Comparison of Visual and Ocular Hemodynamic Outcomes Following Trifocal vs Bifocal Intraocular Lens Implantation in Patients With Cataract and Myopia.
4 affiliations
- 1Department of Ophthalmology, Xi'an People's Hospital (Xi'an Fourth Hospital), Xi'an, Shaanxi, China.
- 2Seventh Department of Recuperation, Dalian Rehabilitation and Recuperation Center, Dalian, Liaoning, China.
- 3Department of Ophthalmology, Sichuan Provincial Judicial Police General Hospital, Chengdu, Sichuan, China.
- 4Department of Ophthalmology, Shangluo Hospital of Traditional Chinese Medicine, Shangluo, Shaanxi, China.
Abstract
BACKGROUND This retrospective study from a single center aimed to compare postoperative visual, structural, and ocular hemodynamic outcomes following implantation of a trifocal intraocular lens (IOL) in 67 patients and a bifocal IOL in 67 patients with combined cataract and myopia. MATERIAL AND METHODS A total of 134 patients (268 eyes) with cataract and myopia treated between June 2022 and June 2024 were retrospectively analyzed and divided into a bifocal IOL group (n=67; 134 eyes) and a trifocal IOL group (n=67; 134 eyes). All patients underwent standardized phacoemulsification with capsular bag IOL implantation and were evaluated 6 months postoperatively. Outcomes included visual acuity, intraocular pressure, anterior chamber depth, axial length, lens thickness, mean blood flow density, pulsatility index, and resistance index. Generalized estimating equation models were used to account for inter-eye correlation. RESULTS Compared with the bifocal IOL group, the trifocal IOL group showed lower postoperative intraocular pressure (P=0.003) and anterior chamber depth (P=0.004) and improved oculus dexter visual acuity (P=0.003). Lens thickness was lower postoperatively, whereas axial length remained stable between groups. Mean blood flow density increased (P=0.020), whereas pulsatility index (P=0.003) and resistance index (P=0.002) decreased. Adverse events were less frequent in the trifocal IOL group (P=0.029). However, the observed differences were modest, with uncertain clinical significance. CONCLUSIONS Trifocal IOL implantation was associated with limited postoperative differences in visual and hemodynamic outcomes compared with bifocal IOL implantation. These findings require cautious interpretation and validation in larger prospective studies with longer follow-up.
Related
- Three-Year Functional Vision, Longitudinal Refractive Outcomes, and Patient-Reported Outcomes After Bilateral Implantation of the Extend Bessel-Optics Intraocular Lens: An Independent Real-World Ambispective Study
- Effect of Residual Astigmatism on Visual Acuity Following Bifocal, Trifocal, and Extended Depth-of-Focus Intraocular Lens Implantation: A Retrospective Cohort Study
- Effect of residual spherical equivalent on visual outcomes of trifocal intraocular lens implantation in patients with cataracts across different refractive states
- Comparison of the Effects of 0.05% Difluprednate Ophthalmic Solution and 1% Prednisolone Acetate Ophthalmic Solution on Intraocular Inflammation Following Lens Surgery in Healthy Rabbits.
- Impact of prolonged balloon inflation on valve expansion and early clinical outcomes following contemporary balloon-expandable transcatheter aortic valve implantation
BibTeX
@article{xu2026comparison,
title = {{Comparison of Visual and Ocular Hemodynamic Outcomes Following Trifocal vs Bifocal Intraocular Lens Implantation in Patients With Cataract and Myopia.}},
author = {Man Xu and Yan Shao and Xing Gao and Qilin Wu},
journal = {Medical science monitor : international medical journal of experimental and clinical research},
year = {2026},
month = oct,
doi = {10.12659/msm.953476},
url = {https://europepmc.org/article/MED/42885119},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Comparison of Visual and Ocular Hemodynamic Outcomes Following Trifocal vs Bifocal Intraocular Lens Implantation in Patients With Cataract and Myopia.
AU - Man Xu
AU - Yan Shao
AU - Xing Gao
AU - Qilin Wu
PY - 2026
DA - 2026/10/16
JO - Medical science monitor : international medical journal of experimental and clinical research
DO - 10.12659/msm.953476
UR - https://europepmc.org/article/MED/42885119
AB - BACKGROUND This retrospective study from a single center aimed to compare postoperative visual, structural, and ocular hemodynamic outcomes following implantation of a trifocal intraocular lens (IOL) in 67 patients and a bifocal IOL in 67 patients with combined cataract and myopia. MATERIAL AND METHODS A total of 134 patients (268 eyes) with cataract and myopia treated between June 2022 and June 2024 were retrospectively analyzed and divided into a bifocal IOL group (n=67; 134 eyes) and a trifocal IOL group (n=67; 134 eyes). All patients underwent standardized phacoemulsification with capsular bag IOL implantation and were evaluated 6 months postoperatively. Outcomes included visual acuity, intraocular pressure, anterior chamber depth, axial length, lens thickness, mean blood flow density, pulsatility index, and resistance index. Generalized estimating equation models were used to account for inter-eye correlation. RESULTS Compared with the bifocal IOL group, the trifocal IOL group showed lower postoperative intraocular pressure (P=0.003) and anterior chamber depth (P=0.004) and improved oculus dexter visual acuity (P=0.003). Lens thickness was lower postoperatively, whereas axial length remained stable between groups. Mean blood flow density increased (P=0.020), whereas pulsatility index (P=0.003) and resistance index (P=0.002) decreased. Adverse events were less frequent in the trifocal IOL group (P=0.029). However, the observed differences were modest, with uncertain clinical significance. CONCLUSIONS Trifocal IOL implantation was associated with limited postoperative differences in visual and hemodynamic outcomes compared with bifocal IOL implantation. These findings require cautious interpretation and validation in larger prospective studies with longer follow-up.
SN - 1234-1010
SN - 1643-3750
ER -