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Peer-reviewedCC BY 4.0International Journal of Molecular Sciences

Molecular Mechanisms and Network Integration of Oxylipin Signaling in Plant Abiotic Stress Tolerance

  • Guljakhon Eshbekova1,2
  • Anh Duc Tran1
  • Kyoungwon Cho1
  • Manh An Vu1
  • Jeong-Il Kim1
  • Hanh Thi Thuy Nguyen3
  • Oksoo Han1,4
4 affiliations
  1. 1Graduate School and Kumho Life Science Laboratory, Department of Integrative Food, Bioscience and Biotechnology, College of Agriculture and Life Sciences, Chonnam National University, Gwangju 61186, Republic of Korea
  2. 2Molecular Biotechnology and Modern Botanical Research Laboratory, Department of Biotechnology and Plant Genomics, Samarkand State University named after Sharof Rashidov, University Boulevard 15, Samarkand 140100, Uzbekistan
  3. 3Faculty of Biotechnology, Vietnam National University of Agriculture, Hanoi 12406, Vietnam
  4. 4Department of Molecular Biotechnology, Chonnam National University, Gwangju 61186, Republic of Korea
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Abstract

Plant oxylipins are a diverse group of oxygenated fatty acid derivatives that function as important signaling molecules in plant responses to abiotic stress. Although jasmonates, particularly jasmonic acid (JA) and its derivatives, have been extensively studied, increasing evidence demonstrates that other oxylipin classes, including 12-oxophytodienoic acid (OPDA), green leaf volatiles (GLVs), reactive electrophilic oxylipins (RES), and peroxygenase (PXG)-derived oxylipins, also contribute to stress adaptation. This review summarizes current understanding of the molecular mechanisms underlying oxylipin signal perception, transduction, and regulation, with particular emphasis on interactions with other plant hormone pathways, reactive oxygen species (ROS), Calcium (Ca2+), and mitogen-activated protein kinase (MAPK) signaling. We further examine transcriptional, post-transcriptional, and post-translational mechanisms that regulate oxylipin responses and discuss their integration across individual and combined abiotic stresses. Particular attention is given to experimentally established mechanisms while distinguishing emerging or unresolved signaling processes. Understanding these interconnected signaling mechanisms will be important for developing strategies to improve crop resilience under global climate change.

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Cite

BibTeXRIS
BibTeX
@article{eshbekova2026molecular,
  title = {{Molecular Mechanisms and Network Integration of Oxylipin Signaling in Plant Abiotic Stress Tolerance}},
  author = {Guljakhon Eshbekova and Anh Duc Tran and Kyoungwon Cho and Manh An Vu and Jeong-Il Kim and Hanh Thi Thuy Nguyen and Oksoo Han},
  journal = {International Journal of Molecular Sciences},
  year = {2026},
  month = sep,
  doi = {10.3390/ijms27188362},
  url = {https://www.mdpi.com/1422-0067/27/18/8362},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Molecular Mechanisms and Network Integration of Oxylipin Signaling in Plant Abiotic Stress Tolerance
AU  - Guljakhon Eshbekova
AU  - Anh Duc Tran
AU  - Kyoungwon Cho
AU  - Manh An Vu
AU  - Jeong-Il Kim
AU  - Hanh Thi Thuy Nguyen
AU  - Oksoo Han
PY  - 2026
DA  - 2026/09/19
JO  - International Journal of Molecular Sciences
DO  - 10.3390/ijms27188362
UR  - https://www.mdpi.com/1422-0067/27/18/8362
AB  - Plant oxylipins are a diverse group of oxygenated fatty acid derivatives that function as important signaling molecules in plant responses to abiotic stress. Although jasmonates, particularly jasmonic acid (JA) and its derivatives, have been extensively studied, increasing evidence demonstrates that other oxylipin classes, including 12-oxophytodienoic acid (OPDA), green leaf volatiles (GLVs), reactive electrophilic oxylipins (RES), and peroxygenase (PXG)-derived oxylipins, also contribute to stress adaptation. This review summarizes current understanding of the molecular mechanisms underlying oxylipin signal perception, transduction, and regulation, with particular emphasis on interactions with other plant hormone pathways, reactive oxygen species (ROS), Calcium (Ca2+), and mitogen-activated protein kinase (MAPK) signaling. We further examine transcriptional, post-transcriptional, and post-translational mechanisms that regulate oxylipin responses and discuss their integration across individual and combined abiotic stresses. Particular attention is given to experimentally established mechanisms while distinguishing emerging or unresolved signaling processes. Understanding these interconnected signaling mechanisms will be important for developing strategies to improve crop resilience under global climate change.
SN  - 1422-0067
ER  -