rochester, MN, USA
  14. 14Department of Artificial Intelligence and Informatics, Mayo Clinic, Rochester, MN, USA
  15. 15Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA
  16. 16Biomedical Ethics Research Program, Mayo Clinic, Rochester, MN, USA
  17. 17Division of Cardiovascular Medicine, the Cardiovascular Research Center and the Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
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Cite

BibTeXRIS
BibTeX
@article{hamed2026implementing,
  title = {{Implementing a Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease in a Diverse Cohort}},
  author = {Marwan Hamed and Mohammadreza Naderian and Hana Bangash and Valentina Hernandez and Gabriel Q. Shaibi and Meliksah Arslan and Seyedmohammad Saadatagah and Alborz Sherafati and Alexandra Miller and Arailym Kamzabek and Oluwateniayo Ogunsan and Blake Goff and Brittney Davis and Cynthia Prows and James J. Cimino and Josh Cortopassi and Leah Kottyan and Mark Beasley and Nita Limdi and Qiping Feng and Robb Rowley and Sharice Wood and Wei-Qi Wei and Yuan Luo and Teri A. Manolio and Daniel Schaid and Pedro J. Caraballo and Robert Freimuth and Richard R. Sharp and Iftikhar J. Kullo},
  journal = {Genetics in medicine : official journal of the American College of Medical Genetics},
  year = {2026},
  month = jul,
  doi = {10.1016/j.gim.2026.102662},
  url = {https://doi.org/10.1016/j.gim.2026.102662},
}
RIS
TY  - JOUR
TI  - Implementing a Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease in a Diverse Cohort
AU  - Marwan Hamed
AU  - Mohammadreza Naderian
AU  - Hana Bangash
AU  - Valentina Hernandez
AU  - Gabriel Q. Shaibi
AU  - Meliksah Arslan
AU  - Seyedmohammad Saadatagah
AU  - Alborz Sherafati
AU  - Alexandra Miller
AU  - Arailym Kamzabek
AU  - Oluwateniayo Ogunsan
AU  - Blake Goff
AU  - Brittney Davis
AU  - Cynthia Prows
AU  - James J. Cimino
AU  - Josh Cortopassi
AU  - Leah Kottyan
AU  - Mark Beasley
AU  - Nita Limdi
AU  - Qiping Feng
AU  - Robb Rowley
AU  - Sharice Wood
AU  - Wei-Qi Wei
AU  - Yuan Luo
AU  - Teri A. Manolio
AU  - Daniel Schaid
AU  - Pedro J. Caraballo
AU  - Robert Freimuth
AU  - Richard R. Sharp
AU  - Iftikhar J. Kullo
PY  - 2026
DA  - 2026/07/11
JO  - Genetics in medicine : official journal of the American College of Medical Genetics
DO  - 10.1016/j.gim.2026.102662
UR  - https://doi.org/10.1016/j.gim.2026.102662
SN  - 1098-3600
SN  - 1530-0366
ER  -