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Peer-reviewedCC BY-NC-ND 4.0Catheterization and Cardiovascular Interventions

Feasibility and Procedural Considerations of Balloon‐Expandable TAVR in Patients With Prior Endovascular Aortic Stent Grafts

  1. 1Department of Cardiovascular Disease McGovern Medical School at UTHealth Houston Houston Texas USA
  2. 2Department of Cardiothoracic and Vascular Surgery McGovern Medical School at UTHealth Houston Houston Texas USA

Abstract

Objectives: To evaluate the feasibility and short‐term outcomes of transcatheter aortic valve replacement (TAVR) using balloon‐expandable Sapien valves in patients with prior endovascular aortic stent grafts.

Methods: We conducted a single‐center, retrospective study of 23 patients with prior endovascular aortic stent grafts who underwent TAVR between 2012 and 2025 using Sapien platform balloon‐expandable valves. Descriptive statistics and univariate logistic regression analysis were used to characterize and identify outcomes of peri‐procedural complications.

Results: Transfemoral access was used in 87% of cases, and valve deployment was successful in all patients without aortic injuries or graft‐related complications during the procedural and up to 30‐day post‐procedure period. Median length of stay was 3 days, and there were no deaths up to 30‐days. Post‐procedural events were infrequent and included new‐onset atrial fibrillation (n = 2), transient hemodialysis (n = 1), pleural effusion (n = 1), and stroke (n = 1). In exploratory analyses limited by the small number of events, older age (OR 1.27, 95% CI 1.04–1.71) and higher baseline mean aortic‐valve gradient (OR 1.24, 95% CI 1.06–1.76) were associated with periprocedural events.

Conclusions: The complications observed in our cohort are general outcomes associated with TAVR, instead of graft‐associated outcomes. Balloon‐expandable TAVR is technically safe and feasible in patients with prior endovascular aortic stent grafts when performed at experienced centers.

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BibTeX
@article{alhallak2026feasibility,
  title = {{Feasibility and Procedural Considerations of Balloon‐Expandable TAVR in Patients With Prior Endovascular Aortic Stent Grafts}},
  author = {Iad Alhallak and Alexander Mills and Beau Bequeaith and Ken Chan and Akiko Tanaka and Anthony L. Estrera and Biswajit Kar and Richard Smalling and Abhijeet Dhoble},
  journal = {Catheterization and Cardiovascular Interventions},
  year = {2026},
  month = sep,
  doi = {10.1002/ccd.70867},
  url = {https://doi.org/10.1002/ccd.70867},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - Feasibility and Procedural Considerations of Balloon‐Expandable TAVR in Patients With Prior Endovascular Aortic Stent Grafts
AU  - Iad Alhallak
AU  - Alexander Mills
AU  - Beau Bequeaith
AU  - Ken Chan
AU  - Akiko Tanaka
AU  - Anthony L. Estrera
AU  - Biswajit Kar
AU  - Richard Smalling
AU  - Abhijeet Dhoble
PY  - 2026
DA  - 2026/09/13
JO  - Catheterization and Cardiovascular Interventions
DO  - 10.1002/ccd.70867
UR  - https://doi.org/10.1002/ccd.70867
AB  - Objectives: To evaluate the feasibility and short‐term outcomes of transcatheter aortic valve replacement (TAVR) using balloon‐expandable Sapien valves in patients with prior endovascular aortic stent grafts.  Methods: We conducted a single‐center, retrospective study of 23 patients with prior endovascular aortic stent grafts who underwent TAVR between 2012 and 2025 using Sapien platform balloon‐expandable valves. Descriptive statistics and univariate logistic regression analysis were used to characterize and identify outcomes of peri‐procedural complications.  Results: Transfemoral access was used in 87% of cases, and valve deployment was successful in all patients without aortic injuries or graft‐related complications during the procedural and up to 30‐day post‐procedure period. Median length of stay was 3 days, and there were no deaths up to 30‐days. Post‐procedural events were infrequent and included new‐onset atrial fibrillation (n = 2), transient hemodialysis (n = 1), pleural effusion (n = 1), and stroke (n = 1). In exploratory analyses limited by the small number of events, older age (OR 1.27, 95% CI 1.04–1.71) and higher baseline mean aortic‐valve gradient (OR 1.24, 95% CI 1.06–1.76) were associated with periprocedural events.  Conclusions: The complications observed in our cohort are general outcomes associated with TAVR, instead of graft‐associated outcomes. Balloon‐expandable TAVR is technically safe and feasible in patients with prior endovascular aortic stent grafts when performed at experienced centers.
SN  - 1522-1946
SN  - 1522-726X
ER  -