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Peer-reviewedCC BYPediatric transplantation

Guidance on the Ethical Use of Mandates for Vaccination Prior to Organ Transplantation in Children: An Analysis From the IPTA Ethics Committee

  • M. Damian1
  • M. A. Freeman2,3
  • S. Rao4
  • A. Wightman5
  • T. Blydt‐Hansen6
  • the IPTA Ethics Committee
6 affiliations
  1. 1Department of Pediatrics Children's Healthcare of Atlanta, Emory University School of Medicine Atlanta Georgia USA
  2. 2Department of Pediatrics Penn State Health Golisano Children's Hospital, Penn State College of Medicine Hershey Pennsylvania USA
  3. 3Department of Humanities Penn State Health Golisano Children's Hospital, Penn State College of Medicine Hershey Pennsylvania USA
  4. 4Department of Pediatric Surgery Narayana Health Hospitals Bengaluru India
  5. 5Department of Pediatrics, Seattle Children's Research Institute, Treuman Katz Center for Pediatric Bioethics and Palliative Care University of Washington School of Medicine Seattle Washington USA
  6. 6Department of Pediatrics University of British Columbia Vancouver British Columbia Canada
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Abstract

Background: IPTA is a multidisciplinary international professional organization composed of pediatric transplant experts who aim to improve the health of all children with end‐stage organ failure by advancing the science and practice of pediatric transplantation worldwide. The IPTA Ethics committee seeks to provide guidance on ethical issues pertaining to pediatric transplantation in a global context. There is broad consensus that pre‐transplant vaccination decreases the risk of many preventable diseases and the IPTA leadership, committees, and membership unequivocally support immunizations for all children. However, the use of mandated vaccination as criteria for transplant eligibility in the under‐vaccinated pediatric population remains ethically complex.

Methods: In this guidance document, we explore ethical arguments for and against the use of mandated vaccination as a requirement for transplant eligibility.

Results: Considerations in this ethical analysis included assessments of the potential benefits and/or harms experienced by potential recipients for whom vaccination may be required, concerns for appropriate respect for and the limits of parental authority, and societal considerations including organ stewardship, the social contract implicit in organ allocation practices, broader considerations of population safety, and disparities in opportunities for transplant.

Conclusion: This analysis is designed to support clinicians, transplant programs, and, where applicable, regional and national policy makers in evaluating the ethical justifiability of pre‐transplant vaccination requirements for pediatric solid organ transplant candidates. It does not prescribe a single policy approach for all settings but rather offers a structured ethical framework and consensus statements to inform local, regional, and national deliberation.

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Cite

BibTeXRIS
BibTeX
@article{damian2026guidance,
  title = {{Guidance on the Ethical Use of Mandates for Vaccination Prior to Organ Transplantation in Children: An Analysis From the IPTA Ethics Committee}},
  author = {M. Damian and M. A. Freeman and S. Rao and A. Wightman and T. Blydt‐Hansen and the IPTA Ethics Committee},
  journal = {Pediatric transplantation},
  year = {2026},
  month = oct,
  doi = {10.1111/petr.70488},
  url = {https://europepmc.org/article/PMC/PMC13722998},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Guidance on the Ethical Use of Mandates for Vaccination Prior to Organ Transplantation in Children: An Analysis From the IPTA Ethics Committee
AU  - M. Damian
AU  - M. A. Freeman
AU  - S. Rao
AU  - A. Wightman
AU  - T. Blydt‐Hansen
AU  - the IPTA Ethics Committee
PY  - 2026
DA  - 2026/10/31
JO  - Pediatric transplantation
DO  - 10.1111/petr.70488
UR  - https://europepmc.org/article/PMC/PMC13722998
AB  - Background: IPTA is a multidisciplinary international professional organization composed of pediatric transplant experts who aim to improve the health of all children with end‐stage organ failure by advancing the science and practice of pediatric transplantation worldwide. The IPTA Ethics committee seeks to provide guidance on ethical issues pertaining to pediatric transplantation in a global context. There is broad consensus that pre‐transplant vaccination decreases the risk of many preventable diseases and the IPTA leadership, committees, and membership unequivocally support immunizations for all children. However, the use of mandated vaccination as criteria for transplant eligibility in the under‐vaccinated pediatric population remains ethically complex.  Methods: In this guidance document, we explore ethical arguments for and against the use of mandated vaccination as a requirement for transplant eligibility.  Results: Considerations in this ethical analysis included assessments of the potential benefits and/or harms experienced by potential recipients for whom vaccination may be required, concerns for appropriate respect for and the limits of parental authority, and societal considerations including organ stewardship, the social contract implicit in organ allocation practices, broader considerations of population safety, and disparities in opportunities for transplant.  Conclusion: This analysis is designed to support clinicians, transplant programs, and, where applicable, regional and national policy makers in evaluating the ethical justifiability of pre‐transplant vaccination requirements for pediatric solid organ transplant candidates. It does not prescribe a single policy approach for all settings but rather offers a structured ethical framework and consensus statements to inform local, regional, and national deliberation.
SN  - 1397-3142
SN  - 1399-3046
ER  -