Skip to content
DraconiticResearch
Search Sources API
182,544 studies31 sourcesUpdated 50 min ago
Peer-reviewedCC BYRevista brasileira de enfermagem

Analysis of factors associated with death in critically ill patients with COVID-19.

  • Maximina de Barros Cunha1
  • Dulce Aparecida Barbosa1
  • Cassiane Dezoti da Fonseca1,2
  • Matheus Santos Moitinho1
  • Julia Yaeko Kawagoe3
  1. 1Universidade Federal de São Paulo. São Paulo, São Paulo, Brazil.
  2. 2Universidade Federal de Sergipe. São Cristóvão, Sergipe, Brazil.
  3. 3Faculdade Israelita de Ciências da Saúde Albert Einstein. São Paulo, São Paulo, Brazil.
Read full textPDFDOICite

Abstract

Objectives

to assess the factors associated with death in critically ill COVID-19 patients.Methods

retrospective cohort of critically ill patients admitted to the Intensive Care Unit and infected with SARS-CoV-2, followed for 30 days, ≥ 18 years old, with a positive nasopharyngeal RT-PCR test for SARS-CoV-2. Descriptive analysis regarding the outcome, chi-square test, and backward stepwise multiple logistic regression model were used to describe predictor variables of sociodemographic and clinical characteristics.Results

715 patients were analyzed, of whom 70.8% (n=507) died and 29.1% (n=209) survived. In the multivariate analysis, death outcome dependent variables, such as age range of 61-80 years, > 80 years, invasive mechanical ventilation, dialysis, corticosteroids, vancomycin, platelets after 24 hours, and other antibiotics, were identified as risk factors, and the ROC curve (AUC=0.904) predicted the proposed model.Conclusions

the multivariate model showed good discriminatory capacity, identifying independent factors associated with death in critically ill COVID-19 patients.

Related

  1. Factors associated with death among hospitalized older adults with COVID-19 in Brazil.
    Luiz Hiroshi Inoue, Wanessa Cristina Baccon, Francielle Renata Danielli Martins Marques +4
    Revista latino-americana de enfermagemPeer-reviewedCC BYFull textInfectious diseaseEurope PMC
  2. Influenza A-associated pulmonary aspergillosis in critically ill patients in the post-COVID-19 era: a multicenter cohort study from China
    Ming Xue, Zijing Zhou, Yali Chao +13
    International Journal of Infectious DiseasesPeer-reviewedCC BYFull textInfectious diseaseDOAJ
  3. Factors associated with mortality among critically ill pediatric patients referred to a tertiary hospital in Indonesia
    Desy Rusmawatiningtyas, Indah Kartika Murni, Dwi Astuti Dharma Putri +3
    PLOS OnePeer-reviewedCC BY 4.0Full textGeneral biologyObstetrics, gynaecology & paediatricsPLOSPMC
  4. Clinical utility of procalcitonin testing in critically Ill COVID-19 patients: a two-center retrospective cohort study
    Mohammad S. Shawaqfeh, Abdulmajeed M. Alshehri, Ohoud Aljuhani +20
    Scientific ReportsPeer-reviewedCC BY-NC-ND 4.0Full textEpidemiology & public healthCrossref
  5. Hospital-acquired pressure injury among COVID-19 patients admitted to the intensive care unit: Frequency and factors associated with injury stage
    Mohammad Haghighi, Siamak Rimaz, Parissa Bagheri Toolaroud +3
    Iranian Journal of Burns and Wound ResearchPeer-reviewedCC BY-NCFull textGeneral medicineDOAJ

Cite

BibTeXRIS
BibTeX
@article{cunha2026analysis,
  title = {{Analysis of factors associated with death in critically ill patients with COVID-19.}},
  author = {Maximina de Barros Cunha and Dulce Aparecida Barbosa and Cassiane Dezoti da Fonseca and Matheus Santos Moitinho and Julia Yaeko Kawagoe},
  journal = {Revista brasileira de enfermagem},
  year = {2026},
  month = oct,
  doi = {10.1590/0034-7167-2025-0378},
  url = {https://europepmc.org/article/MED/42912114},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Analysis of factors associated with death in critically ill patients with COVID-19.
AU  - Maximina de Barros Cunha
AU  - Dulce Aparecida Barbosa
AU  - Cassiane Dezoti da Fonseca
AU  - Matheus Santos Moitinho
AU  - Julia Yaeko Kawagoe
PY  - 2026
DA  - 2026/10/19
JO  - Revista brasileira de enfermagem
DO  - 10.1590/0034-7167-2025-0378
UR  - https://europepmc.org/article/MED/42912114
AB  - Objectives  to assess the factors associated with death in critically ill COVID-19 patients.Methods  retrospective cohort of critically ill patients admitted to the Intensive Care Unit and infected with SARS-CoV-2, followed for 30 days, ≥ 18 years old, with a positive nasopharyngeal RT-PCR test for SARS-CoV-2. Descriptive analysis regarding the outcome, chi-square test, and backward stepwise multiple logistic regression model were used to describe predictor variables of sociodemographic and clinical characteristics.Results  715 patients were analyzed, of whom 70.8% (n=507) died and 29.1% (n=209) survived. In the multivariate analysis, death outcome dependent variables, such as age range of 61-80 years, > 80 years, invasive mechanical ventilation, dialysis, corticosteroids, vancomycin, platelets after 24 hours, and other antibiotics, were identified as risk factors, and the ROC curve (AUC=0.904) predicted the proposed model.Conclusions  the multivariate model showed good discriminatory capacity, identifying independent factors associated with death in critically ill COVID-19 patients.
SN  - 0034-7167
SN  - 1984-0446
ER  -