REGIONAL PROFILE AND TEMPORAL TRENDS OF HOSPITALIZATIONS AND DEATHS DUE TO DISEASES OF THE BLOOD, BLOOD-FORMING ORGANS, AND IMMUNE DISORDERS IN BRAZIL

@article{silva2026regional,
  title = {{REGIONAL PROFILE AND TEMPORAL TRENDS OF HOSPITALIZATIONS AND DEATHS DUE TO DISEASES OF THE BLOOD, BLOOD-FORMING ORGANS, AND IMMUNE DISORDERS IN BRAZIL}},
  author = {Carlos Eduardo Leitão SILVA and Regiane Santana Conceição Ferreira CABANHA and Josyanne Torres REIS and Danielly Camily Pereira CABANHA and Gustavo Barbosa SOUZA and Priscila Lucindo SILVA and Mamud Alli MURAD and Valter Aragão NASCIMENTO},
  journal = {Hematology, Transfusion and Cell Therapy},
  year = {2026},
  month = oct,
  doi = {10.1016/j.htct.2026.106807},
  url = {https://doi.org/10.1016/j.htct.2026.106807},
  note = {CC BY},
}

TY  - JOUR
TI  - REGIONAL PROFILE AND TEMPORAL TRENDS OF HOSPITALIZATIONS AND DEATHS DUE TO DISEASES OF THE BLOOD, BLOOD-FORMING ORGANS, AND IMMUNE DISORDERS IN BRAZIL
AU  - Carlos Eduardo Leitão SILVA
AU  - Regiane Santana Conceição Ferreira CABANHA
AU  - Josyanne Torres REIS
AU  - Danielly Camily Pereira CABANHA
AU  - Gustavo Barbosa SOUZA
AU  - Priscila Lucindo SILVA
AU  - Mamud Alli MURAD
AU  - Valter Aragão NASCIMENTO
PY  - 2026
DA  - 2026/10/23
JO  - Hematology, Transfusion and Cell Therapy
DO  - 10.1016/j.htct.2026.106807
UR  - https://doi.org/10.1016/j.htct.2026.106807
AB  - Background: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism comprise a heterogeneous group of conditions that may require hospital care and present different patterns of morbidity and mortality across Brazilian regions. The analysis of hospital data allows for the identification of temporal trends and inequalities in service utilization and hospital outcomes. Objective: To analyze the regional distribution and temporal evolution of hospitalizations and deaths related to diseases of the blood and blood-forming organs and immune disorders in Brazil, between 2020 and 2025. Methods: An observational, ecological, retrospective, descriptive, and quantitative study, conducted by consulting the Hospital Information System of the Unified Health System (SIH/SUS). Data regarding ICD-10 Chapter III (Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism) were selected, considering the period from January 2020 to 2025. The variables analyzed were year of care, region of residence, number of hospitalizations, and number of deaths. Hospital mortality was calculated by the ratio between deaths and hospitalizations, multiplied by 100. Descriptive analyses of absolute frequencies, proportional distribution, and temporal evolution of the indicators were performed. Because it uses public, aggregated data without individual identification, there was no access to patients' personal information.Results: In the analyzed period, 709,955 hospitalizations and 35,248 deaths were recorded due to diseases belonging to Chapter III of the ICD-10. An increase in hospitalizations was observed, from 91,140 in 2020 to 134,684 in 2025, representing a 47.8% growth. In the same period, deaths increased from 4,701 to 6,281, corresponding to a 33.6% increment. Hospital mortality decreased from 5.16% in 2020 to 4.66% in 2025. The Southeast region concentrated the highest number of hospitalizations (315,781; 44.5%) and deaths (17,772; 50.4%), followed by the Northeast, with 171,601 hospitalizations and 8,179 deaths. The highest cumulative hospital mortality was observed in the Southeast (5.63%), followed by the Northeast (4.77%) and South (4.68%), while the North (3.61%) and Central-West (3.68%) presented lower proportions. Discussion: The results demonstrate an absolute increase in deaths. However, the growth in hospitalizations was proportionally higher than that of deaths, resulting in a reduction in hospital mortality over the series. The concentration of hospitalizations and deaths in the Southeast may be related to population distribution, a greater supply and concentration of specialized services, and regional diagnostic and hospital capacity. The differences observed between the regions should, however, be interpreted with caution, considering demographic, epidemiological, and socioeconomic characteristics, as well as differences in access to health services. Conclusion: Therefore, an increase in hospitalizations and deaths related to diseases of the blood and blood-forming organs and immune disorders in the SUS is observed, concurrently with a reduction in proportional hospital mortality. The Southeast region presented the highest concentration of hospitalizations and deaths, and the highest cumulative hospital mortality. These findings reinforce the need to track regional and temporal hospital metrics to support care planning and health service organization.
SN  - 2531-1379
SN  - 2531-1387
ER  -