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Peer-reviewedCC BY 4.0Frontiers in Endocrinology

Obesity in adults: overview of a clinical practice guideline for South Africa

  • Marli Conradie-Smit1
  • Wayne May2
  • Clayton Arendse3
  • Jason Bantjes4
  • Zaheer Bayat5
  • Elna Barnard6
  • Sindeep Bhana7
  • Nomathemba Chandiwana8
  • Annibale Cois9
  • Paula N. Diab10
  • Zodwa Dire11
  • Virginia R. Fourie2
14 more authors
  • Julia H. Goedecke12
  • Jocelyn Hellig13
  • Zachary Koto14
  • Kathleen Mawson15
  • Makama Andries Monyeki16
  • Angela Murphy17
  • Christina Nieuwoudt18
  • Marisa Noeth19
  • Nicole Pearce20
  • Joanna Skelton21
  • Thinus (JGM) Smit22
  • Sanjeev Sockalingam20,23,24
  • Francois H. van Zyl25
  • Jeanne Lubbe26
26 affiliations
  1. 1Division of Endocrinology, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Academic Hospital, Cape Town, South Africa
  2. 2Cape Town Bariatric Clinic, Kingsbury Hospital, Cape Town, South Africa
  3. 3Department of Psychiatry, Stellenbosch University and Department of Psychology Tygerberg Academic Hospital, Cape Town, South Africa
  4. 4Mental health, Alcohol, Substance use and Tobacco Research Unit, South African Medical Research Council; Department of Psychiatry and Mental Health, University of Cape Town; Institute for Life Course Health Research, Department of Global Health, Stellenbosch University, Cape Town, South Africa
  5. 5Division of Endocrinology, Department of Internal Medicine, Helen Joseph Tertiary Hospital and University of the Witwatersrand, Johannesburg, South Africa
  6. 6M-Care Optima Bloemcare Psychiatric Hospital, Bloemfontein, South Africa
  7. 7Center for Advance Medicine, Johannesburg; Chris Hani Baragwanath Academic Hospital, University of Witwatersrand, Johannesburg, South Africa
  8. 8Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa
  9. 9Burden of Disease Research Unit, South African Medical Research Council; Division of Epidemiology and Biostatistics, School of Public Health, University of Cape Town, Cape Town, South Africa
  10. 10Atrium Diabetes Center, Gillits, Kwazulu-Natal; Dept of Family Medicine University of Pretoria, Pretoria, South Africa
  11. 11Division of Endocrinology, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital and University of the Witwatersrand, Johannesburg, South Africa
  12. 12Biomedical Research and Innovation Platform, South African Medical Research Council, Cape Town, South Africa
  13. 13Life Kingsbury Hospital, Cape Town, South Africa
  14. 14Department of Surgery, Sefako Makgatho Health Science University and Dr George Mukhari Academic Hospital, Ga-Rankuwa, Pretoria, South Africa
  15. 15Department of Psychiatry, Stellenbosch University and Tygerberg Academic Hospital, Cape Town, South Africa
  16. 16Physical Activity, Sport and Recreation (PhASRec), Faculty of Health Sciences, North-West University, Potchefstroom, South Africa
  17. 17Sunward Park Medical Center, Boksburg, South Africa
  18. 18Zuid Afrikaans Hospital, Pretoria, South Africa
  19. 19Zuid-Afrikaans Hospital; Dept Internal Medicine University of Pretoria, Pretoria, South Africa
  20. 20Obesity Canada, Edmonton, AB, Canada
  21. 21Busamed Gateway Private Hospital, Umhlanga, Durban, South Africa
  22. 22Zuid Afrikaans Hospital, Obesity Health Centre; Department of Surgery, Sefako Makgatho Health Sciences University, Pretoria, South Africa
  23. 23Department of Psychiatry, University of Toronto, Centre for Addiction and Mental Health, Toronto, ON, Canada
  24. 24Bariatric Surgery Program, University Health Network, Toronto, ON, Canada
  25. 25Private Practice and CPR Trial Centre; Mediclinic Private Hospital, Worcester, South Africa
  26. 26Division Surgery, Department of Surgical Sciences, Stellenbosch University and Tygerberg Academic Hospital, Cape Town, South Africa
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Abstract

