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Peer-reviewedCC BYCureus

When the Appendix Speaks: Colonoscopic Recognition of an Appendiceal Mucocele.

  • Caddie Nguyen1
  • Jackelyn Philip1
  • Lucas Youno1
  • Michael Herman2
  1. 1Gastroenterology, Lincoln Memorial University-DeBusk College of Osteopathic Medicine, Jacksonville, USA.
  2. 2Gastroenterology, Borland Groover, Jacksonville, USA.
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Abstract

Appendiceal mucoceles are rare, often asymptomatic lesions caused by mucin accumulation within the appendix and carry a risk of rupture leading to pseudomyxoma peritonei. We report a case of a 60-year-old man undergoing routine screening colonoscopy in whom a smooth, dome-shaped protrusion of the appendiceal orifice was incidentally identified. No biopsy was performed due to concern for underlying appendiceal pathology. Contrast-enhanced CT revealed a 2.2-cm dilated, fluid-filled appendix consistent with a mucocele. The patient underwent elective laparoscopic appendectomy, and histopathology confirmed a low-grade appendiceal mucinous neoplasm confined to the appendix with negative margins. This case highlights the importance of careful endoscopic evaluation of the appendiceal orifice and timely surgical management to prevent complications.

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Cite

BibTeXRIS
BibTeX
@article{nguyen2026when,
  title = {{When the Appendix Speaks: Colonoscopic Recognition of an Appendiceal Mucocele.}},
  author = {Caddie Nguyen and Jackelyn Philip and Lucas Youno and Michael Herman},
  journal = {Cureus},
  year = {2026},
  month = oct,
  doi = {10.7759/cureus.117567},
  url = {https://europepmc.org/article/MED/42996736},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - When the Appendix Speaks: Colonoscopic Recognition of an Appendiceal Mucocele.
AU  - Caddie Nguyen
AU  - Jackelyn Philip
AU  - Lucas Youno
AU  - Michael Herman
PY  - 2026
DA  - 2026/10/06
JO  - Cureus
DO  - 10.7759/cureus.117567
UR  - https://europepmc.org/article/MED/42996736
AB  - Appendiceal mucoceles are rare, often asymptomatic lesions caused by mucin accumulation within the appendix and carry a risk of rupture leading to pseudomyxoma peritonei. We report a case of a 60-year-old man undergoing routine screening colonoscopy in whom a smooth, dome-shaped protrusion of the appendiceal orifice was incidentally identified. No biopsy was performed due to concern for underlying appendiceal pathology. Contrast-enhanced CT revealed a 2.2-cm dilated, fluid-filled appendix consistent with a mucocele. The patient underwent elective laparoscopic appendectomy, and histopathology confirmed a low-grade appendiceal mucinous neoplasm confined to the appendix with negative margins. This case highlights the importance of careful endoscopic evaluation of the appendiceal orifice and timely surgical management to prevent complications.
SN  - 2168-8184
ER  -