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Peer-reviewedCC BY-NC-ND结直肠肛门外科

Perianal granular cell tumor misdiagnosed as anal fistula: a case report and literature re-view

  1. 1Department of Anorectal Surgery, Guang'an District People's Hospital, Guang'an 638000, Sichuan, China

Abstract

Perianal granular cell tumor is a rare neurogenic soft tissue tumor with a predominantly benign course, insidious growth, and atypical symptoms, making it highly susceptible to misdiagnosis as a common perianal infectious disease. This article reports diagnosis and treatment process of a patient with perianal granular cell tumor misdiagnosed as anal fistula. The patient presented with recurrent perianal dull pain, local induration, and intermittent slight exudation, without obvious redness, swelling, heat, pain, or signs of acute infection. Based on perianal examination and clinical experience, a preliminary diagnosis of simple anal fistula was made. Intraoperative exploration revealed no typical cord-like sinus tract structure of anal fistula, and the local lesion tissue was completely removed and sent for pathological examination. The final diagnosis was perianal granular cell tumor. This article details the clinical data, diagnostic process, treatment strategy, and prognosis of this case, and reviews the relevant literature to discuss the morphological characteristics, differential diagnostic points, and treatment strategies for perianal granular cell tumors, with the aim of reducing the clinical misdiagnosis rate and improving patient outcomes.

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BibTeX
@article{jinwei2026perianal,
  title = {{Perianal granular cell tumor misdiagnosed as anal fistula: a case report and literature re-view}},
  author = {Ruan Jinwei and Liu Zhengkang and Yang Tingting},
  journal = {结直肠肛门外科},
  year = {2026},
  month = aug,
  doi = {10.19668/j.cnki.issn1674-0491.2026.04.016},
  url = {https://doi.org/10.19668/j.cnki.issn1674-0491.2026.04.016},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Perianal granular cell tumor misdiagnosed as anal fistula: a case report and literature re-view
AU  - Ruan Jinwei
AU  - Liu Zhengkang
AU  - Yang Tingting
PY  - 2026
DA  - 2026/08/01
JO  - 结直肠肛门外科
DO  - 10.19668/j.cnki.issn1674-0491.2026.04.016
UR  - https://doi.org/10.19668/j.cnki.issn1674-0491.2026.04.016
AB  - Perianal granular cell tumor is a rare neurogenic soft tissue tumor with a predominantly benign course, insidious growth, and atypical symptoms, making it highly susceptible to misdiagnosis as a common perianal infectious disease. This article reports diagnosis and treatment process of a patient with perianal granular cell tumor misdiagnosed as anal fistula. The patient presented with recurrent perianal dull pain, local induration, and intermittent slight exudation, without obvious redness, swelling, heat, pain, or signs of acute infection. Based on perianal examination and clinical experience, a preliminary diagnosis of simple anal fistula was made. Intraoperative exploration revealed no typical cord-like sinus tract structure of anal fistula, and the local lesion tissue was completely removed and sent for pathological examination. The final diagnosis was perianal granular cell tumor. This article details the clinical data, diagnostic process, treatment strategy, and prognosis of this case, and reviews the relevant literature to discuss the morphological characteristics, differential diagnostic points, and treatment strategies for perianal granular cell tumors, with the aim of reducing the clinical misdiagnosis rate and improving patient outcomes.
SN  - 1674-0491
ER  -