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Peer-reviewedCC BY 4.0HIV Medicine

Wellbeing of trans and gender‐diverse people with HIV in the United Kingdom: Results from Positive Voices 2022

238 more authors

60 listed; 250 in total.

8 affiliations
  1. 1UK Health Security Agency London UK
  2. 2Wessex School of Public Health Southampton UK
  3. 3CliniQ London UK
  4. 4Institute for Global Health, University College London London UK
  5. 5George House Trust Manchester UK
  6. 6Royal Berkshire NHS Foundation Trust Reading UK
  7. 7New South Wales Health Coffs Harbour Australia
  8. 8Royal Free London NHS Foundation Trust London UK

Abstract

Objectives: This national cross‐sectional observational study aimed to assess mental health, quality of life, supportive network, experiences of HIV‐related stigma in healthcare and unmet service need among trans and gender‐diverse people with HIV, compared to cisgender people with HIV.

Methods: Positive Voices 2022 is a questionnaire survey of people accessing HIV care in England, Scotland and Wales carried out in 2022 and 2023 that included measures of depression and anxiety symptoms and suicidal ideation (PHQ‐9 and GAD‐7), health‐related quality of life (EQ‐5D‐5L), supportive network (modified Duke FSSQ), experiences of HIV‐related stigma in healthcare and service needs. Logistic and ordinal logistic regression assessed the association of gender identity with these measures unadjusted and adjusted for age group and ethnicity.

Results: Overall, 67 trans or gender‐diverse and 4551 cisgender people with HIV participated. Compared to cisgender participants, trans and gender‐diverse participants were younger, more likely to be Asian and less likely to be black. They were less likely to be in employment, homeowners and financially secure. Trans and gender‐diverse participants had a higher prevalence of depression symptoms (35.5% [22/62] vs. 20.5% [865/4219], adjusted odds ratio [aOR] [95% confidence interval, CI] = 1.96 [1.15, 3.34]; p = 0.014) and suicidal ideation (37.1% [23/62] vs. 14.6% [616/4219]; aOR = 3.09 [1.85, 5.17]; p < 0.001) compared to cisgender participants. They also had poorer health‐related quality of life for three domains (anxiety and depression, usual activities and self‐care) and lower levels of supportive network in unadjusted and adjusted analyses. A higher proportion of trans and gender‐diverse participants than cisgender participants had unmet needs for health services, including mental health services (49.2% [31/63] vs. 30.2% [1310/4343]; aOR = 2.02 [1.22–3.35]; p = 0.007), lifestyle services, and welfare and social services.

Conclusions: Trans and gender‐diverse people with HIV have poorer mental health and wellbeing than cisgender people with HIV, and a higher prevalence of unmet service needs, highlighting the need for access to culturally competent mental health and other health and welfare services.

