Peer-reviewedCC BYFrontiers in immunology
SPHK1 drives pyroptosis via ROS-dependent activation of the NLRP3 inflammasome in non-infectious uveitis
4 affiliations
- 1Ophthalmology Medical Center, Chongqing Key Laboratory for the Prevention and Treatment of Major Blinding Eye Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing Branch (Municipality Division) of National Clinical Research Centre for Ocular Diseases , ,
- 2Ophthalmology Medical Center, The Second Affiliated Hospital of Wannan Medical College , , ,
- 3Ophthalmology Medical Center, Beijing Shijitan Hospital Affiliated to Capital Medical University , ,
- 4Wannan Medical College , , ,
Related
- Hydroxytyrosol Restrains NLRP3 Inflammasome Activation and Pyroptosis Through the TLR4/NF-κB Pathway to Prevent Mycoplasma gallisepticum-Inflammation
- Macrophages in non-infectious uveitis: cell origin, disease stage, evidence provenance, and therapeutic maturity
- 6:2 Cl-PFESA induces sex-dependent lung inflammation through NLRP12 inflammasome activation and pulmonary microbiota dysbiosis
- Single-cell sequencing of non-infectious and viral uveitis defines distinct mechanisms in ocular inflammation
- Genetic susceptibility and clinical validation of ICAM-5 in immune-mediated non-infectious uveitis
BibTeX
@article{hu2026sphk1,
title = {{SPHK1 drives pyroptosis via ROS-dependent activation of the NLRP3 inflammasome in non-infectious uveitis}},
author = {Lili Hu and Shaoxin Pan and Jing Wang and Suyin Mei and Haoning Pan and Rui Chang},
journal = {Frontiers in immunology},
year = {2026},
month = oct,
url = {https://europepmc.org/article/PMC/PMC13657954},
note = {CC BY},
}
RIS
TY - JOUR
TI - SPHK1 drives pyroptosis via ROS-dependent activation of the NLRP3 inflammasome in non-infectious uveitis
AU - Lili Hu
AU - Shaoxin Pan
AU - Jing Wang
AU - Suyin Mei
AU - Haoning Pan
AU - Rui Chang
PY - 2026
DA - 2026/10/16
JO - Frontiers in immunology
UR - https://europepmc.org/article/PMC/PMC13657954
SN - 1664-3224
ER -