Preprocedural CT-guided anatomical assessment shortens intubation time and improves patient and operator experience during unsedated colonoscopy: a randomised controlled trial
- 1Peking Union Medical College Hospital
Abstract
MESSAGELooping is a major cause of difficult and painful insertion during unsedated colonoscopy, yet strategies are largely guided by trial and error; prolonged insertion may jeopardise completion, discourage future surveillance and is associated with lower adenoma detection. In this randomised trial of 141 patients, protocolised review of pre-existing abdominal-pelvic computed tomography (CT) anticipated colonic anatomy and shortened caecal intubation time by 136 s, while reducing pain, discomfort and operator workload and increasing willingness to repeat colonoscopy. Effects were largest in N-loop and alpha-loop configurations, which accounted for 83% of patients. Routinely acquired CT could support anatomy-informed colonoscope insertion especially when anesthesia services are limited or sedation poses an elevated risk.
Related
- Learning and deskilling effects of artificial intelligence in colonoscopy among endoscopists with different levels of experience: a pragmatic, prospective trial
- A real-world single-center study on the effects of low-volume polyethylene glycol electrolyte solution and rhubarb for colonoscopy preparation: quality, tolerance, and experience
- Incremental Anatomical Value of CT Angiography Beyond Echocardiography in the Preoperative Assessment of Pediatric Conotruncal Anomalies: A Surgical Correlation Study
- Comprehensive Cardiac Computed Tomography for Anatomical Assessment, Functional Analysis, and Myocardial Tissue Characterization in a Patient With Coronary Anomaly and Cardiac Amyloidosis
- Retrospective CBCT-based anatomical assessment of mandibular first and second molars: a cross-sectional study with potential implications for immediate implant planning.
BibTeX
@misc{he2026preprocedural,
title = {{Preprocedural CT-guided anatomical assessment shortens intubation time and improves patient and operator experience during unsedated colonoscopy: a randomised controlled trial}},
author = {K. He and K. Pang and J. Liu and Q. Wang and Y. Min and Y. Wang and Y. Liu and Y. Hu and H. Wang and R. Li and Q. Jiang and Q. Wang and T. Xu and S. Zhang and W. Liu and D. Wu},
howpublished = {medRxiv},
year = {2026},
month = sep,
doi = {10.64898/2026.09.22.26363660},
url = {https://www.medrxiv.org/content/10.64898/2026.09.22.26363660v1},
note = {CC BY-NC-ND},
}
RIS
TY - UNPB
TI - Preprocedural CT-guided anatomical assessment shortens intubation time and improves patient and operator experience during unsedated colonoscopy: a randomised controlled trial
AU - K. He
AU - K. Pang
AU - J. Liu
AU - Q. Wang
AU - Y. Min
AU - Y. Wang
AU - Y. Liu
AU - Y. Hu
AU - H. Wang
AU - R. Li
AU - Q. Jiang
AU - Q. Wang
AU - T. Xu
AU - S. Zhang
AU - W. Liu
AU - D. Wu
PY - 2026
DA - 2026/09/22
PB - medRxiv
DO - 10.64898/2026.09.22.26363660
UR - https://www.medrxiv.org/content/10.64898/2026.09.22.26363660v1
AB - MESSAGELooping is a major cause of difficult and painful insertion during unsedated colonoscopy, yet strategies are largely guided by trial and error; prolonged insertion may jeopardise completion, discourage future surveillance and is associated with lower adenoma detection. In this randomised trial of 141 patients, protocolised review of pre-existing abdominal-pelvic computed tomography (CT) anticipated colonic anatomy and shortened caecal intubation time by 136 s, while reducing pain, discomfort and operator workload and increasing willingness to repeat colonoscopy. Effects were largest in N-loop and alpha-loop configurations, which accounted for 83% of patients. Routinely acquired CT could support anatomy-informed colonoscope insertion especially when anesthesia services are limited or sedation poses an elevated risk.
ER -