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BibTeX
@article{kitt2026wellbeing,
  title = {{Wellbeing of trans and gender‐diverse people with HIV in the United Kingdom: Results from Positive Voices 2022}},
  author = {H. Kitt and C. Kelly and A. Aghaizu and M. Ross and F. C. Lampe and C. J. Smith and V. Martin and C. Humphreys and A. Brown and A. Sparrowhawk and M. Kall and J. Sewell and E. Wainwright and V. Delpech and G. Davis and A. Farah and A. Fasanya and A. J. Rodger and T. Đuretić and Ann Sullivan and Ann Sullivan and Rachel Jones and Mohammed Hassan and Serge Miodragovic and Ann Sullivan and Victoria Tittle and Mohammed Hassan and Serge Miodragovic and Sarah Edwards and Melanie Rosenvinge and Allison Mascagni and Rosa Harrington and Claudia Adade and Emily Clarke and Sandra Mason and Emily Clarke and Elaine Priest and Emily Clarke and Sandra Mason and Emily Clarke and Elaine Priest and Emily Clarke and Melissa Martin and Athavan Umaipalan and Julie Field and Clare Woodward and Felicity Williams and Liz Hamlyn and Lucy Campbell and Steve Taylor and Gerry Gilleran and Satwant Kaur and Cathy Ormiston and Laura Wilson‐Powell and Kate Saunders and Meena Gupta and Julia Ball and Mark Gompels and Louise Jennings and Malgorzata Slowinska},
  journal = {HIV Medicine},
  year = {2026},
  month = aug,
  doi = {10.1111/hiv.70286},
  url = {https://doi.org/10.1111/hiv.70286},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Wellbeing of trans and gender‐diverse people with HIV in the United Kingdom: Results from Positive Voices 2022
AU  - H. Kitt
AU  - C. Kelly
AU  - A. Aghaizu
AU  - M. Ross
AU  - F. C. Lampe
AU  - C. J. Smith
AU  - V. Martin
AU  - C. Humphreys
AU  - A. Brown
AU  - A. Sparrowhawk
AU  - M. Kall
AU  - J. Sewell
AU  - E. Wainwright
AU  - V. Delpech
AU  - G. Davis
AU  - A. Farah
AU  - A. Fasanya
AU  - A. J. Rodger
AU  - T. Đuretić
AU  - Ann Sullivan
AU  - Ann Sullivan
AU  - Rachel Jones
AU  - Mohammed Hassan
AU  - Serge Miodragovic
AU  - Ann Sullivan
AU  - Victoria Tittle
AU  - Mohammed Hassan
AU  - Serge Miodragovic
AU  - Sarah Edwards
AU  - Melanie Rosenvinge
AU  - Allison Mascagni
AU  - Rosa Harrington
AU  - Claudia Adade
AU  - Emily Clarke
AU  - Sandra Mason
AU  - Emily Clarke
AU  - Elaine Priest
AU  - Emily Clarke
AU  - Sandra Mason
AU  - Emily Clarke
AU  - Elaine Priest
AU  - Emily Clarke
AU  - Melissa Martin
AU  - Athavan Umaipalan
AU  - Julie Field
AU  - Clare Woodward
AU  - Felicity Williams
AU  - Liz Hamlyn
AU  - Lucy Campbell
AU  - Steve Taylor
AU  - Gerry Gilleran
AU  - Satwant Kaur
AU  - Cathy Ormiston
AU  - Laura Wilson‐Powell
AU  - Kate Saunders
AU  - Meena Gupta
AU  - Julia Ball
AU  - Mark Gompels
AU  - Louise Jennings
AU  - Malgorzata Slowinska
PY  - 2026
DA  - 2026/08/27
JO  - HIV Medicine
DO  - 10.1111/hiv.70286
UR  - https://doi.org/10.1111/hiv.70286
AB  - Objectives: This national cross‐sectional observational study aimed to assess mental health, quality of life, supportive network, experiences of HIV‐related stigma in healthcare and unmet service need among trans and gender‐diverse people with HIV, compared to cisgender people with HIV.  Methods: Positive Voices 2022 is a questionnaire survey of people accessing HIV care in England, Scotland and Wales carried out in 2022 and 2023 that included measures of depression and anxiety symptoms and suicidal ideation (PHQ‐9 and GAD‐7), health‐related quality of life (EQ‐5D‐5L), supportive network (modified Duke FSSQ), experiences of HIV‐related stigma in healthcare and service needs. Logistic and ordinal logistic regression assessed the association of gender identity with these measures unadjusted and adjusted for age group and ethnicity.  Results: Overall, 67 trans or gender‐diverse and 4551 cisgender people with HIV participated. Compared to cisgender participants, trans and gender‐diverse participants were younger, more likely to be Asian and less likely to be black. They were less likely to be in employment, homeowners and financially secure. Trans and gender‐diverse participants had a higher prevalence of depression symptoms (35.5% [22/62] vs. 20.5% [865/4219], adjusted odds ratio [aOR] [95% confidence interval, CI] = 1.96 [1.15, 3.34]; p = 0.014) and suicidal ideation (37.1% [23/62] vs. 14.6% [616/4219]; aOR = 3.09 [1.85, 5.17]; p < 0.001) compared to cisgender participants. They also had poorer health‐related quality of life for three domains (anxiety and depression, usual activities and self‐care) and lower levels of supportive network in unadjusted and adjusted analyses. A higher proportion of trans and gender‐diverse participants than cisgender participants had unmet needs for health services, including mental health services (49.2% [31/63] vs. 30.2% [1310/4343]; aOR = 2.02 [1.22–3.35]; p = 0.007), lifestyle services, and welfare and social services.  Conclusions: Trans and gender‐diverse people with HIV have poorer mental health and wellbeing than cisgender people with HIV, and a higher prevalence of unmet service needs, highlighting the need for access to culturally competent mental health and other health and welfare services.
SN  - 1464-2662
SN  - 1468-1293
ER  -