Peer-reviewedCC BYJournal of Clinical Medicine Research
Cytochrome P450 2D6 Metabolizer Phenotype Is Associated With Metoprolol Pharmacodynamics But Not With Metoprolol Discontinuation: A Retrospective Cohort Study in the All of Us Research Program
13 affiliations
- 1Department of Neurology, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, FL, USA
- 2Department of Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA
- 3Department of Medicine, PDU Medical College, Rajkot, Gujarat, India
- 4Department of Medicine, GMERS Medical College, Junagadh, Gujarat, India
- 5Cleveland Clinic Florida, Weston, FL, USA
- 6Internal Medicine Residency, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, FL, USA
- 7Department of Medicine, SBKS Medical College and Research Center, Vadodara, Gujarat, India
- 8Family Medicine Residency, St Joseph’s Hospital, Bethpage, NY, USA
- 9Department of Neurology, Prisma Health/University of South Carolina, Columbia, SC, USA
- 10Department of Neurology, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL, USA
- 11Department of Biomedical Engineering, Florida Atlantic University, Boca Raton, FL, USA
- 12Department of Technology and Clinical Trials, Advanced Research LLC, Deerfield Beach, FL, USA
- 13Department of Information Technology and Operations Management (ITOM), College of Business, Florida Atlantic University, Boca Raton, FL, USA
Related
- Multicenter Retrospective Study of LCIG Therapy in Japan: Efficacy, Factors Associated with Discontinuation, and Case-based Insights
- Parasympathetic dysfunction assessed by deep-breathing CVR-R is associated with early discontinuation of oral semaglutide in type 2 diabetes: A multicenter retrospective study.
- CSF pharmacokinetics-pharmacodynamics of linezolid in critically brain injured patients, with or without central nervous system healthcare-associated infection. The PK-Pop-LCR Study: A Multicentre Pharmacokinetics and Pharmacodynamics Population Study
- Clinical Course and Discontinuation of Olanzapine Long-Acting Injectable: A Retrospective Case Series Including a Case of Post-Injection Delirium/Sedation Syndrome
- Changes in Tacrolimus and Everolimus Trough Concentrations and Dose Requirements After Initiation and Discontinuation of Letermovir Prophylaxis in Kidney Transplant Recipients: A Single-Center Retrospective Study
BibTeX
@article{kachhadia2026cytochrome,
title = {{Cytochrome P450 2D6 Metabolizer Phenotype Is Associated With Metoprolol Pharmacodynamics But Not With Metoprolol Discontinuation: A Retrospective Cohort Study in the All of Us Research Program}},
author = {Meet Popatbhai Kachhadia and Piyush Puri and Nachiketa Buha and Jay Vadodariya and Shashi Kant and Harrison Giknavorian and Amrit Gautam and Jimik Patel and Lakshya Kumar and Juber D. Shaikh and Gurnoor Gill and Deep Prajapati and Quacian Dennis and Harshal A. Sanghvi},
journal = {Journal of Clinical Medicine Research},
year = {2026},
month = sep,
url = {https://europepmc.org/article/PMC/PMC13661095},
note = {CC BY},
}
RIS
TY - JOUR
TI - Cytochrome P450 2D6 Metabolizer Phenotype Is Associated With Metoprolol Pharmacodynamics But Not With Metoprolol Discontinuation: A Retrospective Cohort Study in the All of Us Research Program
AU - Meet Popatbhai Kachhadia
AU - Piyush Puri
AU - Nachiketa Buha
AU - Jay Vadodariya
AU - Shashi Kant
AU - Harrison Giknavorian
AU - Amrit Gautam
AU - Jimik Patel
AU - Lakshya Kumar
AU - Juber D. Shaikh
AU - Gurnoor Gill
AU - Deep Prajapati
AU - Quacian Dennis
AU - Harshal A. Sanghvi
PY - 2026
DA - 2026/09/01
JO - Journal of Clinical Medicine Research
UR - https://europepmc.org/article/PMC/PMC13661095
SN - 1918-3003
ER -