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Peer-reviewedCC BY 4.0Frontiers in Public Health

Factors influencing childhood vaccine hesitancy and interventions for parents and caregivers from ethnic minority backgrounds in the United Kingdom to encourage uptake: a systematic review

7 more authors
17 affiliations
  1. 1Division of Psychology and Mental Health, University of Manchester, Manchester, United Kingdom
  2. 2School of Social Sciences, Humanities and Law, Teesside University, Middlesbrough, United Kingdom
  3. 3Department of Economics, Faculty of the Social Sciences, Delta State University, Abraka, Nigeria
  4. 4Department of Psychology, Delta State University, Abraka, Nigeria
  5. 5Department of Haematology/ Chief Medical Centre, University of Calabar, Calabar, Nigeria
  6. 6Federal Medical Centre, Ovwian, Nigeria
  7. 7School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia
  8. 8The Leprosy Mission International, Ethiopia, Ethiopia
  9. 9Western Governors University, Salt Lake City, UT, United States
  10. 10Manchester Global Foundation, London, United Kingdom
  11. 11Tare Wyd Legal Chambers, Warri, Nigeria
  12. 12Beryl Foundation, London, United Kingdom
  13. 13University College London, London, United Kingdom
  14. 14Department of Public Health, University of Delta, Agbor, Delta, Nigeria
  15. 15School of Social Policy, University of Birmingham, Birmingham, United Kingdom
  16. 16Department of Community Medicine, Delta State University Teaching Hospital, Oghara, Delta, Nigeria
  17. 17Mersey Care NHS Foundation Trust, Liverpool, United Kingdom

Abstract

Background: Childhood vaccine hesitancy remains a significant public health concern, especially as it relates to ethnic minority population in the United Kingdom, who are reluctant to engage in uptake and record a higher number of unvaccinated children. Yet, there remains a significant research gap on the factors driving ethnic minorities parental hesitancy of childhood vaccination and interventions to improve uptake for the affected population in the UK, which is the primary aim and contribution of the present review.

Method: The review strategy was underpinned by the Population, phenomenon of Interest and Context (PICo) model. Hence, the Population (parents and caregivers from ethnic minority backgrounds), the phenomenon of Interest (factors fostering parental childhood vaccine hesitancy and interventions to encourage uptake), and the Context (Vaccine hesitancy). For qualitative studies, the PICo strategy, which is a modified version of PICO, was used. Boolean operators (AND/OR/NOT) were used to ensure rigor and were adopted in the formulation of search terms. Eight databases were searched (PubMed, CINAHL, the Cochrane Controlled Trial Register, Embase, Web of Science, PsycINFO, ProQuest Central, and Scopus) for published articles between 2002 and June 2026. N = 10 studies met the inclusion criteria, and the relevant data were synthesized using a thematic synthesis approach. The review protocol was pre-registered on the PROSPERO Registry (no. CRD420261358747).

Findings: The synthesized studies and analyses yielded the following main findings. (i) Skepticism about vaccines, (ii) Distrust in health professionals and policy, (iii) Poor understanding and limited information about vaccines, (iv) Social network and family influence and (v) communication-based intervention.

Conclusion: Childhood vaccine hesitancy remains a challenge; the review recommends culturally adapted public health promotion messages and interventions to encourage uptake, to be tested using randomized controlled trials.

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BibTeX
@article{ike2026factors,
  title = {{Factors influencing childhood vaccine hesitancy and interventions for parents and caregivers from ethnic minority backgrounds in the United Kingdom to encourage uptake: a systematic review}},
  author = {Tarela Juliet Ike and Dung Ezekiel Jidong and Callistar Kidochukwu Obi and Chiyem Lucky Nwanzu and Akaba Kingsley and Mulugeta Tamire and Marekegn Habtamu and Mieyebi Lawrence Ike and Evangelyn Ebi Ayobi and Peremi Richmond Ike and Rukevwe Francis Doghor and Rakhshi Memon and Kelvin Odeyovwi Ayobi and Aboneh Solomon Sime and Otovwe Agofure and Jo Parsons and Sarah Edwards and Maureen Iru Ntaji and Nusrat Husain},
  journal = {Frontiers in Public Health},
  year = {2026},
  month = oct,
  doi = {10.3389/fpubh.2026.1929472},
  url = {https://doi.org/10.3389/fpubh.2026.1929472},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Factors influencing childhood vaccine hesitancy and interventions for parents and caregivers from ethnic minority backgrounds in the United Kingdom to encourage uptake: a systematic review
AU  - Tarela Juliet Ike
AU  - Dung Ezekiel Jidong
AU  - Callistar Kidochukwu Obi
AU  - Chiyem Lucky Nwanzu
AU  - Akaba Kingsley
AU  - Mulugeta Tamire
AU  - Marekegn Habtamu
AU  - Mieyebi Lawrence Ike
AU  - Evangelyn Ebi Ayobi
AU  - Peremi Richmond Ike
AU  - Rukevwe Francis Doghor
AU  - Rakhshi Memon
AU  - Kelvin Odeyovwi Ayobi
AU  - Aboneh Solomon Sime
AU  - Otovwe Agofure
AU  - Jo Parsons
AU  - Sarah Edwards
AU  - Maureen Iru Ntaji
AU  - Nusrat Husain
PY  - 2026
DA  - 2026/10/12
JO  - Frontiers in Public Health
DO  - 10.3389/fpubh.2026.1929472
UR  - https://doi.org/10.3389/fpubh.2026.1929472
AB  - Background: Childhood vaccine hesitancy remains a significant public health concern, especially as it relates to ethnic minority population in the United Kingdom, who are reluctant to engage in uptake and record a higher number of unvaccinated children. Yet, there remains a significant research gap on the factors driving ethnic minorities parental hesitancy of childhood vaccination and interventions to improve uptake for the affected population in the UK, which is the primary aim and contribution of the present review.  Method: The review strategy was underpinned by the Population, phenomenon of Interest and Context (PICo) model. Hence, the Population (parents and caregivers from ethnic minority backgrounds), the phenomenon of Interest (factors fostering parental childhood vaccine hesitancy and interventions to encourage uptake), and the Context (Vaccine hesitancy). For qualitative studies, the PICo strategy, which is a modified version of PICO, was used. Boolean operators (AND/OR/NOT) were used to ensure rigor and were adopted in the formulation of search terms. Eight databases were searched (PubMed, CINAHL, the Cochrane Controlled Trial Register, Embase, Web of Science, PsycINFO, ProQuest Central, and Scopus) for published articles between 2002 and June 2026. N = 10 studies met the inclusion criteria, and the relevant data were synthesized using a thematic synthesis approach. The review protocol was pre-registered on the PROSPERO Registry (no. CRD420261358747).  Findings: The synthesized studies and analyses yielded the following main findings. (i) Skepticism about vaccines, (ii) Distrust in health professionals and policy, (iii) Poor understanding and limited information about vaccines, (iv) Social network and family influence and (v) communication-based intervention.  Conclusion: Childhood vaccine hesitancy remains a challenge; the review recommends culturally adapted public health promotion messages and interventions to encourage uptake, to be tested using randomized controlled trials.
SN  - 2296-2565
ER  -