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Peer-reviewedCC BY 4.0RSC Chemical Biology

Bioorthogonal, twice-clickable fluorogenic probes for two-photon live-cell microscopy

  • Malo Gourvest1,2,3
  • Emilie Plantiveau4
  • Aurélie Rodriguez1,2,3
  • Emma de Bastiani4
  • Delphine Naud-Martin1,2,3
  • Frédéric Bolze5
  • Gilles Clavier6
  • Kévin Renault1,2,3
  • Frédéric Taran4
  • Florence Mahuteau-Betzer1,2,3
6 affiliations
  1. 1CNRS UMR9187, Chemistry and Modeling for the Biology of Cancer Institut Curie, Université PSL 91400 Orsay France [email protected].
  2. 2CNRS UMR9187, Chemistry and Modeling for the Biology of Cancer, Université Paris-Saclay 91400 Orsay France.
  3. 3Inserm U1196, Actuatable Molecules for Diagnosis and Theranostics 91400 Orsay France.
  4. 4Département Médicaments et Technologies pour la Sante, SCBM, Université Paris Saclay Gif-sur-Yvette 91191 France [email protected].
  5. 5UMR7199 Faculté de Pharmacie 67401 Illkirch-Graffenstaden France.
  6. 6PPSM ENS Paris-Saclay 91190 Gif-sur-Yvette France.
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Abstract

Two-photon-excitable profluorogenic probes capable of undergoing bioorthogonal reactions in complex biological media remain exceedingly rare, despite their tremendous potential for live-cell imaging.

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Cite

BibTeXRIS
BibTeX
@article{gourvest2026bioorthogonal,
  title = {{Bioorthogonal, twice-clickable fluorogenic probes for two-photon live-cell microscopy}},
  author = {Malo Gourvest and Emilie Plantiveau and Aurélie Rodriguez and Emma de Bastiani and Delphine Naud-Martin and Frédéric Bolze and Gilles Clavier and Kévin Renault and Frédéric Taran and Florence Mahuteau-Betzer},
  journal = {RSC Chemical Biology},
  year = {2026},
  month = oct,
  doi = {10.1039/d6cb00227g},
  url = {https://hal.science/hal-05844600v1},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Bioorthogonal, twice-clickable fluorogenic probes for two-photon live-cell microscopy
AU  - Malo Gourvest
AU  - Emilie Plantiveau
AU  - Aurélie Rodriguez
AU  - Emma de Bastiani
AU  - Delphine Naud-Martin
AU  - Frédéric Bolze
AU  - Gilles Clavier
AU  - Kévin Renault
AU  - Frédéric Taran
AU  - Florence Mahuteau-Betzer
PY  - 2026
DA  - 2026/10/12
JO  - RSC Chemical Biology
DO  - 10.1039/d6cb00227g
UR  - https://hal.science/hal-05844600v1
AB  - Two-photon-excitable profluorogenic probes capable of undergoing bioorthogonal reactions in complex biological media remain exceedingly rare, despite their tremendous potential for live-cell imaging.
SN  - 2633-0679
ER  -