Skip to content
DraconiticResearch
Search Sources API
203,234 studies31 sourcesUpdated 56 min ago
Peer-reviewedCC BY 4.0Frontiers in Psychiatry

Context presentation and native conversation structure in large language model responses to escalating suicide risk: a controlled multimodel evaluation

4 affiliations
  1. 1Department of Plastic and Aesthetic Surgery, The Second Affiliated Hospital of Guilin Medical University
  2. 2School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine
  3. 3School of Clinical Medicine, Xiangnan University
  4. 4School of Economics, Zhejiang University of Science & Technology

Abstract

Background: Large language models are increasingly used for informal mental health support, yet their safety during escalating suicide-risk conversations may depend on how prior information is presented. Native multi-turn conversations and reconstructed cumulative prompts differ not only in the presence of prior model responses but also in prompt reconstruction, information concentration, message positioning, explicit integration cues, and conversation-state processing.

Objective: This study compared suicide-risk recognition, direct safety inquiry, response urgency, and timely real-world intervention across isolated current-turn prompts, reconstructed cumulative user-only prompts, and native continuous multi-turn conversations.

Methods: We conducted a controlled repeated-measures evaluation of ChatGPT, Gemini, and Doubao using 12 standardized five-turn trajectories: 4 direct suicide-risk trajectories, 4 implicit or internally inconsistent risk trajectories, and 4 non-suicidal high-distress controls. Each trajectory was evaluated under three context-presentation formats. The 24 model-trajectory combinations were treated as matched repeated-measures units nested within 8 independent risk-trajectory blocks. Primary contrasts were estimated using exact trajectory-level sign-flip tests and trajectory-block bootstrap confidence intervals. Turn-level outcomes were analyzed using multilevel mixed-effects models. Exploratory condition-by-model heterogeneity was assessed using a trajectory-blocked exact permutation sensitivity analysis, with a trajectory-clustered interaction model used only as a secondary asymptotic check.

Results: Timely appropriate intervention occurred in 10/24 isolated current-turn observations (41.7%), 21/24 reconstructed cumulative observations (87.5%), and 12/24 native continuous observations (50.0%). On average across the three systems, reconstructed cumulative presentation exceeded isolated input by 45.8 percentage points (95% trajectory-block bootstrap CI, 25.0 to 66.7; Holm-adjusted exact P = .031), whereas native continuous performance was 37.5 percentage points lower than reconstructed cumulative performance (95% trajectory-block bootstrap CI, −50.0 to −25.0; Holm-adjusted exact P = .031). Exploratory model-specific analyses indicated substantial heterogeneity: the native-versus-reconstructed contrast was largest for Doubao, smaller and statistically imprecise for Gemini, and absent for ChatGPT.

Conclusions: On average across the three evaluated systems, reconstructed cumulative user-only prompts outperformed native continuous conversations, although exploratory model-specific patterns were heterogeneous. Because the formats also differed in prompt reconstruction, information salience, message positioning, explicit integration instructions, and native conversation-state processing, the contrast cannot isolate the causal effect of prior model responses.

