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Peer-reviewedCC BY 4.0BMC Public Health

Habitual sodium intake and metabolic abnormalities in Korean adults with obesity: a cross-sectional analysis of a prospective cohort

  • Soo-Hyun Park1
  • Minyoung Lee2,3
  • Hee-Joo Kang1
  • Jin-Hee Kim1
  • Jin-Taek Hwang1
  • Jina Chung4
  • Hyojee Joung5,6
  • Sungha Park7,8
  • Jae-Ho Park1
8 affiliations
  1. 1Division of Food Functionality Research, Korea Food Research Institute, Wanju, Republic of Korea
  2. 2Department of Internal Medicine, Division of Endocrinology and Metabolism, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
  3. 3Institute of Endocrine Research, Yonsei University College of Medicine, Seoul, Republic of Korea
  4. 4Department of Biomedical Science, Seoul National University Graduate School, Seoul, Republic of Korea
  5. 5Department of Public Health, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea
  6. 6Institute of Health and Environment, Seoul National University, Seoul, Republic of Korea
  7. 7Department of Internal Medicine, Division of Cardiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
  8. 8Integrative Research Center for Cerebrovascular and Cardiovascular Diseases, Yonsei University College of Medicine, Seoul, Republic of Korea
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Abstract

Background: Sodium intake is well recognized for its contribution to hypertension, but growing evidence suggests broader metabolic effects, particularly among individuals with obesity who are vulnerable to metabolic disturbances. This study investigated the cross-sectional associations between habitual sodium intake and metabolic diseases and related markers using baseline data from a prospective cohort of Korean adults with obesity.

Methods: Participants with obesity (BMI ≥ 25 kg/m2) and at least one metabolic condition were recruited from Severance Hospital, Seoul, Republic of Korea. Sodium intake was assessed using a food frequency questionnaire, and associations with diabetes, dyslipidemia, hypertension, and cardiovascular disease were evaluated using multivariable regression models. Mean differences in metabolic markers across sodium tertiles were examined using analysis of covariance with sex stratification.

Results: Of the 633 individuals enrolled, 487 with obesity were included in the final analysis after excluding non-obese participants and those with implausible energy intake. No statistically significant associations were observed between sodium intake and the prevalence of type 2 diabetes, dyslipidemia, hypertension, or cardiovascular disease. In sex-stratified biomarker analyses, LDL-C, non-HDL-C, CRI-I, and CRI-II differed across sodium tertiles among women, whereas no such differences were observed in men.

Conclusions: In Korean adults with obesity and pre-existing metabolic conditions, increasing sodium intake was not significantly associated with higher prevalence of major metabolic diseases. In exploratory sex-stratified analyses, several atherogenic lipid markers differed across sodium intake tertiles among women only. This within-women pattern should be regarded as hypothesis-generating and requires confirmation in future longitudinal analyses of this cohort.

Supplementary Information: The online version contains supplementary material available at https://doi.org/10.1186/s12889-026-28903-y.

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Cite

BibTeXRIS
BibTeX
@article{park2026habitual,
  title = {{Habitual sodium intake and metabolic abnormalities in Korean adults with obesity: a cross-sectional analysis of a prospective cohort}},
  author = {Soo-Hyun Park and Minyoung Lee and Hee-Joo Kang and Jin-Hee Kim and Jin-Taek Hwang and Jina Chung and Hyojee Joung and Sungha Park and Jae-Ho Park},
  journal = {BMC Public Health},
  year = {2026},
  month = aug,
  doi = {10.1186/s12889-026-28903-y},
  url = {https://doi.org/10.1186/s12889-026-28903-y},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Habitual sodium intake and metabolic abnormalities in Korean adults with obesity: a cross-sectional analysis of a prospective cohort
AU  - Soo-Hyun Park
AU  - Minyoung Lee
AU  - Hee-Joo Kang
AU  - Jin-Hee Kim
AU  - Jin-Taek Hwang
AU  - Jina Chung
AU  - Hyojee Joung
AU  - Sungha Park
AU  - Jae-Ho Park
PY  - 2026
DA  - 2026/08/06
JO  - BMC Public Health
DO  - 10.1186/s12889-026-28903-y
UR  - https://doi.org/10.1186/s12889-026-28903-y
AB  - Background: Sodium intake is well recognized for its contribution to hypertension, but growing evidence suggests broader metabolic effects, particularly among individuals with obesity who are vulnerable to metabolic disturbances. This study investigated the cross-sectional associations between habitual sodium intake and metabolic diseases and related markers using baseline data from a prospective cohort of Korean adults with obesity.  Methods: Participants with obesity (BMI ≥ 25 kg/m2) and at least one metabolic condition were recruited from Severance Hospital, Seoul, Republic of Korea. Sodium intake was assessed using a food frequency questionnaire, and associations with diabetes, dyslipidemia, hypertension, and cardiovascular disease were evaluated using multivariable regression models. Mean differences in metabolic markers across sodium tertiles were examined using analysis of covariance with sex stratification.  Results: Of the 633 individuals enrolled, 487 with obesity were included in the final analysis after excluding non-obese participants and those with implausible energy intake. No statistically significant associations were observed between sodium intake and the prevalence of type 2 diabetes, dyslipidemia, hypertension, or cardiovascular disease. In sex-stratified biomarker analyses, LDL-C, non-HDL-C, CRI-I, and CRI-II differed across sodium tertiles among women, whereas no such differences were observed in men.  Conclusions: In Korean adults with obesity and pre-existing metabolic conditions, increasing sodium intake was not significantly associated with higher prevalence of major metabolic diseases. In exploratory sex-stratified analyses, several atherogenic lipid markers differed across sodium intake tertiles among women only. This within-women pattern should be regarded as hypothesis-generating and requires confirmation in future longitudinal analyses of this cohort.  Supplementary Information: The online version contains supplementary material available at https://doi.org/10.1186/s12889-026-28903-y.
SN  - 1471-2458
ER  -