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Peer-reviewedCC BY-NCEuropean journal of public health

Social inequality in COVID-19-related morbidity and mortality during the first three waves of the pandemic in Denmark: a nationwide register-based cohort study, 2020–22

  1. 1National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.

Abstract

This nationwide cohort study aimed to examine social inequality in coronavirus disease 2019 (COVID-19)-related morbidity and mortality in Denmark during the first three pandemic waves using different individual-level measures of socioeconomic position. Additionally, the study aimed to investigate potential changes in social inequality in COVID-19-related morbidity and mortality throughout the pandemic. The cohort comprised the total Danish population. Individual-level, linkable register data were extracted and analysed for all residents of Denmark across the first three pandemic waves (26 February 2020-15 April 2022). Poisson regression of incidence rates (IR) was performed to compare COVID-19-related morbidity and mortality rates between individuals grouped according to length of educational, household income, and employment status. Social inequality in COVID-19-related hospitalization, ICU admission, and mortality was observed across the three measures of socioeconomic position. The social inequality in COVID-19-related hospitalization and ICU admission increased throughout the pandemic. The incidence rate ratio (IRR) for COVID-19-related hospitalization for individuals with elementary vs. long education increased from 0.93 [95% confidence interval (CI): 0.83-1.05] in wave 1 to 1.75 (1.67-1.84) in wave 3. The corresponding changes in IRRs for low vs. high household income and unemployed vs. employed individuals were 0.87 (0.75-1.01) to 1.83 (1.71-1.95) and 1.04 (0.86-1.25) to 3.23 (3.02-3.45), respectively. Social inequality in COVID-19-related morbidity changed during the pandemic. Interventions that reduce differential vulnerability to and consequences of COVID-19 between groups defined by socioeconomic position seem to be increasingly important as pandemics evolve.

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BibTeX
@article{kjærulff2026social,
  title = {{Social inequality in COVID-19-related morbidity and mortality during the first three waves of the pandemic in Denmark: a nationwide register-based cohort study, 2020–22}},
  author = {Thora M Kjærulff and Mikkel B Nielsen and Michelle T Pedersen and Kristine Bihrmann and Janne S Tolstrup and Annette K Ersbøll},
  journal = {European journal of public health},
  year = {2026},
  month = oct,
  doi = {10.1093/eurpub/ckag196},
  url = {https://europepmc.org/article/PMC/PMC13722283},
  note = {CC BY-NC},
}
RIS
TY  - JOUR
TI  - Social inequality in COVID-19-related morbidity and mortality during the first three waves of the pandemic in Denmark: a nationwide register-based cohort study, 2020–22
AU  - Thora M Kjærulff
AU  - Mikkel B Nielsen
AU  - Michelle T Pedersen
AU  - Kristine Bihrmann
AU  - Janne S Tolstrup
AU  - Annette K Ersbøll
PY  - 2026
DA  - 2026/10/01
JO  - European journal of public health
DO  - 10.1093/eurpub/ckag196
UR  - https://europepmc.org/article/PMC/PMC13722283
AB  - This nationwide cohort study aimed to examine social inequality in coronavirus disease 2019 (COVID-19)-related morbidity and mortality in Denmark during the first three pandemic waves using different individual-level measures of socioeconomic position. Additionally, the study aimed to investigate potential changes in social inequality in COVID-19-related morbidity and mortality throughout the pandemic. The cohort comprised the total Danish population. Individual-level, linkable register data were extracted and analysed for all residents of Denmark across the first three pandemic waves (26 February 2020-15 April 2022). Poisson regression of incidence rates (IR) was performed to compare COVID-19-related morbidity and mortality rates between individuals grouped according to length of educational, household income, and employment status. Social inequality in COVID-19-related hospitalization, ICU admission, and mortality was observed across the three measures of socioeconomic position. The social inequality in COVID-19-related hospitalization and ICU admission increased throughout the pandemic. The incidence rate ratio (IRR) for COVID-19-related hospitalization for individuals with elementary vs. long education increased from 0.93 [95% confidence interval (CI): 0.83-1.05] in wave 1 to 1.75 (1.67-1.84) in wave 3. The corresponding changes in IRRs for low vs. high household income and unemployed vs. employed individuals were 0.87 (0.75-1.01) to 1.83 (1.71-1.95) and 1.04 (0.86-1.25) to 3.23 (3.02-3.45), respectively. Social inequality in COVID-19-related morbidity changed during the pandemic. Interventions that reduce differential vulnerability to and consequences of COVID-19 between groups defined by socioeconomic position seem to be increasingly important as pandemics evolve.
SN  - 1101-1262
SN  - 1464-360X
ER  -