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Peer-reviewedCC BYFrontiers in physiology

Personalized stress detection from wearable physiological signals via Digital Twin-inspired subject embeddings and recurrent neural networks

  1. 1Department of Artificial Intelligence and Data Science, College of Computer Science and Engineering, University of Ha’il , ,

Abstract

Introduction

The rising prevalence of psychological stress and its associated adverse health effects have created an urgent need for reliable and automated detection methods that move beyond traditional self-report tools. While wearable sensing systems offer a promising avenue for continuous monitoring, current systems often fail to account for individual physiological variability in stress responses. This leads to suboptimal performance when applied across diverse populations. To address this challenge, this paper presents a novel framework aimed at personalized stress detection in wearable sensing systems.Methods

We introduce a DT-GRU framework centered on a trainable subject-embedding module that captures each individual's unique physiological traits, thereby forming a latent Digital Twin (DT). This personalized embedding is integrated with Gated Recurrent Unit (GRU) features in the model's inference pathway, enabling the framework to utilize both temporal dynamics and subject identity for improved detection. The DT-GRU framework was rigorously evaluated on the WESAD dataset, incorporating various validation techniques, including subject-independent train-test splits and Leave-One-Subject-Out (LOSO) cross-validation.Results

The results from the evaluation demonstrate significant improvements in classification accuracy and generalizability. The integration of the personalized subject-embedding was shown to enhance the model's performance across the diverse population represented in the dataset.Discussion

These findings highlight the potential of the DT-GRU approach for deployment in real-world stress monitoring applications. By effectively accounting for individual physiological variability, the framework provides a more reliable and personalized method for automated stress detection, paving the way for more effective and scalable mental health monitoring solutions.

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BibTeX
@article{alharbi2026personalized,
  title = {{Personalized stress detection from wearable physiological signals via Digital Twin-inspired subject embeddings and recurrent neural networks}},
  author = {Hadeel Alharbi},
  journal = {Frontiers in physiology},
  year = {2026},
  month = oct,
  doi = {10.3389/fphys.2026.1881803},
  url = {https://europepmc.org/article/PMC/PMC13717694},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Personalized stress detection from wearable physiological signals via Digital Twin-inspired subject embeddings and recurrent neural networks
AU  - Hadeel Alharbi
PY  - 2026
DA  - 2026/10/15
JO  - Frontiers in physiology
DO  - 10.3389/fphys.2026.1881803
UR  - https://europepmc.org/article/PMC/PMC13717694
AB  - Introduction  The rising prevalence of psychological stress and its associated adverse health effects have created an urgent need for reliable and automated detection methods that move beyond traditional self-report tools. While wearable sensing systems offer a promising avenue for continuous monitoring, current systems often fail to account for individual physiological variability in stress responses. This leads to suboptimal performance when applied across diverse populations. To address this challenge, this paper presents a novel framework aimed at personalized stress detection in wearable sensing systems.Methods  We introduce a DT-GRU framework centered on a trainable subject-embedding module that captures each individual's unique physiological traits, thereby forming a latent Digital Twin (DT). This personalized embedding is integrated with Gated Recurrent Unit (GRU) features in the model's inference pathway, enabling the framework to utilize both temporal dynamics and subject identity for improved detection. The DT-GRU framework was rigorously evaluated on the WESAD dataset, incorporating various validation techniques, including subject-independent train-test splits and Leave-One-Subject-Out (LOSO) cross-validation.Results  The results from the evaluation demonstrate significant improvements in classification accuracy and generalizability. The integration of the personalized subject-embedding was shown to enhance the model's performance across the diverse population represented in the dataset.Discussion  These findings highlight the potential of the DT-GRU approach for deployment in real-world stress monitoring applications. By effectively accounting for individual physiological variability, the framework provides a more reliable and personalized method for automated stress detection, paving the way for more effective and scalable mental health monitoring solutions.
SN  - 1664-042X
ER  -