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Peer-reviewedCC BY-NCDermatology practical & conceptual

Evaluation of Fibromyalgia Frequency in Chronic Spontaneous Urticaria Patients Referred to a Tertiary Dermatology Outpatient Clinic.

  • Fatma Etgü1
  • Derya Çırakoğlu2
  1. 1Department of Dermatology, Faculty of Medicine, Ordu University, Ordu, Turkey.
  2. 2Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Ordu University, Ordu, Turkey.
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Abstract

Introduction

Chronic spontaneous urticaria (CSU) and fibromyalgia (FM) share overlapping features such as autoimmunity, psychological influence, and female predominance. Previous studies show conflicting results on FM prevalence in CSU patients.Objectives

This study aimed to assess the prevalence of concurrent FM in patients with CSU.Methods

A cross-sectional study including 257 CSU patients and age- and sex-matched healthy controls. Data collected included demographics, disease duration, severity (UAS-7), and quality of life (DLQI). FM was diagnosed using the 2016 ACR criteria.Results

The prevalence of FM was 18.98% in CSU patients and 4.43% for the control group (P<0.01). The mean WPI and SSS scores were higher in the CSU group; WPI was statistically significant (P < 0.01), whereas SSS showed no statistically significant difference (P = 0.05). CSU patients with FM had longer disease duration, higher disease severity, and more impairment in life. Furthermore, female CSU patients had more FM than did male CSU patients (P<0.001).Conclusions

FM was more prevalent among patients with CSU compared to the control group. Female sex, higher disease severity, and impaired quality of life were significantly associated with FM in CSU patients. Given the reduced quality of life observed in individuals with both conditions, clinicians should consider evaluating CSU patients, especially those with severe symptoms, for FM to ensure accurate diagnosis and comprehensive management. Further studies are needed to clarify the nature of this association.

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Cite

BibTeXRIS
BibTeX
@article{etgu2026evaluation,
  title = {{Evaluation of Fibromyalgia Frequency in Chronic Spontaneous Urticaria Patients Referred to a Tertiary Dermatology Outpatient Clinic.}},
  author = {Fatma Etgü and Derya Çırakoğlu},
  journal = {Dermatology practical \& conceptual},
  year = {2026},
  month = jul,
  doi = {10.5826/dpc.1603a6659},
  url = {https://europepmc.org/article/MED/42858419},
  note = {CC BY-NC},
}
RIS
TY  - JOUR
TI  - Evaluation of Fibromyalgia Frequency in Chronic Spontaneous Urticaria Patients Referred to a Tertiary Dermatology Outpatient Clinic.
AU  - Fatma Etgü
AU  - Derya Çırakoğlu
PY  - 2026
DA  - 2026/07/31
JO  - Dermatology practical & conceptual
DO  - 10.5826/dpc.1603a6659
UR  - https://europepmc.org/article/MED/42858419
AB  - Introduction  Chronic spontaneous urticaria (CSU) and fibromyalgia (FM) share overlapping features such as autoimmunity, psychological influence, and female predominance. Previous studies show conflicting results on FM prevalence in CSU patients.Objectives  This study aimed to assess the prevalence of concurrent FM in patients with CSU.Methods  A cross-sectional study including 257 CSU patients and age- and sex-matched healthy controls. Data collected included demographics, disease duration, severity (UAS-7), and quality of life (DLQI). FM was diagnosed using the 2016 ACR criteria.Results  The prevalence of FM was 18.98% in CSU patients and 4.43% for the control group (P<0.01). The mean WPI and SSS scores were higher in the CSU group; WPI was statistically significant (P < 0.01), whereas SSS showed no statistically significant difference (P = 0.05). CSU patients with FM had longer disease duration, higher disease severity, and more impairment in life. Furthermore, female CSU patients had more FM than did male CSU patients (P<0.001).Conclusions  FM was more prevalent among patients with CSU compared to the control group. Female sex, higher disease severity, and impaired quality of life were significantly associated with FM in CSU patients. Given the reduced quality of life observed in individuals with both conditions, clinicians should consider evaluating CSU patients, especially those with severe symptoms, for FM to ensure accurate diagnosis and comprehensive management. Further studies are needed to clarify the nature of this association.
SN  - 2160-9381
ER  -