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Peer-reviewedLicence not statedPhenomics

Artificial Avidity Optimization of T-cell Receptors by Integrating Deep Learning Model and Mammalian Cell Surface Display

  • Mengmeng Wei1,2
  • Shengzuo Bai1,3
  • Wenfan Chen4
  • Jingcheng Wu5
  • Yi Pan1
  • Wenyi Zhao3
  • Wenhui Qian1
  • Ji Cao1,3
  • Gang Pan2
  • Xueli Bai6
  • Ruhong Zhou4
  • Wenbin Zhao1,3
2 more authors
  • Shuqing Chen1
  • Zhan Zhou1,3,7
7 affiliations
  1. 1State Key Laboratory of Advanced Drug Delivery and Release Systems & Zhejiang Provincial Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058 China
  2. 2Collaborative Innovation Center of Artificial Intelligence By MOE and Zhejiang Provincial Government, College of Computer Science and Technology, Zhejiang University, Hangzhou, 310027 China
  3. 3Innovation Institute for Artificial Intelligence in Medicine & MOE Engineering Research Center of Innovative Anticancer Drugs, Zhejiang University, Hangzhou, 310018 China
  4. 4Institute of Quantitative Biology, College of Life Sciences, Zhejiang University, Hangzhou, 310058 China
  5. 5Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Department of Clinical Pharmacology, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou, 310006 China
  6. 6Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003 China
  7. 7The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, 322000 China
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Cite

BibTeXRIS
BibTeX
@article{wei2026artificial,
  title = {{Artificial Avidity Optimization of T-cell Receptors by Integrating Deep Learning Model and Mammalian Cell Surface Display}},
  author = {Mengmeng Wei and Shengzuo Bai and Wenfan Chen and Jingcheng Wu and Yi Pan and Wenyi Zhao and Wenhui Qian and Ji Cao and Gang Pan and Xueli Bai and Ruhong Zhou and Wenbin Zhao and Shuqing Chen and Zhan Zhou},
  journal = {Phenomics},
  year = {2026},
  month = jun,
  doi = {10.1007/s43657-025-00295-w},
  url = {https://doi.org/10.1007/s43657-025-00295-w},
}
RIS
TY  - JOUR
TI  - Artificial Avidity Optimization of T-cell Receptors by Integrating Deep Learning Model and Mammalian Cell Surface Display
AU  - Mengmeng Wei
AU  - Shengzuo Bai
AU  - Wenfan Chen
AU  - Jingcheng Wu
AU  - Yi Pan
AU  - Wenyi Zhao
AU  - Wenhui Qian
AU  - Ji Cao
AU  - Gang Pan
AU  - Xueli Bai
AU  - Ruhong Zhou
AU  - Wenbin Zhao
AU  - Shuqing Chen
AU  - Zhan Zhou
PY  - 2026
DA  - 2026/06/17
JO  - Phenomics
DO  - 10.1007/s43657-025-00295-w
UR  - https://doi.org/10.1007/s43657-025-00295-w
SN  - 2730-583X
SN  - 2730-5848
ER  -