Skip to content
DraconiticResearch
Search Sources API
197,578 studies31 sourcesUpdated 12 min ago
Peer-reviewedCC BY 4.0Frontiers in Neuroscience

Effect of ultrasound-guided stellate ganglion block on intraoperative hemodynamics in laparoscopic partial adrenalectomy: a randomized clinical trial

  • Jingyi Nie1
  • Huang Wang2
  • Wenjing Zhang1
  • Hui Wang3
  • Pengqian Hao3
  • Junchai Liu3
  • Jiwen Shang4
  • Weiwei Zhang3
4 affiliations
  1. 1Department of Anesthesiology, Shanxi Medical University
  2. 2School of Basic Medical Sciences, Shanxi Medical University
  3. 3Department of Anesthesiology, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital
  4. 4Department of Urology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University
Read full textPDFDOICite

Abstract

Purpose: This study aimed to evaluate the effect of ultrasound-guided stellate ganglion block (SGB) on intraoperative hemodynamic parameters in patients undergoing laparoscopic partial adrenalectomy.

Patients and methods: A total of 72 patients with adrenal tumors scheduled for laparoscopic partial adrenalectomy were enrolled and randomly assigned in a 1:1 ratio to either the stellate ganglion block (SGB) group or the control group. The primary outcome was the incidence of intraoperative hypertension, defined as a systolic blood pressure (SBP) ≥180 mmHg or an increase of ≥30% in mean arterial pressure (MAP) from baseline. Secondary outcomes included MAP and heart rate (HR) measured at nine predefined perioperative time points, intraoperative vasoactive drug consumption, and the incidence of perioperative adverse events.

Results: The incidence of intraoperative hypertension was significantly lower in the SGB group than in the control group (14.3% vs. 37.1%, p = 0.029). Compared with the control group, patients in the SGB group exhibited significantly lower MAP and HR at eight time points ranging from immediately after tracheal intubation until the end of surgery ( p < 0.05). The intraoperative consumption of phentolamine was significantly lower in the SGB group than in the control group [0 (0–4) mg vs. 0 (0–0) mg; p = 0.008]. In contrast, the consumption of norepinephrine was significantly higher in the SGB group [0 (0–0) mg vs. 0 (0–8) mg; p = 0.004]. No statistically significant differences were observed between the two groups in the consumption of esmolol and atropine, or in the incidence of perioperative adverse events.

Conclusion: Ultrasound-guided SGB lowers intraoperative hypertension incidence and phentolamine demand in laparoscopic partial adrenalectomy. Although the SGB group observed a slight increase in the intraoperative dose of norepinephrine, no perioperative adverse events occurred. There was also no significant difference in the incidence of adverse reactions between the two groups.

Related

  1. Effect of Etomidate Induction on Intraoperative Hemodynamics, Postoperative Inflammation, and Recovery After Laparoscopic Sleeve Gastrectomy: A Retrospective Cohort Study.
    Jiazheng Qi, Zhiying Zheng, Yanrong Gu +3
    Drug design, development and therapyPeer-reviewedCC BY-NCFull textSurgery & anaesthesiaEurope PMC
  2. The Impact of Ultrasound-Guided Rectus Sheath Blocks on Intraoperative Anesthetic Requirements and Early Recovery in Laparoscopic Surgery: A Retrospective Cohort Study
    Sherin Abdelhamid, Khaled Abuamra, Ahmed A Khalaf +2
    CureusPeer-reviewedCC BY 4.0Full textSurgery & anaesthesiaPMCEurope PMC
  3. The Efficacy of Ultrasound-Guided Thoracic Erector Spinae Plane Block for Perioperative Analgesia During Laparoscopic Bariatric Surgery in Super-Obese Patients: A Randomized Controlled Trial
    Amany A Eissa, Mostafa Essam Abdelrahman Abdelmohsen, Marwa Zayed +5
    Anesthesiology and pain medicinePeer-reviewedCC BYFull textSurgery & anaesthesiaEurope PMCPMC
  4. Development and validation of a machine learning model for preoperative prediction of intraoperative hypothermia in gynecological laparoscopic surgery: a two-center cohort study
    Chunping Li, Bo Liu, Jianping Zhang +2
    Frontiers in medicinePeer-reviewedCC BYFull textGeneral medicineEurope PMC
  5. Ultrasound Evaluation of Lower-Limb Arterial Morphology and Hemodynamics in Type 2 Diabetes Mellitus Versus Non-Diabetic Controls: A Systematic Review and Meta-Analysis
    Salahaden R. Sultan, Faisal Albin Hajji, Muyaser Fatani
    Journal of clinical medicinePeer-reviewedCC BYFull textGeneral medicineEurope PMC

