Surgical management of Crohn's disease: current status and challenges

Abstract

Crohn's disease is a chronic, transmural, and progressive inflammatory bowel disease characterized by cumulative structural damage and a high rate of recurrence. Although biologic agents have achieved considerable success in controlling inflammation, a substantial proportion of patients still require surgical intervention. In recent years, the treat-to-target concept—emphasizing objective control of inflammation and prevention of structural damage—has been progressively incorporated into the comprehensive management framework for Crohn's disease. Accordingly, surgery should no longer be viewed simply as a last resort after medical treatment failure. From the perspective of treat-to-target, this review evaluates the current status and challenges of surgical management in Crohn's disease, explores optimization and individualization of treatment decisions, and analyzes other important clinical management approaches and strategies.

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BibTeX RIS

BibTeX

@article{zhuoziqi2026surgical,
  title = {{Surgical management of Crohn's disease: current status and challenges}},
  author = {Qiu Zhuoziqi and Chen Zhihui and Chen Chuangqi},
  journal = {结直肠肛门外科},
  year = {2026},
  month = aug,
  doi = {10.19668/j.cnki.issn1674-0491.2026.04.003},
  url = {https://doi.org/10.19668/j.cnki.issn1674-0491.2026.04.003},
  note = {CC BY-NC-ND},
}

RIS

TY  - JOUR
TI  - Surgical management of Crohn's disease: current status and challenges
AU  - Qiu Zhuoziqi
AU  - Chen Zhihui
AU  - Chen Chuangqi
PY  - 2026
DA  - 2026/08/01
JO  - 结直肠肛门外科
DO  - 10.19668/j.cnki.issn1674-0491.2026.04.003
UR  - https://doi.org/10.19668/j.cnki.issn1674-0491.2026.04.003
AB  - Crohn's disease is a chronic, transmural, and progressive inflammatory bowel disease characterized by cumulative structural damage and a high rate of recurrence. Although biologic agents have achieved considerable success in controlling inflammation, a substantial proportion of patients still require surgical intervention. In recent years, the treat-to-target concept—emphasizing objective control of inflammation and prevention of structural damage—has been progressively incorporated into the comprehensive management framework for Crohn's disease. Accordingly, surgery should no longer be viewed simply as a last resort after medical treatment failure. From the perspective of treat-to-target, this review evaluates the current status and challenges of surgical management in Crohn's disease, explores optimization and individualization of treatment decisions, and analyzes other important clinical management approaches and strategies.
SN  - 1674-0491
ER  -

Abstract

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