Anaesthesia management of a giant retroperitoneal liposarcoma: a case report and literature review.
- 1Department of Anesthesiology, Peking University People 's Hospital, Beijing, China.
- 2Department of Retroperitoneal Oncology, National Center for Trauma Medicine, Peking University People's Hospital, Beijing, China.
Abstract
Soft tissue sarcomas account for less than 1% of all malignant tumors, of which 10∼15% are located in the retroperitoneum, and liposarcoma constitutes 20% of all soft tissue sarcomas. Of note, retroperitoneal liposarcoma is a rare malignant tumor, with recurrence and asymptomatic characteristics at the initial stage until the liposarcoma is large enough to compress abdominal organs. Those larger than 20 kg, known as "giant liposarcomas," are extremely rare. Most retroperitoneal liposarcoma represents expansive growth, and lymph node metastasis or distant metastasis is rarely reported, making surgical resection as the most effective treatment. Because giant retroperitoneal liposarcomas can cause substantial compression of abdominal and retroperitoneal structures, perioperative management may be complicated by impaired venous return, respiratory compromise, hemodynamic instability, difficult tumor dissection, and major blood loss. Current consensus emphasizes management of primary retroperitoneal sarcoma in experienced multidisciplinary centers. In addition, recent perioperative literature highlights the importance of individualized preoperative optimization, invasive hemodynamic monitoring, goal-directed fluid therapy, adequate blood-product preparation, and structured postoperative care. In this context, we reported a case of a giant retroperitoneal liposarcoma with a diameter 52 cm× 38 cm×30 cm and a weight of 31 kg. Through multidisciplinary team (MDT) consultation, the tumor compressing the surrounding organs was successfully removed.
Related
- Case Report: Recurrent retroperitoneal dedifferentiated liposarcoma after surgery
- Real-World Management and Survival Outcomes in Patients with Primary or Recurrent Retroperitoneal Liposarcoma: A Single-Center Retrospective Cohort Study
- Case Report: Giant congenital hydronephrosis presenting as massive retroperitoneal cystic lesion with literature review
- Computed tomography findings of a retroperitoneal chronic expanding hematoma with multiple hemangiomas: A case report and literature review
- Giant primary retroperitoneal myxofibrosarcoma mimicking myxoid liposarcoma: a diagnostic and surgical challenge
BibTeX
@article{huo2026anaesthesia,
title = {{Anaesthesia management of a giant retroperitoneal liposarcoma: a case report and literature review.}},
author = {Fei Huo and Bin An and Hansheng Liang and Liang Sun and Mengmeng Xiao and Chenghua Luo and Yi Feng},
journal = {Frontiers in surgery},
year = {2026},
month = oct,
doi = {10.3389/fsurg.2026.1901393},
url = {https://europepmc.org/article/MED/42923201},
note = {CC BY},
}
RIS
TY - JOUR
TI - Anaesthesia management of a giant retroperitoneal liposarcoma: a case report and literature review.
AU - Fei Huo
AU - Bin An
AU - Hansheng Liang
AU - Liang Sun
AU - Mengmeng Xiao
AU - Chenghua Luo
AU - Yi Feng
PY - 2026
DA - 2026/10/08
JO - Frontiers in surgery
DO - 10.3389/fsurg.2026.1901393
UR - https://europepmc.org/article/MED/42923201
AB - Soft tissue sarcomas account for less than 1% of all malignant tumors, of which 10∼15% are located in the retroperitoneum, and liposarcoma constitutes 20% of all soft tissue sarcomas. Of note, retroperitoneal liposarcoma is a rare malignant tumor, with recurrence and asymptomatic characteristics at the initial stage until the liposarcoma is large enough to compress abdominal organs. Those larger than 20 kg, known as "giant liposarcomas," are extremely rare. Most retroperitoneal liposarcoma represents expansive growth, and lymph node metastasis or distant metastasis is rarely reported, making surgical resection as the most effective treatment. Because giant retroperitoneal liposarcomas can cause substantial compression of abdominal and retroperitoneal structures, perioperative management may be complicated by impaired venous return, respiratory compromise, hemodynamic instability, difficult tumor dissection, and major blood loss. Current consensus emphasizes management of primary retroperitoneal sarcoma in experienced multidisciplinary centers. In addition, recent perioperative literature highlights the importance of individualized preoperative optimization, invasive hemodynamic monitoring, goal-directed fluid therapy, adequate blood-product preparation, and structured postoperative care. In this context, we reported a case of a giant retroperitoneal liposarcoma with a diameter 52 cm× 38 cm×30 cm and a weight of 31 kg. Through multidisciplinary team (MDT) consultation, the tumor compressing the surrounding organs was successfully removed.
SN - 2296-875X
ER -