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Peer-reviewedCC BY-NC-NDNeurology(R) neuroimmunology & neuroinflammation

A 35-Year-Old Woman With Multiple Sclerosis and a New Atypical Thalamic Lesion: A Case Report From the National Multiple Sclerosis Society Case Conference Proceedings.

8 affiliations
  1. 1Neurology, Beth Israel Deaconess Medical Center, Boston, MA.
  2. 2Neuro-oncology, Massachusetts General Hospital, Boston.
  3. 3Neuro-oncology, UT Southwestern Medical Center, Dallas, TX.
  4. 4Pathology, Massachusetts General Hospital, Boston.
  5. 5Neurology, Columbia University, New York, NY.
  6. 6Neurology, UCSF Health, San Francisco, CA.
  7. 7Virginia Commonwealth University, Richmond; and.
  8. 8Neurology, Massachusetts General Hospital, Boston.

Abstract

In multiple sclerosis (MS), new or enlarging brain lesions often suggest disease activity, but infections or tumors may mimic relapse. We report a 35-year-old woman with MS whose enlarging thalamic lesion was ultimately diagnosed as diffuse midline glioma, underscoring the need for prompt evaluation of atypical MRI findings.

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BibTeX
@article{michaelson202635yearold,
  title = {{A 35-Year-Old Woman With Multiple Sclerosis and a New Atypical Thalamic Lesion: A Case Report From the National Multiple Sclerosis Society Case Conference Proceedings.}},
  author = {Nara Miriam Michaelson and Isabel C Arrillaga-Romany and Justin T Jordan and Maria Martinez-Lage and Claire Riley and Scott S Zamvil and Myla D Goldman and Eric C Klawiter},
  journal = {Neurology(R) neuroimmunology \& neuroinflammation},
  year = {2026},
  month = oct,
  doi = {10.1212/nxi.0000000000200667},
  url = {https://europepmc.org/article/MED/42879709},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - A 35-Year-Old Woman With Multiple Sclerosis and a New Atypical Thalamic Lesion: A Case Report From the National Multiple Sclerosis Society Case Conference Proceedings.
AU  - Nara Miriam Michaelson
AU  - Isabel C Arrillaga-Romany
AU  - Justin T Jordan
AU  - Maria Martinez-Lage
AU  - Claire Riley
AU  - Scott S Zamvil
AU  - Myla D Goldman
AU  - Eric C Klawiter
PY  - 2026
DA  - 2026/10/14
JO  - Neurology(R) neuroimmunology & neuroinflammation
DO  - 10.1212/nxi.0000000000200667
UR  - https://europepmc.org/article/MED/42879709
AB  - In multiple sclerosis (MS), new or enlarging brain lesions often suggest disease activity, but infections or tumors may mimic relapse. We report a 35-year-old woman with MS whose enlarging thalamic lesion was ultimately diagnosed as diffuse midline glioma, underscoring the need for prompt evaluation of atypical MRI findings.
SN  - 2332-7812
ER  -