Obesity is a multifactorial condition posing an escalating public health burden in South Africa, where access to effective, evidence-based interventions remains constrained. This overview describes the South African adaptation of the Canadian Adult Obesity Clinical Practice Guideline, contextualized through locoregional evidence to provide pragmatic, setting-appropriate recommendations and culminating in a comprehensive 18-chapter guideline. Key areas of uncertainty — including HIV-associated weight trajectories and culturally specific perspectives on obesity — are acknowledged, with guidance offered where evidence permits. This guideline addresses a critical gap in culturally responsive, resource-sensitive obesity management within the African healthcare context.

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Cite

BibTeXRIS
BibTeX
@article{conradiesmit2026obesity,
  title = {{Obesity in adults: overview of a clinical practice guideline for South Africa}},
  author = {Marli Conradie-Smit and Wayne May and Clayton Arendse and Jason Bantjes and Zaheer Bayat and Elna Barnard and Sindeep Bhana and Nomathemba Chandiwana and Annibale Cois and Paula N. Diab and Zodwa Dire and Virginia R. Fourie and Julia H. Goedecke and Jocelyn Hellig and Zachary Koto and Kathleen Mawson and Makama Andries Monyeki and Angela Murphy and Christina Nieuwoudt and Marisa Noeth and Nicole Pearce and Joanna Skelton and Thinus (JGM) Smit and Sanjeev Sockalingam and Francois H. van Zyl and Jeanne Lubbe},
  journal = {Frontiers in Endocrinology},
  year = {2026},
  month = oct,
  doi = {10.3389/fendo.2026.1875018},
  url = {https://doi.org/10.3389/fendo.2026.1875018},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Obesity in adults: overview of a clinical practice guideline for South Africa
AU  - Marli Conradie-Smit
AU  - Wayne May
AU  - Clayton Arendse
AU  - Jason Bantjes
AU  - Zaheer Bayat
AU  - Elna Barnard
AU  - Sindeep Bhana
AU  - Nomathemba Chandiwana
AU  - Annibale Cois
AU  - Paula N. Diab
AU  - Zodwa Dire
AU  - Virginia R. Fourie
AU  - Julia H. Goedecke
AU  - Jocelyn Hellig
AU  - Zachary Koto
AU  - Kathleen Mawson
AU  - Makama Andries Monyeki
AU  - Angela Murphy
AU  - Christina Nieuwoudt
AU  - Marisa Noeth
AU  - Nicole Pearce
AU  - Joanna Skelton
AU  - Thinus (JGM) Smit
AU  - Sanjeev Sockalingam
AU  - Francois H. van Zyl
AU  - Jeanne Lubbe
PY  - 2026
DA  - 2026/10/12
JO  - Frontiers in Endocrinology
DO  - 10.3389/fendo.2026.1875018
UR  - https://doi.org/10.3389/fendo.2026.1875018
AB  - Obesity is a multifactorial condition posing an escalating public health burden in South Africa, where access to effective, evidence-based interventions remains constrained. This overview describes the South African adaptation of the Canadian Adult Obesity Clinical Practice Guideline, contextualized through locoregional evidence to provide pragmatic, setting-appropriate recommendations and culminating in a comprehensive 18-chapter guideline. Key areas of uncertainty — including HIV-associated weight trajectories and culturally specific perspectives on obesity — are acknowledged, with guidance offered where evidence permits. This guideline addresses a critical gap in culturally responsive, resource-sensitive obesity management within the African healthcare context.
SN  - 1664-2392
ER  -