Medication adherence among patients with psychiatric illness: Role of internalized stigma
Abstract
Background: Adherence to prescribed psychotropic medications is vital for effective management of psychiatric illnesses. Despite this, medication non-adherence (MNA) remains a significant barrier to achieving optimal outcomes, often resulting in relapse, poor prognosis, and increased health care costs. Among various influencing factors, internalized stigma is increasingly recognized as a critical component that affects medication adherence. Aims: To assess medication adherence among patients with psychiatric illnesses, study their attitudes toward psychotropic medication, examine the extent of internalized stigma, and identify key factors influencing adherence. Methods: A cross-sectional observational study was conducted in the psychiatry outpatient department of a tertiary care hospital. A total of 100 adult psychiatric outpatients, diagnosed as per DSM-5 criteria and currently receiving psychotropic medication, were included. Sociodemographic profile and illness-related variables were collected. Morisky Medication Adherence Scale (MMAS-8), Drug Attitude Inventory (DAI-10), and Internalized Stigma of Mental Illness (ISMI) Scales were applied to assess medication adherence, drug attitude, and stigma, respectively. Chi-square and Fisher’s exact tests were used for statistical analysis. Results: Most participants showed medium adherence (74%), positive drug attitude (91%), and low internalized stigma (82%). Common barriers to adherence were insufficient illness-related knowledge (46.43%) and forgetfulness (33.39%). A significant association was found between higher internalized stigma and lower medication adherence (P < 0.001). Conclusion: Internalized stigma significantly affects medication adherence. Enhancing awareness and reducing stigma may improve medication adherence and treatment outcomes.
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BibTeX
@article{yaragandla2026medication,
title = {{Medication adherence among patients with psychiatric illness: Role of internalized stigma}},
author = {Yasaswi Yaragandla and Madhavi Kodali and Therissa Benerji Ganta},
journal = {Journal of Dr. NTR University of Health Sciences},
year = {2026},
month = jul,
doi = {10.4103/jdrntruhs.jdrntruhs_78_25},
url = {https://doi.org/10.4103/jdrntruhs.jdrntruhs_78_25},
note = {CC BY-NC-SA},
}
RIS
TY - JOUR
TI - Medication adherence among patients with psychiatric illness: Role of internalized stigma
AU - Yasaswi Yaragandla
AU - Madhavi Kodali
AU - Therissa Benerji Ganta
PY - 2026
DA - 2026/07/01
JO - Journal of Dr. NTR University of Health Sciences
DO - 10.4103/jdrntruhs.jdrntruhs_78_25
UR - https://doi.org/10.4103/jdrntruhs.jdrntruhs_78_25
AB - Background: Adherence to prescribed psychotropic medications is vital for effective management of psychiatric illnesses. Despite this, medication non-adherence (MNA) remains a significant barrier to achieving optimal outcomes, often resulting in relapse, poor prognosis, and increased health care costs. Among various influencing factors, internalized stigma is increasingly recognized as a critical component that affects medication adherence. Aims: To assess medication adherence among patients with psychiatric illnesses, study their attitudes toward psychotropic medication, examine the extent of internalized stigma, and identify key factors influencing adherence. Methods: A cross-sectional observational study was conducted in the psychiatry outpatient department of a tertiary care hospital. A total of 100 adult psychiatric outpatients, diagnosed as per DSM-5 criteria and currently receiving psychotropic medication, were included. Sociodemographic profile and illness-related variables were collected. Morisky Medication Adherence Scale (MMAS-8), Drug Attitude Inventory (DAI-10), and Internalized Stigma of Mental Illness (ISMI) Scales were applied to assess medication adherence, drug attitude, and stigma, respectively. Chi-square and Fisher’s exact tests were used for statistical analysis. Results: Most participants showed medium adherence (74%), positive drug attitude (91%), and low internalized stigma (82%). Common barriers to adherence were insufficient illness-related knowledge (46.43%) and forgetfulness (33.39%). A significant association was found between higher internalized stigma and lower medication adherence (P < 0.001). Conclusion: Internalized stigma significantly affects medication adherence. Enhancing awareness and reducing stigma may improve medication adherence and treatment outcomes.
SN - 2278-1889
SN - 2277-8632
ER -