Cite

BibTeXRIS
BibTeX
@article{nie2026effect,
  title = {{Effect of ultrasound-guided stellate ganglion block on intraoperative hemodynamics in laparoscopic partial adrenalectomy: a randomized clinical trial}},
  author = {Jingyi Nie and Huang Wang and Wenjing Zhang and Hui Wang and Pengqian Hao and Junchai Liu and Jiwen Shang and Weiwei Zhang},
  journal = {Frontiers in Neuroscience},
  year = {2026},
  month = oct,
  doi = {10.3389/fnins.2026.1966414},
  url = {https://www.frontiersin.org/articles/10.3389/fnins.2026.1966414/full},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Effect of ultrasound-guided stellate ganglion block on intraoperative hemodynamics in laparoscopic partial adrenalectomy: a randomized clinical trial
AU  - Jingyi Nie
AU  - Huang Wang
AU  - Wenjing Zhang
AU  - Hui Wang
AU  - Pengqian Hao
AU  - Junchai Liu
AU  - Jiwen Shang
AU  - Weiwei Zhang
PY  - 2026
DA  - 2026/10/26
JO  - Frontiers in Neuroscience
DO  - 10.3389/fnins.2026.1966414
UR  - https://www.frontiersin.org/articles/10.3389/fnins.2026.1966414/full
AB  - Purpose: This study aimed to evaluate the effect of ultrasound-guided stellate ganglion block (SGB) on intraoperative hemodynamic parameters in patients undergoing laparoscopic partial adrenalectomy.  Patients and methods: A total of 72 patients with adrenal tumors scheduled for laparoscopic partial adrenalectomy were enrolled and randomly assigned in a 1:1 ratio to either the stellate ganglion block (SGB) group or the control group. The primary outcome was the incidence of intraoperative hypertension, defined as a systolic blood pressure (SBP) ≥180 mmHg or an increase of ≥30% in mean arterial pressure (MAP) from baseline. Secondary outcomes included MAP and heart rate (HR) measured at nine predefined perioperative time points, intraoperative vasoactive drug consumption, and the incidence of perioperative adverse events.  Results: The incidence of intraoperative hypertension was significantly lower in the SGB group than in the control group (14.3% vs. 37.1%, p = 0.029). Compared with the control group, patients in the SGB group exhibited significantly lower MAP and HR at eight time points ranging from immediately after tracheal intubation until the end of surgery ( p < 0.05). The intraoperative consumption of phentolamine was significantly lower in the SGB group than in the control group [0 (0–4) mg vs. 0 (0–0) mg; p = 0.008]. In contrast, the consumption of norepinephrine was significantly higher in the SGB group [0 (0–0) mg vs. 0 (0–8) mg; p = 0.004]. No statistically significant differences were observed between the two groups in the consumption of esmolol and atropine, or in the incidence of perioperative adverse events.  Conclusion: Ultrasound-guided SGB lowers intraoperative hypertension incidence and phentolamine demand in laparoscopic partial adrenalectomy. Although the SGB group observed a slight increase in the intraoperative dose of norepinephrine, no perioperative adverse events occurred. There was also no significant difference in the incidence of adverse reactions between the two groups.
SN  - 1662-453X
SN  - 1662-4548
ER  -