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Peer-reviewedCC BYRadiology case reports

Klebsiella pneumoniae pyogenic liver abscess mimicking hepatic malignancy in a non-diabetic patient: A case report from Kazakhstan.

  • Gaukhar Medetova1
  • Davranbek Abduvaliyev1
  • Arailym Kizayeva1
  • Ayaulym Gabbassova1
  • Indira Bozheyeva1
  1. 1Scientific Research Institute of Radiology named after Zh. H. Khamzabayev, Astana Medical University, Beibitshilik 49A, Astana, 010000, Kazakhstan.
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Abstract

Pyogenic liver abscess is an infectious condition associated with significant morbidity and mortality, with Klebsiella pneumoniae emerging as a major pathogen. We report a case of Klebsiella pneumoniae pyogenic liver abscess in a 76-year-old woman from Kazakhstan, representing one of the first indexed reports from Central Asia. The patient presented with prolonged fever, jaundice, and constitutional symptoms without diabetes mellitus. Initial ultrasound revealed a large heterogeneous hepatic mass with a solid, tumor-like appearance, raising concern for malignancy in the setting of chronic hepatitis B infection. MRI and contrast-enhanced CT demonstrated diffusion restriction, multiloculated architecture, and mild peripheral and septal enhancement without arterial hyperenhancement or venous washout, favoring hepatic abscess over hepatocellular carcinoma. The solid, tumor-like ultrasound appearance, atypical for a pyogenic abscess in its resemblance to hepatic malignancy, posed the primary diagnostic challenge, underscoring the value of multimodal imaging in characterizing hepatic lesions. Additionally, KPLA should be considered in the differential diagnosis even in the absence of classical metabolic risk factors and in regions with limited epidemiological data.

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Cite

BibTeXRIS
BibTeX
@article{medetova2026klebsiella,
  title = {{Klebsiella pneumoniae pyogenic liver abscess mimicking hepatic malignancy in a non-diabetic patient: A case report from Kazakhstan.}},
  author = {Gaukhar Medetova and Davranbek Abduvaliyev and Arailym Kizayeva and Ayaulym Gabbassova and Indira Bozheyeva},
  journal = {Radiology case reports},
  year = {2026},
  month = oct,
  doi = {10.1016/j.radcr.2026.09.056},
  url = {https://europepmc.org/article/MED/42927162},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Klebsiella pneumoniae pyogenic liver abscess mimicking hepatic malignancy in a non-diabetic patient: A case report from Kazakhstan.
AU  - Gaukhar Medetova
AU  - Davranbek Abduvaliyev
AU  - Arailym Kizayeva
AU  - Ayaulym Gabbassova
AU  - Indira Bozheyeva
PY  - 2026
DA  - 2026/10/15
JO  - Radiology case reports
DO  - 10.1016/j.radcr.2026.09.056
UR  - https://europepmc.org/article/MED/42927162
AB  - Pyogenic liver abscess is an infectious condition associated with significant morbidity and mortality, with Klebsiella pneumoniae emerging as a major pathogen. We report a case of Klebsiella pneumoniae pyogenic liver abscess in a 76-year-old woman from Kazakhstan, representing one of the first indexed reports from Central Asia. The patient presented with prolonged fever, jaundice, and constitutional symptoms without diabetes mellitus. Initial ultrasound revealed a large heterogeneous hepatic mass with a solid, tumor-like appearance, raising concern for malignancy in the setting of chronic hepatitis B infection. MRI and contrast-enhanced CT demonstrated diffusion restriction, multiloculated architecture, and mild peripheral and septal enhancement without arterial hyperenhancement or venous washout, favoring hepatic abscess over hepatocellular carcinoma. The solid, tumor-like ultrasound appearance, atypical for a pyogenic abscess in its resemblance to hepatic malignancy, posed the primary diagnostic challenge, underscoring the value of multimodal imaging in characterizing hepatic lesions. Additionally, KPLA should be considered in the differential diagnosis even in the absence of classical metabolic risk factors and in regions with limited epidemiological data.
SN  - 1930-0433
ER  -