Research attitudes mediate the association between educational attainment and willingness to participate in Alzheimer's disease research beyond Alzheimer's disease knowledge
- 1Department of Psychology, The Ohio State University
Abstract
STRUCTURED ABSTRACTO_ST_ABSINTRODUCTIONC_ST_ABSThis study examined the extent to which educational attainment, Alzheimers disease (AD) knowledge, and research attitudes are associated with willingness to participate in AD research, and whether AD knowledge and research attitudes mediate associations between educational attainment and willingness to participate.
METHODS201 older adults completed self-report measures of AD knowledge, research attitudes, prior research participation, and willingness to participate in diagnostic procedures (neuropsychological assessment, blood draw, brain MRI) and non-pharmacological intervention research (tracking physical activity, aerobic exercise).
RESULTSFavorable research attitudes were consistently associated with greater willingness to participate across all proposed research activities, and research attitudes mediated the relationship between educational attainment and willingness to participate in research. In contrast, AD knowledge did not mediate the association between educational attainment and willingness to participate.
DISCUSSIONResearch attitudes may be a key, modifiable determinant of willingness to participate in AD research and a promising focus for broadening AD research participation.
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BibTeX
@misc{bonta2026research,
title = {{Research attitudes mediate the association between educational attainment and willingness to participate in Alzheimer's disease research beyond Alzheimer's disease knowledge}},
author = {K. M. Bonta and E. Corbett and M. K. Alemu and B. D. Darge and L. K. HIlderbrand and K. A. Richardson and S. S. Ogonuwe and I. M. Blum and K. Shen and M. K. McGuire and D. H. Pandhi and L. W. Gallagher and J. M. Hunter and F. Grant and W. Simmons and L. Davis and P. Shields and S. Cooper and M. Rouse and K. S. Wilson-Lawson and C. Hughes-Culp and M. Howard and M. Monroe and M. Coleman and D. Leath and J. Butsch and N. Davis and J. Henry and P. Gregory and J. G. Grant},
howpublished = {medRxiv},
year = {2026},
month = oct,
doi = {10.64898/2026.10.13.26365095},
url = {https://www.medrxiv.org/content/10.64898/2026.10.13.26365095v1},
note = {CC BY-NC-ND},
}
RIS
TY - UNPB
TI - Research attitudes mediate the association between educational attainment and willingness to participate in Alzheimer's disease research beyond Alzheimer's disease knowledge
AU - K. M. Bonta
AU - E. Corbett
AU - M. K. Alemu
AU - B. D. Darge
AU - L. K. HIlderbrand
AU - K. A. Richardson
AU - S. S. Ogonuwe
AU - I. M. Blum
AU - K. Shen
AU - M. K. McGuire
AU - D. H. Pandhi
AU - L. W. Gallagher
AU - J. M. Hunter
AU - F. Grant
AU - W. Simmons
AU - L. Davis
AU - P. Shields
AU - S. Cooper
AU - M. Rouse
AU - K. S. Wilson-Lawson
AU - C. Hughes-Culp
AU - M. Howard
AU - M. Monroe
AU - M. Coleman
AU - D. Leath
AU - J. Butsch
AU - N. Davis
AU - J. Henry
AU - P. Gregory
AU - J. G. Grant
PY - 2026
DA - 2026/10/13
PB - medRxiv
DO - 10.64898/2026.10.13.26365095
UR - https://www.medrxiv.org/content/10.64898/2026.10.13.26365095v1
AB - STRUCTURED ABSTRACTO_ST_ABSINTRODUCTIONC_ST_ABSThis study examined the extent to which educational attainment, Alzheimers disease (AD) knowledge, and research attitudes are associated with willingness to participate in AD research, and whether AD knowledge and research attitudes mediate associations between educational attainment and willingness to participate. METHODS201 older adults completed self-report measures of AD knowledge, research attitudes, prior research participation, and willingness to participate in diagnostic procedures (neuropsychological assessment, blood draw, brain MRI) and non-pharmacological intervention research (tracking physical activity, aerobic exercise). RESULTSFavorable research attitudes were consistently associated with greater willingness to participate across all proposed research activities, and research attitudes mediated the relationship between educational attainment and willingness to participate in research. In contrast, AD knowledge did not mediate the association between educational attainment and willingness to participate. DISCUSSIONResearch attitudes may be a key, modifiable determinant of willingness to participate in AD research and a promising focus for broadening AD research participation.
ER -