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Peer-reviewedCC BY-NC-NDJournal of medical case reports

Thyroid nodule treated by herbal food composite formulation: a case report.

4 affiliations
  1. 1MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, 200438, China.
  2. 2MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, 200438, China. [email protected].
  3. 3Nanyang Academy of Life Sciences, Singapore, 069533, Singapore. [email protected].
  4. 4Changbassan Institute of Tåisuĭ, Baishan, Jilin, 134700, China. [email protected].

Abstract

Background

Thyroid nodules are a prevalent endocrine disorder with a global prevalence estimated to range from 5% to 67%. Conventional treatments, including surveillance, levothyroxine suppression therapy, and surgical resection, are often limited by side effects, invasiveness, and variable efficacy. To date, documented instances of spontaneous regression are exceedingly rare.Case presentation

In this case report, we present a 48-year-old Chinese Asian woman with bilateral thyroid nodules who experienced significant nodule regression after a 3.5-month intervention with herbal food composite formulation. The formula, comprising Aronia melanocarpa, Daucus carota, Apium graveolens, Citrus paradisi, and Litchi chinensis, was consumed as juice every other day post-lunch. The patient's ultrasound examination showed multiple mixed echogenic nodules in both thyroid lobes, with the largest nodule measuring 20.7 × 10.4 mm. After treatment, the nodules significantly decreased in size, and a lymph node in the left neck disappeared.Conclusions

This case raises the possibility that the herbal food composite formulation may have potential value to be explored as an auxiliary therapy for thyroid nodules, warranting further investigation in larger patient populations.

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BibTeX
@article{you2026thyroid,
  title = {{Thyroid nodule treated by herbal food composite formulation: a case report.}},
  author = {Yi You and Hui Li},
  journal = {Journal of medical case reports},
  year = {2026},
  month = jul,
  doi = {10.1186/s13256-026-06392-2},
  url = {https://europepmc.org/article/MED/42902354},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Thyroid nodule treated by herbal food composite formulation: a case report.
AU  - Yi You
AU  - Hui Li
PY  - 2026
DA  - 2026/07/01
JO  - Journal of medical case reports
DO  - 10.1186/s13256-026-06392-2
UR  - https://europepmc.org/article/MED/42902354
AB  - Background  Thyroid nodules are a prevalent endocrine disorder with a global prevalence estimated to range from 5% to 67%. Conventional treatments, including surveillance, levothyroxine suppression therapy, and surgical resection, are often limited by side effects, invasiveness, and variable efficacy. To date, documented instances of spontaneous regression are exceedingly rare.Case presentation  In this case report, we present a 48-year-old Chinese Asian woman with bilateral thyroid nodules who experienced significant nodule regression after a 3.5-month intervention with herbal food composite formulation. The formula, comprising Aronia melanocarpa, Daucus carota, Apium graveolens, Citrus paradisi, and Litchi chinensis, was consumed as juice every other day post-lunch. The patient's ultrasound examination showed multiple mixed echogenic nodules in both thyroid lobes, with the largest nodule measuring 20.7 × 10.4 mm. After treatment, the nodules significantly decreased in size, and a lymph node in the left neck disappeared.Conclusions  This case raises the possibility that the herbal food composite formulation may have potential value to be explored as an auxiliary therapy for thyroid nodules, warranting further investigation in larger patient populations.
SN  - 1752-1947
ER  -