Related

  1. German Adaptation and Psychometric Evaluation of the Conversation Questionnaire
    Peter Bang, Lilly Fimpel, Joel Baisch +3
    PsyArXivPreprintAll rights reservedFull textPsychiatry & mental healthOSF
  2. Navigating Dynamic Risks: Outcome Monitoring and Evaluation under Escalating Risk
    Corinna Lorenz, Nicola Ferdinand
    PsyArXivPreprintCC BY 4.0Full textNeurosciencePhysiologyOSF
  3. Large Language Models' Simulation of Patient Comprehension of Discharge Summaries: Multimodel Evaluation Study.
    Xinyao Ma, Rui Zhu, Zihao Wang +4
    Journal of medical Internet researchPeer-reviewedCC BYFull textEpidemiology & public healthEurope PMC
  4. Double-blind, placebo-controlled randomised clinical trial on flexible doses of escitalopram and naltrexone in the treatment of men with compulsive sexual behaviour disorder: study protocol presentation
    Michał Lew-Starowicz, Małgorzata Draps, Kacper Wilk +2
    BMJ OpenPeer-reviewedCC BY-NC 4.0Full textPsychiatry & mental healthDOAJCrossrefPMC
  5. De-escalating Therapy in Obstructive Sleep Apnoea After Glucagon-Like Peptide-1 Receptor Agonist-Induced Weight Loss: A Narrative Review
    Wares Jalil
    CureusPeer-reviewedCC BYFull textGeneral medicineEurope PMC
BibTeX
@article{liu2026context,
  title = {{Context presentation and native conversation structure in large language model responses to escalating suicide risk: a controlled multimodel evaluation}},
  author = {Jueqiao Liu and Xiaoyi Chen and Jun Cai and Xuchen Luo and Wei Xiao and Jiehua Deng},
  journal = {Frontiers in Psychiatry},
  year = {2026},
  month = oct,
  doi = {10.3389/fpsyt.2026.1962098},
  url = {https://www.frontiersin.org/articles/10.3389/fpsyt.2026.1962098/full},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Context presentation and native conversation structure in large language model responses to escalating suicide risk: a controlled multimodel evaluation
AU  - Jueqiao Liu
AU  - Xiaoyi Chen
AU  - Jun Cai
AU  - Xuchen Luo
AU  - Wei Xiao
AU  - Jiehua Deng
PY  - 2026
DA  - 2026/10/16
JO  - Frontiers in Psychiatry
DO  - 10.3389/fpsyt.2026.1962098
UR  - https://www.frontiersin.org/articles/10.3389/fpsyt.2026.1962098/full
AB  - Background: Large language models are increasingly used for informal mental health support, yet their safety during escalating suicide-risk conversations may depend on how prior information is presented. Native multi-turn conversations and reconstructed cumulative prompts differ not only in the presence of prior model responses but also in prompt reconstruction, information concentration, message positioning, explicit integration cues, and conversation-state processing.  Objective: This study compared suicide-risk recognition, direct safety inquiry, response urgency, and timely real-world intervention across isolated current-turn prompts, reconstructed cumulative user-only prompts, and native continuous multi-turn conversations.  Methods: We conducted a controlled repeated-measures evaluation of ChatGPT, Gemini, and Doubao using 12 standardized five-turn trajectories: 4 direct suicide-risk trajectories, 4 implicit or internally inconsistent risk trajectories, and 4 non-suicidal high-distress controls. Each trajectory was evaluated under three context-presentation formats. The 24 model-trajectory combinations were treated as matched repeated-measures units nested within 8 independent risk-trajectory blocks. Primary contrasts were estimated using exact trajectory-level sign-flip tests and trajectory-block bootstrap confidence intervals. Turn-level outcomes were analyzed using multilevel mixed-effects models. Exploratory condition-by-model heterogeneity was assessed using a trajectory-blocked exact permutation sensitivity analysis, with a trajectory-clustered interaction model used only as a secondary asymptotic check.  Results: Timely appropriate intervention occurred in 10/24 isolated current-turn observations (41.7%), 21/24 reconstructed cumulative observations (87.5%), and 12/24 native continuous observations (50.0%). On average across the three systems, reconstructed cumulative presentation exceeded isolated input by 45.8 percentage points (95% trajectory-block bootstrap CI, 25.0 to 66.7; Holm-adjusted exact P = .031), whereas native continuous performance was 37.5 percentage points lower than reconstructed cumulative performance (95% trajectory-block bootstrap CI, −50.0 to −25.0; Holm-adjusted exact P = .031). Exploratory model-specific analyses indicated substantial heterogeneity: the native-versus-reconstructed contrast was largest for Doubao, smaller and statistically imprecise for Gemini, and absent for ChatGPT.  Conclusions: On average across the three evaluated systems, reconstructed cumulative user-only prompts outperformed native continuous conversations, although exploratory model-specific patterns were heterogeneous. Because the formats also differed in prompt reconstruction, information salience, message positioning, explicit integration instructions, and native conversation-state processing, the contrast cannot isolate the causal effect of prior model responses.
SN  - 1664-0640
ER  -