Homochiral Evolution from Self-Assembly of Chiral Block Copolymers.
- 1Department of Chemical Engineering, National Tsing Hua University, No. 101, Section 2, Kuang-Fu Road, Hsinchu30013, Taiwan, R.O.C.
Abstract
A block copolymer containing a chiral block is referred to as a chiral block copolymer, which can form a helical phase (H*) in diblock copolymers and an alternating gyroid phase (GA) in triblock terpolymers with controlled chirality from self-assembly, as evidenced by electron tomography. Polylactide-containing chiral block copolymers can be used as a representative system for the investigation of homochiral evolution from molecular chirality examined by electronic circular dichroism (ECD) to conformational chirality examined by C═O vibrational circular dichroism (VCD), and finally to phase chirality characterized by electron tomography, with C-O-C VCD providing insight into interchain chiral interactions. The intra- and interchain contributions should be evaluated in the context of the specific molecular structure and sample conditions. By taking advantage of noncovalent chirality induction, it is feasible to introduce a chiral bias by associating a chiral dopant with an achiral block, giving H* with controlled chirality from an achiral block copolymer. This Viewpoint highlights the fundamental principles, providing perspectives on the design of chiral soft materials for device applications.
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BibTeX
@article{shao2026homochiral,
title = {{Homochiral Evolution from Self-Assembly of Chiral Block Copolymers.}},
author = {Sheng-Wei Shao and Rong-Ming Ho},
journal = {ACS macro letters},
year = {2026},
month = oct,
doi = {10.1021/acsmacrolett.6c00449},
url = {https://europepmc.org/article/MED/42899744},
note = {CC BY},
}
RIS
TY - JOUR
TI - Homochiral Evolution from Self-Assembly of Chiral Block Copolymers.
AU - Sheng-Wei Shao
AU - Rong-Ming Ho
PY - 2026
DA - 2026/10/01
JO - ACS macro letters
DO - 10.1021/acsmacrolett.6c00449
UR - https://europepmc.org/article/MED/42899744
AB - A block copolymer containing a chiral block is referred to as a chiral block copolymer, which can form a helical phase (H*) in diblock copolymers and an alternating gyroid phase (GA) in triblock terpolymers with controlled chirality from self-assembly, as evidenced by electron tomography. Polylactide-containing chiral block copolymers can be used as a representative system for the investigation of homochiral evolution from molecular chirality examined by electronic circular dichroism (ECD) to conformational chirality examined by C═O vibrational circular dichroism (VCD), and finally to phase chirality characterized by electron tomography, with C-O-C VCD providing insight into interchain chiral interactions. The intra- and interchain contributions should be evaluated in the context of the specific molecular structure and sample conditions. By taking advantage of noncovalent chirality induction, it is feasible to introduce a chiral bias by associating a chiral dopant with an achiral block, giving H* with controlled chirality from an achiral block copolymer. This Viewpoint highlights the fundamental principles, providing perspectives on the design of chiral soft materials for device applications.
SN - 2161-1653
ER -