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Reducing Hydrocephalus Shunt Revision Rates: A Computational Fluid Dynamics Study on Catheter Hole Design

Abstract

Proximal shunt obstruction is the leading cause of ventriculoperitoneal (VP) shunt failure in pediatric hydrocephalus and is closely tied to the near-wall shear environment at drainage holes. We used computational fluid dynamics (COMSOL) to decouple local wall-shear-stress (WSS) control via catheter-tip geometry from global drainage control via a valve opening. A cylindrical ventricle domain with Newtonian CSF (ρ = 1000 kg/m3, μ = 1 mPa·s) and ΔP ≈ 10 mmHg was solved under laminar Navier-Stokes flow while sweeping distal hole spacing, hole count/diameter, and a simplified valve constriction. Mesh-independence was achieved (minimum element size ≈ 0.021 mm; distal-hole velocity converged to ≈ 1.18×10−3 m/s). Perpendicular separation of the two most distal holes increased total outflow by ≈ 22% (2 mm vs 0.5 mm) and raised distal lateral-wall WSS by ≈ 19%, whereas longitudinal shifts of upstream holes produced only small changes. A valve opening near 0.166-0.17 mm set system drainage to ≈ 20 mL/h across geometries, indicating capacity is valve-limited while local WSS is geometry-controlled. The selected tip uses two conical holes (0.5 mm ID) in four rows with 1.4 mm spacing, concentrating WSS at the distal lateral walls, the surfaces where obstruction occurs, without exceeding clinical drainage targets. These findings yield design rules: prioritize distal-pair spacing, reduce hole count with smaller conical openings to elevate protective WSS, and regulate outflow with the valve. The framework provides a clear path to benchtop validation, long-term adhesion assays under mapped WSS, and anatomically realistic CFD.

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BibTeX
@misc{said2026reducing,
  title = {{Reducing Hydrocephalus Shunt Revision Rates: A Computational Fluid Dynamics Study on Catheter Hole Design}},
  author = {Omar Said and Mingzi Li and Hanyu Gan},
  howpublished = {arXiv},
  year = {2026},
  month = sep,
  doi = {10.48550/arxiv.2609.08030},
  eprint = {2609.08030},
  archivePrefix = {arXiv},
  url = {https://arxiv.org/abs/2609.08030},
}
RIS
TY  - UNPB
TI  - Reducing Hydrocephalus Shunt Revision Rates: A Computational Fluid Dynamics Study on Catheter Hole Design
AU  - Omar Said
AU  - Mingzi Li
AU  - Hanyu Gan
PY  - 2026
DA  - 2026/09/07
PB  - arXiv
DO  - 10.48550/arxiv.2609.08030
UR  - https://arxiv.org/abs/2609.08030
AB  - Proximal shunt obstruction is the leading cause of ventriculoperitoneal (VP) shunt failure in pediatric hydrocephalus and is closely tied to the near-wall shear environment at drainage holes. We used computational fluid dynamics (COMSOL) to decouple local wall-shear-stress (WSS) control via catheter-tip geometry from global drainage control via a valve opening. A cylindrical ventricle domain with Newtonian CSF (ρ = 1000 kg/m^3, μ = 1 mPa·s) and ΔP ≈ 10 mmHg was solved under laminar Navier-Stokes flow while sweeping distal hole spacing, hole count/diameter, and a simplified valve constriction. Mesh-independence was achieved (minimum element size ≈ 0.021 mm; distal-hole velocity converged to ≈ 1.18×10^−3 m/s). Perpendicular separation of the two most distal holes increased total outflow by ≈ 22% (2 mm vs 0.5 mm) and raised distal lateral-wall WSS by ≈ 19%, whereas longitudinal shifts of upstream holes produced only small changes. A valve opening near 0.166-0.17 mm set system drainage to ≈ 20 mL/h across geometries, indicating capacity is valve-limited while local WSS is geometry-controlled. The selected tip uses two conical holes (0.5 mm ID) in four rows with 1.4 mm spacing, concentrating WSS at the distal lateral walls, the surfaces where obstruction occurs, without exceeding clinical drainage targets. These findings yield design rules: prioritize distal-pair spacing, reduce hole count with smaller conical openings to elevate protective WSS, and regulate outflow with the valve. The framework provides a clear path to benchtop validation, long-term adhesion assays under mapped WSS, and anatomically realistic CFD.
ER  -