Vitamin D status and its association with musculoskeletal symptoms and degenerative bone disease among orthopaedic outpatients in Nepal
- 1Central Department of Statistics, Tribhuvan University, Mahendra Multiple Campus
- 2Department of Orthopaedics, Rapti Academy of Health Sciences
- 3Department of Statistics, Tribhuvan University, Tri Chandra College
Abstract
The objective of this study was to evaluate the association between vitamin D status and demographic characteristics, musculoskeletal pain, and degenerative bone diseases in Orthopedic outpatients. A cross-sectional study was conducted among 215 patients attending the Orthopaedic Outpatient Department of a hospital in Nepal. Data were collected using a structured questionnaire, and serum vitamin D levels were categorized as deficient (≤ 20 ng/mL), insufficient (21–29 ng/mL), and sufficient (≥ 30 ng/mL). Multiple correspondence analysis (MCA) and ordinal logistic regression analysis were used to examine the distribution and correlates of vitamin D status. The most prevalent category was vitamin D insufficiency (21–29 ng/mL), with 62.3% of participants affected, and 9.8% were vitamin D deficient. Females were less likely to be in the higher vitamin D category than males (AOR = 0.37, 95% CI: 0.18–0.77, p = 0.008), and participants without degenerative bone disease had lower odds of being in a higher vitamin D category (AOR = 0.40, 95% CI: 0.20–0.81, p = 0.010). MCA showed that Body pain was a common symptom among participants with suboptimal vitamin D status. Further longitudinal, multicenter studies are needed to elucidate the association between vitamin D status and degenerative bone disease and symptoms.
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BibTeX
@article{paudel2026vitamin,
title = {{Vitamin D status and its association with musculoskeletal symptoms and degenerative bone disease among orthopaedic outpatients in Nepal}},
author = {Prabha Paudel and Bikash Neupane and Nischal Sharma and Pramila Paudel},
journal = {Scientific Reports},
year = {2026},
month = sep,
doi = {10.1038/s41598-026-71469-3},
url = {https://doi.org/10.1038/s41598-026-71469-3},
note = {CC BY},
}
RIS
TY - JOUR
TI - Vitamin D status and its association with musculoskeletal symptoms and degenerative bone disease among orthopaedic outpatients in Nepal
AU - Prabha Paudel
AU - Bikash Neupane
AU - Nischal Sharma
AU - Pramila Paudel
PY - 2026
DA - 2026/09/01
JO - Scientific Reports
DO - 10.1038/s41598-026-71469-3
UR - https://doi.org/10.1038/s41598-026-71469-3
AB - The objective of this study was to evaluate the association between vitamin D status and demographic characteristics, musculoskeletal pain, and degenerative bone diseases in Orthopedic outpatients. A cross-sectional study was conducted among 215 patients attending the Orthopaedic Outpatient Department of a hospital in Nepal. Data were collected using a structured questionnaire, and serum vitamin D levels were categorized as deficient (≤ 20 ng/mL), insufficient (21–29 ng/mL), and sufficient (≥ 30 ng/mL). Multiple correspondence analysis (MCA) and ordinal logistic regression analysis were used to examine the distribution and correlates of vitamin D status. The most prevalent category was vitamin D insufficiency (21–29 ng/mL), with 62.3% of participants affected, and 9.8% were vitamin D deficient. Females were less likely to be in the higher vitamin D category than males (AOR = 0.37, 95% CI: 0.18–0.77, p = 0.008), and participants without degenerative bone disease had lower odds of being in a higher vitamin D category (AOR = 0.40, 95% CI: 0.20–0.81, p = 0.010). MCA showed that Body pain was a common symptom among participants with suboptimal vitamin D status. Further longitudinal, multicenter studies are needed to elucidate the association between vitamin D status and degenerative bone disease and symptoms.
SN - 2045-2322
ER -