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Peer-reviewedCC BYBrazilian journal of otorhinolaryngology

Orbitocranial resection for treatment of lacrimal gland malignant tumors with intracranial extension.

  • Ying Xia1
  • Yan Sui1
  • Guo-Chao Zhang1
  • Si-Yi Yang2
  • Wen-Fu Lu1
  • Ping-An Wu3
  1. 1Division of Head and Neck Surgery, Department of Surgery, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, P.R. China; School of Medicine, Shenzhen University, Shenzhen, Guangdong, P.R. China.
  2. 2Division of Head and Neck Surgery, Department of Surgery, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, P.R. China.
  3. 3Division of Head and Neck Surgery, Department of Surgery, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, P.R. China. Electronic address: [email protected].
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Abstract

Objectives

This study reports our experience with multidisciplinary surgical management of lacrimal gland malignant tumors with intracranial extension using the orbitocranial approach.Methods

We reviewed treatment strategies and surgical approaches for lacrimal gland malignant tumors with intracranial extension and present 2 illustrative patients who underwent orbitocranial resection at our institution in 2015. Clinical records, radiographic images, histologic sections, and archived pathology specimens were reviewed.Results

Both patients underwent orbitocranial tumor resection, followed by postoperative chemoradiotherapy. Orbital reconstruction was performed using a temporalis fascia flap and split calvarial bone grafts, with split-thickness skin grafting to line the orbital cavity. The follow-up periods were 69- and 66-months, respectively. Both patients remained alive without evidence of disease recurrence during follow-up.Conclusions

The orbitocranial approach, combined with postoperative chemoradiotherapy, may provide satisfactory local and regional control in selected patients with lacrimal gland malignant tumors with intracranial extension. Long-term surveillance remains important because patients may remain at risk for disease recurrence or distant metastasis.

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Cite

BibTeXRIS
BibTeX
@article{xia2026orbitocranial,
  title = {{Orbitocranial resection for treatment of lacrimal gland malignant tumors with intracranial extension.}},
  author = {Ying Xia and Yan Sui and Guo-Chao Zhang and Si-Yi Yang and Wen-Fu Lu and Ping-An Wu},
  journal = {Brazilian journal of otorhinolaryngology},
  year = {2026},
  month = oct,
  doi = {10.1016/j.bjorl.2026.101921},
  url = {https://europepmc.org/article/MED/42874303},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Orbitocranial resection for treatment of lacrimal gland malignant tumors with intracranial extension.
AU  - Ying Xia
AU  - Yan Sui
AU  - Guo-Chao Zhang
AU  - Si-Yi Yang
AU  - Wen-Fu Lu
AU  - Ping-An Wu
PY  - 2026
DA  - 2026/10/14
JO  - Brazilian journal of otorhinolaryngology
DO  - 10.1016/j.bjorl.2026.101921
UR  - https://europepmc.org/article/MED/42874303
AB  - Objectives  This study reports our experience with multidisciplinary surgical management of lacrimal gland malignant tumors with intracranial extension using the orbitocranial approach.Methods  We reviewed treatment strategies and surgical approaches for lacrimal gland malignant tumors with intracranial extension and present 2 illustrative patients who underwent orbitocranial resection at our institution in 2015. Clinical records, radiographic images, histologic sections, and archived pathology specimens were reviewed.Results  Both patients underwent orbitocranial tumor resection, followed by postoperative chemoradiotherapy. Orbital reconstruction was performed using a temporalis fascia flap and split calvarial bone grafts, with split-thickness skin grafting to line the orbital cavity. The follow-up periods were 69- and 66-months, respectively. Both patients remained alive without evidence of disease recurrence during follow-up.Conclusions  The orbitocranial approach, combined with postoperative chemoradiotherapy, may provide satisfactory local and regional control in selected patients with lacrimal gland malignant tumors with intracranial extension. Long-term surveillance remains important because patients may remain at risk for disease recurrence or distant metastasis.
SN  - 1808-8694
SN  - 1808-8686
ER  -