Comparison of Effects of Pulsed Field Ablation and Cryoablation on Left Atrial Stiffness Using Invasively Derived Pressure–Volume Relationship
- 1First Department of Cardiology National and Kapodistrian University of Athens, “Hippokration” G.H.A. Athens Greece
Abstract
Background: Acute effects of pulsed field ablation (PFA) on passive atrial mechanical properties have not hitherto been assessed by reconstruction of pressure–volume relationship using invasive intracavitary pressure measurements.
Methods: In a cohort of 38 first‐time atrial fibrillation ablation patients, submitted to pulmonary vein isolation, we studied the effects of PFA and cryoballoon ablation on the left atrial elastic constant and passive elastic chamber stiffness constant, expressing baseline left atrial conditions and quantifying passive left atrial stiffness, respectively. Left atrial pressure was invasively measured immediately pre‐ and post‐procedurally, while volume values were obtained echocardiographically.
Results: No differences were noted in passive elastic chamber stiffness constant values, pre‐ and post‐procedurally in either group. No differences were noted between CBA and PFA groups. There were no observable associations between Δα and Δb and either AF duration or preprocedural left atrial volume.
Conclusions: Based on the above, CBA and PFA demonstrated comparable effects on left atrial mechanical properties in the acute post‐ablation setting.
Related
- Dose–effect relationship of an acute isometric exercise session with different durations on blood pressure and arterial stiffness in prehypertensive substance use disorder individuals
- Vagal Response and Cough Reflex During Atrial Fibrillation Ablation Under Deep Sedation: A Comparison Across Pulsed Field Ablation Systems.
- Device-dependent activated clotting time measurements during transseptal ablation under continuous anticoagulation: Comparison of mechanical-optical and microfluidic electrochemical systems.
- Atrial fibrillation cryoablation complicated by diffuse coronary artery vasospasm and cardiac arrest: a case report
- Examining the relationship between temperature and firearm violence: A comparison of metrics
BibTeX
@article{antoniou2026comparison,
title = {{Comparison of Effects of Pulsed Field Ablation and Cryoablation on Left Atrial Stiffness Using Invasively Derived Pressure–Volume Relationship}},
author = {Christos‐Konstantinos Antoniou and Dimitris Tsiachris and Aikaterini‐Eleftheria Karanikola and Michail Botis and Athanasios Kordalis and Ioannis Doundoulakis and Panagiotis Xydis and Dimitrios Klettas and Christina Chrysohoou and Konstantinos P. Tsioufis},
journal = {Journal of Arrhythmia},
year = {2026},
month = nov,
doi = {10.1002/joa3.70520},
url = {https://doi.org/10.1002/joa3.70520},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Comparison of Effects of Pulsed Field Ablation and Cryoablation on Left Atrial Stiffness Using Invasively Derived Pressure–Volume Relationship
AU - Christos‐Konstantinos Antoniou
AU - Dimitris Tsiachris
AU - Aikaterini‐Eleftheria Karanikola
AU - Michail Botis
AU - Athanasios Kordalis
AU - Ioannis Doundoulakis
AU - Panagiotis Xydis
AU - Dimitrios Klettas
AU - Christina Chrysohoou
AU - Konstantinos P. Tsioufis
PY - 2026
DA - 2026/11/05
JO - Journal of Arrhythmia
DO - 10.1002/joa3.70520
UR - https://doi.org/10.1002/joa3.70520
AB - Background: Acute effects of pulsed field ablation (PFA) on passive atrial mechanical properties have not hitherto been assessed by reconstruction of pressure–volume relationship using invasive intracavitary pressure measurements. Methods: In a cohort of 38 first‐time atrial fibrillation ablation patients, submitted to pulmonary vein isolation, we studied the effects of PFA and cryoballoon ablation on the left atrial elastic constant and passive elastic chamber stiffness constant, expressing baseline left atrial conditions and quantifying passive left atrial stiffness, respectively. Left atrial pressure was invasively measured immediately pre‐ and post‐procedurally, while volume values were obtained echocardiographically. Results: No differences were noted in passive elastic chamber stiffness constant values, pre‐ and post‐procedurally in either group. No differences were noted between CBA and PFA groups. There were no observable associations between Δα and Δb and either AF duration or preprocedural left atrial volume. Conclusions: Based on the above, CBA and PFA demonstrated comparable effects on left atrial mechanical properties in the acute post‐ablation setting.
SN - 1880-4276
SN - 1883-2148
ER -