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Peer-reviewedCC BYClinical Case Reports

Mixed Neuroendocrine—Non‐Neuroendocrine Neoplasm (MiNEN) of the Gallbladder. A Case Report From a Low‐Resource Setting

  • Muhammad Farhan1
  • Muhammad Imran1
  • Beenish Sabir2
  • Khalil Ahmad1
  • Farheen Khan1
  • Shahid Hussain1
  • Zohaib Ahmed1
  • Muhammad Asim1
  • Iqra Mehmood3
  • Rahmat Gul Omarzai4
4 affiliations
  1. 1Department of General Surgery Shaheed Saif Ur Rehman Government Teaching Hospital Gilgit Pakistan
  2. 2Rawalpindi Medical University Rawalpindi Pakistan
  3. 3Department of Histopathology Shifa International Hospital Islamabad Pakistan
  4. 4Department of Medicine Nangarhar University Daronta, Nangarhar Afghanistan
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Abstract

Mixed neuroendocrine–non‐neuroendocrine neoplasms (MiNENs) of the gallbladder are exceedingly rare entities. We report a case of a 35‐year‐old female with a palpable right hypochondrial mass. Imaging demonstrated a large polypoid gallbladder lesion with periportal lymphadenopathy. The patient underwent open cholecystectomy with lymphadenectomy. Histopathology and immunohistochemistry revealed a MiNEN. At 12‐month follow‐up, she remained free of recurrence without any adjuvant chemotherapy.

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Cite

BibTeXRIS
BibTeX
@article{farhan2026mixed,
  title = {{Mixed Neuroendocrine—Non‐Neuroendocrine Neoplasm (MiNEN) of the Gallbladder. A Case Report From a Low‐Resource Setting}},
  author = {Muhammad Farhan and Muhammad Imran and Beenish Sabir and Khalil Ahmad and Farheen Khan and Shahid Hussain and Zohaib Ahmed and Muhammad Asim and Iqra Mehmood and Rahmat Gul Omarzai},
  journal = {Clinical Case Reports},
  year = {2026},
  month = oct,
  doi = {10.1002/ccr3.73652},
  url = {https://doi.org/10.1002/ccr3.73652},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Mixed Neuroendocrine—Non‐Neuroendocrine Neoplasm (MiNEN) of the Gallbladder. A Case Report From a Low‐Resource Setting
AU  - Muhammad Farhan
AU  - Muhammad Imran
AU  - Beenish Sabir
AU  - Khalil Ahmad
AU  - Farheen Khan
AU  - Shahid Hussain
AU  - Zohaib Ahmed
AU  - Muhammad Asim
AU  - Iqra Mehmood
AU  - Rahmat Gul Omarzai
PY  - 2026
DA  - 2026/10/23
JO  - Clinical Case Reports
DO  - 10.1002/ccr3.73652
UR  - https://doi.org/10.1002/ccr3.73652
AB  - Mixed neuroendocrine–non‐neuroendocrine neoplasms (MiNENs) of the gallbladder are exceedingly rare entities. We report a case of a 35‐year‐old female with a palpable right hypochondrial mass. Imaging demonstrated a large polypoid gallbladder lesion with periportal lymphadenopathy. The patient underwent open cholecystectomy with lymphadenectomy. Histopathology and immunohistochemistry revealed a MiNEN. At 12‐month follow‐up, she remained free of recurrence without any adjuvant chemotherapy.
SN  - 2050-0904
ER  -