Skip to content
DraconiticResearch
Search Sources API
197,783 studies31 sourcesUpdated 9 min ago
Peer-reviewedLicence not statedAutophagy

E-cigarette aerosols induce the hydrolysis of lysosomal glycerophospholipids through PLA2G4A activation initiated by nicotine binding to CHRNA3/α3 nAChR in airway epithelial cells

5 affiliations
  1. 1Key Lab of Environmental Medicine Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, China
  2. 2Key Lab of Modern Toxicology of Ministry of Education, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China
  3. 3State Key Lab of Reproductive Medicine and Offspring Health, Institute of Toxicology, Nanjing Medical University, Nanjing, China
  4. 4Department of Cadre Respiratory, The Affiliated Jinling Hospital of Nanjing Medical University, Nanjing, China
  5. 5Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

Related

  1. Mixture-Dependent Toxicity of E-Cigarette Constituents: Cytotoxicity, Inflammation, and DNA-Repair-Associated Protein Responses in Bronchial Epithelial Cells.
    Ehsanul Kabir, Joshua Furst, Thivanka Muthumalage
    ToxicsPeer-reviewedCC BYFull textOncologyEurope PMC
  2. 4-Octyl itaconate ameliorates cigarette smoke-induced chronic obstructive pulmonary disease by suppressing necroptosis in alveolar macrophages via Nrf2 activation
    Zhe Wang, Xiaofeng Li, Tingting Zhang +4
    Scientific ReportsPeer-reviewedCC BYFull text1 citedGeneral medicineDOAJ
  3. Chronic TFE3 activation in TFE3-associated neurodevelopmental disorder drives metabolic rigidity, lysosomal failure, and cell-extracellular matrix destabilization
    José A. Martina, Akriti Prashar, Ana M. Pasapera +3
    Nature CommunicationsPeer-reviewedCC BY 4.0Full textEpidemiology & public healthCrossref
  4. Monocyte-macrophage sensing of calciprotein particles in CKD-associated vascular calcification: lysosomal stress and inflammasome activation
    Zhiqiang Xu, Yuying Jiang, Kangwei Wang +1
    Frontiers in ImmunologyPeer-reviewedCC BY 4.0Full textImmunologyGeneral medicineCrossrefDOAJ
  5. Targeted lysosomal activation in bladder epithelium enhances clearance of intracellular uropathogenic Escherichia coli
    Kathrin Tomasek, Kristina Skurvydaite, Gauri Paduthol +6
    PLOS PathogensPeer-reviewedCC BY 4.0Full text1 citedCell biologyPhysiologyPLOS
BibTeX
@article{yu2026ecigarette,
  title = {{E-cigarette aerosols induce the hydrolysis of lysosomal glycerophospholipids through PLA2G4A activation initiated by nicotine binding to CHRNA3/α3 nAChR in airway epithelial cells}},
  author = {Yongquan Yu and Shuyu Xu and Liu Yang and Shuge Shu and Haojie Zhou and Zhencheng Hua and Li Wang and Yingran Zhu and Aiming Shi and Rong Xia and Chao Chen and Shou-Lin Wang},
  journal = {Autophagy},
  year = {2026},
  month = jun,
  doi = {10.1080/15548627.2026.2689038},
  url = {https://doi.org/10.1080/15548627.2026.2689038},
}
RIS
TY  - JOUR
TI  - E-cigarette aerosols induce the hydrolysis of lysosomal glycerophospholipids through PLA2G4A activation initiated by nicotine binding to CHRNA3/α3 nAChR in airway epithelial cells
AU  - Yongquan Yu
AU  - Shuyu Xu
AU  - Liu Yang
AU  - Shuge Shu
AU  - Haojie Zhou
AU  - Zhencheng Hua
AU  - Li Wang
AU  - Yingran Zhu
AU  - Aiming Shi
AU  - Rong Xia
AU  - Chao Chen
AU  - Shou-Lin Wang
PY  - 2026
DA  - 2026/06/21
JO  - Autophagy
DO  - 10.1080/15548627.2026.2689038
UR  - https://doi.org/10.1080/15548627.2026.2689038
SN  - 1554-8627
SN  - 1554-8635
ER  -